Gold Nanoparticle based Biosensor to detect viral RNA in vitro by colorimetry

The proposed project involves COVID-19 detection using solution of gold nanoparticles. Upon detection, the gold solution changes its color from red to blue. The solution contains gold nanoparticles with biomolecules that can detect SARS-Cov-2 virus genome that causes COVID-19. The first step is to take saliva sample from the patient and put it inside the first red solution. Then second amplification solution (which contains displacer and linker) is added to enhance the blue color and it increases the sensitivity of the detection.