Synergistic actions of nutraceuticals on pain and inflammation in experimental arthritis
Arthritis is among the most common chronic conditions in Canada in both children and adults. Arthritis is a potentially disabling disease causing joint inflammation and pain. Increasingly, people suffering from arthritis are using alternative therapies including nutraceuticals. This research aims to create new knowledge about the synergistic effects of gamma-linoleic acid (GLA), eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) with and without boswellia serrate extract to improve pain and inflammation in models of juvenile and adult arthritis. Our research, by studying the mechanisms and key factors that produce pain associated with inflammation in arthritis, will provide scientific evidence for the efficacy of these unique nutraceutical combinations in these two differing age groups to improve care and outcomes in arthritis.