Since 1990, the CIHR Canadian HIV Clinical Trials Network (CTN) has advanced research to prevent, treat and manage human immunodeficiency virus (HIV), aiming to develop a cure for this disease. Over these 30 years, many clinical and research projects have been funded, generating important information and considerable data related to HIV. However, this relevant knowledge has not been organized in a central resource and shared effectively with the scientific and patient community hindering accessibility of the generated data elements and any insights from their combined analysis.