Characterization of the type IV pilin from Coxicella burnetii

The gram negative bacteria Coxicella burnetii and Francisella tularensis are the causative agents of Q fever and tularaemia, respectively. Infection by either organism can result in high mortality rates, especially in immuno-compromised individuals; in addition, there are very limited options for detection of both C. burnetii and F. tularensis. Recent evidence shows that both bacteria have functional type II secretion system (T2SS) and type IV pilus (T4P), and that functional T4P affect virulence. Sequence analysis indicates that proteins cbu0156 and ftn0389 are the major pilins of C.

Campus Public Health Emergency Simulations

School closure during an infectious disease outbreak has always been a public health mitigation option, with substantial social and economic cost and uncertain effects on outbreak control.

Smart Applications on Cloud

Cloud computing is a new deployment and operational model in which high level computation services and storage are provided by Internet ("cloud"). In this project we investigate how applications can become smarter and take advantage of many features that clouds provide.

Variation in Hospital Resource Use: Systemic Predictors and Implications on Quality and Value

Research Project Vision: To promote attention to quality, appropriateness and accountability in hospital resource use.
This vision is underpinned by the following four strategies:
1. Establish resource use variation reports specific to departments and individual providers.
2. Associate resource use with quality outcomes that measure accessible, effective, safe, efficient and appropriate care.

Self-Centering Concrete Structures

Recent major seismic events, including the 2011 New Zealand Earthquake and the 2010 Chile Earthquake, have demonstrated similar trends to previous earthquakes; that current state-of-the-art seismic design codes ensure, for the most part, that loss of life is avoided. It is accepted in the engineering community that significant damage can be expected for major earthquakes. However, building officials and owners are not aware that many structures will not be serviceable after a major earthquake, resulting in significant economic consequences.

Global Innovators: Broadcasting to Digital Technologies

This position supports a research project on the changes in the communication technologies from broadcasting to digital technologies by examining the global innovators. This work will investigate the core elements of the people who were at the centre of the last century of communication technologies’ transformation. This research will focus on the catalysts of conversion from one medium to the next from broadcasting to the various visual technologies to the modern-day users of the all-encompassing digital technologies.

Protesting Poverty: Mediated Global Protest and Images of Poverty

This position supports a research project concerning the representation of poverty in Western consumer society.

Postcard from Mexico: why galaxies spin

Most previous studies of spin in real galaxies were done in 2-D, so Dr. McCall’s study has changed the discussion of galaxy spins in the astrophysics community. This spin organization is at odds with established theories of spin alignment in our “neighbourhood of galaxies”. Understanding spin alignment provides insight into how this neighbourhood emerged and evolved.

2015 Mitacs PhD Award for Outstanding Innovation: George Conidis, York University

George Conidis, a PhD student in the Department of Physics and Astronomy at York University is the recipient of the Mitacs PhD Award for Outstanding Innovation for his research at Universidad Nacional Autónoma de México with Dr. Michael Richer through a Mitacs Globalink Research Award.

The Evolving Legal Services Research Project, Stage II

How can public legal education and information help Canadians get justice in our legal system? With the demand for publicly-funded or low-cost legal services far exceeding the supply, public legal education and information (PLEI) is filling an increasingly larger role in meeting the legal needs of people with modest means. Yet we know relatively little about how PLEI can help people deal with their legal problems. examines the effectiveness of PLEI in helping low- and modest-income people address their legal problems.