Extraction, isolation and identification of activemolecules in Kisameet Clay

Initial studies on the Kisameet Bay Clay Deposit by Dr. Ernest Hauser of MIT in the early 1950's showed the unique properties of this clay deposit. To build on this early research and make clear a distinction between Kisolite and other clays on the market, we have chosen to invest in modern research. As such, a research intern from the University of British Columbia will use and evolve modern chemical characterization techniques to isolate and identify the biologically active (i.e. antimicrobial) organic components of Kisolite.

Characterization, antibacterial mechanism and improvement of Kisolite Clay

Kisolite Clay, a unique BC clay, has been found to have healing properties for skin irritation and internal ailments. However, this clay is not well understood in terms of its chemical and physical properties and the mechanism underlying its antibacterial properties. During preliminary tests it was found that the pH and oxidation state of the Kisolite clay changed over time. The impact of these changes on antibacterial properties will be investigated.

Refining of Kisolite Clay for Cosmetic and Phamaceutical Applications

There are four main objectives for the proposed project: 

 

(1) To investigate three techniques of aiding the wet screening process including: (a) inclined screening combined with water jets, (b) sonication, and (c) a combination of those two techniques, to find optimum operating conditions for each technique and allow them to be evaluated and compared.

(2) To implement the most suitable technique on the industrial scale and establish its optimum operating conditions.

"The mechanism(s) of antimicrobial activity of Kisameet clay

Kisameet Clay is a First Nations product of great interest due to its potent antimicrobial activity. Investigation of KC, as a potent inhibitor of bacterial and yeast growth, shows promise as a therapeutic agent. Work is in progress to identify the chemical components of KC responsible for this therapeutic activity. Work is in progress to identify the active substances. We are collaborating with experts in the study of clay-like materials to ascertain the role of metal ion interactions in the antibacterial property.