Évaluation in silico d’une prothèse d’épaule innovante pour maximiser la mobilité des patients

Actuellement les prothèses d’épaules dites inversées sont préconisées dans le cas de coiffe des rotateurs endommagée. Ces prothèses assurent la stabilité de l’articulation mais limitent la mobilité articulaire, notamment en élévation du bras. Pour pallier cette déficience, Statera Medical propose un design de prothèse innovant avec un degré de liberté additionnel. En collaboration avec le laboratoire de simulation et modélisation du mouvement, cette nouvelle prothèse sera testée puis optimisée par des simulations musculosquelettiques.

Développement d’un exosquelette pour les travailleurs de la construction afin de réduire les efforts au tronc et aux épaules

Les blessures ou lésions au travail constituent la 2e cause la plus importante d’invalidité au monde. Afin d’aider les travailleurs dans leurs tâches et réduire l’exposition aux blessures, l’utilisation d’exosquelettes est une avenue prometteuse. Il existe déjà plusieurs exosquelettes d’assistance pour la production automobile et les industries manufacturières, mais ceux-ci ne sont pas adaptés aux travailleurs de la construction.

Evaluation of a radiomic approach based on hyperspectral retinal imaging to predict the cerebral amyloid status for the diagnosis of Alzheimer’s disease

The project will help Optina validate and further develope a novel technology to predict the presence of significant amyloid (A?) deposition in the brain from a simple, non-invasive hyperspectral retina scan in combination with an artificial intelligence algorithm. Accumulation of A? plaques in the brain is a key hallmark of Alzheimer’s disease (AD), but current methods to evaluate its presence in vivo (A? positron emission tomography imaging and quantification of A?

Tuning in to emotions of non-communicative persons

Many individuals who have severe disabilities or who have suffered traumatic injury are unable to move or speak, and hence, unable to communicate with their family and caregivers. The physiological systems of these individuals are typically functional and can change to reflect the unexpressed mental and emotional states of these otherwise non-communicative persons. In this project, we will design an exhibit which will collect data to generate an emotion classifier using changes in autonomic nervous system signals patterns.

Implantation et validation d’une nouvelle approche de navigation chirurgicale en chirurgie orthopédique

Malgré la précision inhérente des éléments matériels des systèmes de navigation chirurgicale existants, la façon dont ils sont couramment utilisés en chirurgie orthopédique introduit une imprécision en limitant l'intérêt clinique. Les chirurgies pratiquées comportent des étapes importantes pouvant bénéficier d'un guidage fiable et reproductible pour leur réalisation afin d'en optimiser le résultat, entre autres en rétablissant une fonction articulaire plus proche de celle d'une articulation en santé.

DLVR Drug Delivery Characterization

Highly targeted therapies can be devised to treat a variety of cancers, specifically acting on the mutated genes causing tumor growth. One challenge with such techniques is delivering the therapy to the interior of the cancer cell, when enzymes in the blood can actively break down the therapeutic molecules or when delivery to healthy cells can cause toxicity. Nanoparticle carrier molecules can solve this problem by containing the payload and delivering it directly to the cancer cell.

Optimization of a Dermoskeleton for Human Performance in Clinical and Occupational Applications

Physical disability in Canadian adults is largely due to painful mobility impairments, with the most common cause being diseases of, and injuries to, the musculoskeletal system and connective tissues (MSK disorders). MSK disorders are generally associated with natural aging, but are also caused by occupational injuries as well as brain or spinal cord injury or disease. The cost of these conditions to the Canadian Health Care system is in the tens of billions per year.

Testing of Fibre Properties for their Biomedical Applicability

Natural fibres have been used in many industry sectors such as automobiles, aerospace, construction, etc., but their use in the biomedical industry is relatively new. The major obstacle to their use is the lack of information on relevant fibre properties. This project focuses on testing three critical properties: antimicrobial properties, antioxidant properties, and water sorption in flax, hemp, canola, and sweet clover fibres. Testing these properties will be a stepping stone for proving the applicability of natural fibres in biomedical applications.

Systems and methods for planning and guidance ofneurosurgical procedures

Synaptive Medical Inc together with researchers at Western University, are developing a new Magnetic Resonance Imaging (MRI) platform customizersd for clinical neuroimaging. This proposal is to fund a range of student and post-doctoral training activities associated with the development and testing of this new system. The program will also support the development and testing of MRI-compatible devices and technology for use with the new platform.

Reducing daytime leg fluid accumulation using electrical stimulation of the legs to decrease overnight rostral fluid shift and consequent sleep apnea

Obstructive sleep apnea (OSA) is a common disorder affecting 6% of the adult population and increases risk of cardiovascular mortality. OSA occurs due to repeated full or partial collapse of the upper airway during sleep. One contributor to airway collapse during sleep is the overnight shift of fluid from the legs towards the neck where it accumulates. Increased daytime fluid accumulation in the legs magnifies this, resulting in more fluid accumulation in the neck and increased OSA severity.