Targeted delivery of drugs can reduce the side effects associated with oral delivery systems. The urethra provides easy access of therapeutic agents to the urinary bladder, an ideal organ for localized therapy for the treatment of bladder cancer, interstitial cystitis, overactive bladder, and chronic prostatitis. We propose a new therapeutic approach to increase the residency time and efficacy of the drugs by using biogradable polymers as a drug carrier, allowing a prolonged release of drugs in the bladder.
Wind turbine generator power output and consumer electricity demand vary independently from one another. This presents a difficult situation for electricity grid managers as they attempt to exactly match demand using wind turbines and conventional generators (e.g. hydro, fossil fuels). Accurate forecasting of wind turbine generator power enhances management of the electricity grid, allowing for more wind turbine generating capacity while maintaining grid stability.
The overall research aims at conducting studies that use high volume data and analytics in order to provide realtime process optimization and optimal control to processes that are to be controlled in preparation for the industrial environment. These investigations is the first stage or Phase 1 associated with creating the mechanism to have machines learn, learn form each other and make intelligent decisions, using a framework of sensor(s) connectivity and cloud-based computing as part of the industrial internet.
The project relates to the fabrication of polymeric devices capable of mimicking that of live human tissue under x-ray computed tomographic (CT) imaging. These devices must be fabricated in such a way that specific material properties are controlled to thereby precisely mimic the desired tissue. The work following this will benefit the partner organization as they will be able to optimize CT imaging conditions by means of precise tissue mimicking polymeric devices.
In this collaborative project with Comtek Advanced Structures, the PhD Intern will develop methodologies to model and predict the propagation of acousto-ultrasonic and ultrasonic sound waves in advanced composite materials for aerospace applications. These sound waves can be used to detect damage and degradation in aircraft structures.
From the survey of literature (Eames et al. (1995), Chunnanond & Aphornratana (2004b), Chunnanond & Aphornratana (2004a) and others), the performance of a jet refrigeration system depends greatly on the ejector configuration (characteristics). Many researchers have shown the need to improve performance in order to make ejector-based cooling economically more attractive.
Temperature control is very important to a modern day society. Certain beverages, such as soda pop, alcoholic beverages, and even water are refrigerated so that they are more refreshing to drink. This project objective is to design novel environmentally benign and emission-free self-cooling beverage cans. Two different systems with different cooling approached are considered. The first system is built on chemical reaction that does not evolve any harm output that the user will be exposed to, and the other system uses the physical principle of cooling with expansion and absorption.
Airlines take the extra effort required to figure out what is the best route that their aircrafts should take so as to minimize additional costs from non-revenue flights or idle time. One way to di this is to first generate large numbers of feasible routes and then assign flights to a subset of them so as to cover all flight legs. It is clear that the quality of the resulting solution depends highly on both the number of routes we generate anf also the diversity among the routes.
Près de 98 % de l’énergie électrique québécoise provient de l’hydro-électricité, une source d’énergie propre et renouvelable. Il apparaît donc important d’utiliser au mieux cette énergie. Dans cette optique, le Québec devrait favoriser l’utilisation de pompes à chaleur qui possèdent des performances supérieures à celles des plinthes électriques. Leurs performances sont toutefois affectées à mesure que la température extérieure diminue.
Tailings produced by oil sands mining operations are a long-term liability. Separation of water from fine solids is a critical operational and environmental challenge for tailings management and reclamation. Current methods have ongoing challenges to meet geotechnical performance criteria, and require expensive processes and movement of very large amounts of fluids and solids. Electrokinetic Solutions (EKS) has developed a process for electrical stimulation of oil sands tailings that dewaters and strengthens the resulting soil with simple electrodes and no moving parts.