Development of LBT-1 as an alternative technology to antibiotic molecules

Antibiotic resistant bacteria are one of the major threats of the 21st century. These superbugs, which are resistant to virtually all our antibiotic arsenal, turns benign infections, such as urinary tract infections, into life threatening diseases. It is estimated that, by 2050, 10 million people will die each year because of antibiotic resistance. We thus need to develop alternative technologies to conventional antibiotics in order to prevent this scenario from unfolding.
This project proposes a totally new approach to eliminate antibiotic resistant bacteria. Instead of using molecules to kill bacteria, we propose to use engineered probiotics capable of recognizing and eliminating specifically antibiotic resistant bacteria. This therapeutic breakthrough approach turns superbugs into regular bugs that we can eliminate.

Vincent Baby
Superviseur universitaire: 
Sebastien Rodrigue
Partner University: