Impact of microparticles in cancer progression

Blood platelets are the principal source of cells known to shed small extracellular vesicles which package biologically active molecules. We have recently identified a new type of these vesicles (called microparticles/MPs) that contain mitochondria, which represent the energy producing motors for living cells. We have also discovered that MPs preferentially bind and internalize into leukemia cells to transfer their contents. As a result, recipient cancer cells gain energy producing capacity, which leads to increased cancer processes.

Named Entity Recognition (NER) autodetection and Adverse Events (AEs) prediction from Social Media and scientific journals using a Deep Learning approach

Social medias data bases are important for continuous and automated Adverse Drug Reactions (ADRs) surveillance. Predicting ADRs can reduce the related mortality. A systematic review of the medical scientific literature is required for tracking and identifying the risk/benefit ratio of drugs and safety issues.
The implementation of means of standardizing patient’s language used in social media such as Twitter will improve the precision of ADR detection and continuous surveillance at post-marketing phase of drugs (off-label drug uses included).

Incorporation de la lignine dans la formulation d’une peinture à base d’eau

La protection de l'environnement et la préservation de la santé occupent une place de plus en plus importante dans les préoccupations de la société de consommation et de ce fait, dans le monde industriel.
Les gens souhaitent utiliser pour leur logement des produits plus respectueux de l’environnement.

Analyse critique des connaissances issues de la recherche en langue française portant sur les élèves en situation handicap qui présentent des troubles spécifiques d’apprentissage du primaire au postsecondaire depuis les 15 dernières années

On estime que les troubles d’apprentissage spécifiques (TAS) touchent entre 5 et 15% des élèves (APA, 2013). Pour les enseignants et les orthopédagogues, un des défis qui se pose dans l’intervention auprès de ces élèves est celui de l’utilisation des données pertinentes de la recherche. On ne dispose actuellement pas d’outil permettrait de dresser un portrait ou de distinguer les textes pertinents des autres pour soutenir l’intervention auprès des élèves qui présentent un TAS.

Étude sur l’impact du niveau de risque en cybersécurité des PME du Québec suite à la transformation numérique post-covid et développement d’un algorithme de gestion du risque

L'objectif principal de cette recherche est de déterminer le niveau actuel de risque électronique dans les PME. (10 à 499 employés) et d'étudier les variables qui peuvent influencer la probabilité et l'impact de l'e-risque dans le futur.

Developing biosensors for rapid detection of precious metals as well as heavy metals

Heavy metals can be found in diverse consumables like foods, cannabis,cosmetics, drinking water and so detection and identification of their concentration is an important concern for public health. Each country has its own regulations for permitted concentration which are considered as harmless for public health. The high concentration of heavy metals can cause several damages and causes toxicity for adults and children. Rapid detection of these molecules so is very important for industries and governmental organizations.

IL-1-dependent ncRNA-based-therapy approach to enhance the bioactivity of endothelial progenitor cells in ischemic retinopathy: a new vasoprotective strategy

Retinopathy of prematurity (ROP) is the leading cause of blindness in premature neonates. ROP is associated with inflammation largely mediated trough interleukin (IL-1), which triggers an initial critical phase of ocular vascular degeneration. ROP is also an excellent model of ischemic retinopathies in general. The formation of new blood vessels after tissue ischemia is not only restricted to local endothelial cell proliferation, but lately shown to involve endothelial progenitor cells (EPCs) capable of forming a neovascular network on their own.

Les incidences de la pandémie sur l'État de droit du point de vue de la garantie des droits économiques, sociaux et culturels des migrants: approche comparée au regard du droit interne et du droit international

Le projet a pour objet l'étude des conséquences de la pandémie sur la garantie des droits économiques, sociaux et culturels des migrants en situation de mobilité, volontaire ou contrainte, pour des motifs économiques ou des considérations d’ordre humanitaire.
Le contexte d'urgence sanitaire à l'échelle mondiale a conduit de nombreux gouvernements à adopter des mesures d'exception.

Development of machine learning and artificial intelligence based tools to improve efficiency in financial services - Year two

Our interactions with actors in the financial services industry, including our partner company, uncovered that they possess large amounts of data pertaining to investors and markets, but have yet to extract/learn information of significant value from that data such as expected actions by clients. The industry is conscious of this, but while they are making the needful investments in IT, they report lack of academic expertise in machine learning (ML) / artificial intelligence (AI) to unlock full potentials of such investments.

BIM (Building Information Modelling) and Supply Chain Planning inConstruction

In this project, we will consider construction supply chain management SCM within the context of BIM. The objective is to provide an automated BIM-based platform for construction supply chain planning. Using automatic data extraction from a BIM file, we will develop sophisticated supply chain optimization models that fit the reality of construction projects. Here, the critical decisions for CSC planning (strategic, tactical) are conducted in the early phase of planning based on data provided by BIM.

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