Development of a neural network algorithm to quantify chronic osteoarthritic pain in rats - Year two

The progression of pain research has been limited because of the overreliance on nociceptive assessment tools. These nociceptive assessment tools only assess the sensory component of pain and neglect its emotional component. It has been suggested that behavioural tools, such as the grimace scales, can assess the emotional component of pain. The use of various molecular markers are also promising new avenues to assess pain in various experimental models. The concurrent use of all three types of assessment methods will build a more accurate and complete picture of pain.

Development of a neural network algorithm to quantify chronic osteoarthritic pain in rats

The progression of pain research has been limited because of the overreliance on nociceptive assessment tools. These nociceptive assessment tools only assess the sensory component of pain and neglect its emotional component. It has been suggested that behavioural tools, such as the grimace scales, can assess the emotional component of pain. The use of various molecular markers are also promising new avenues to assess pain in various experimental models. The concurrent use of all three types of assessment methods will build a more accurate and complete picture of pain.

Développement et validation de nouvelles cibles épigénétiques de la douleur chronique chez l'animal arthrosique

La douleur arthrosique est la première cause de morbidité et de douleur chronique dans nos sociétés occidentales, source de pertes économiques et de productivité énormes. L'arthrose est aussi la maladie dégénérative la plus commune chez les animaux de compagnie et un sujet de consultation vétérinaire fréquent. Malgré des analyses extensives, l'origine et le développement de cette douleur demeurent mal compris. Ce projet de stage post-doctoral en partenariat entre ArthroLab Inc.