Development of a multiscale Monte Carlo based treatment planning system for patient specific dosimetry (DaRT-TPS)

With this proposal a software will be developed to enable delivery of a maximum amout of radiation to the tumour while sparing healthy tissues. This will benefit Canadian cancer patients as well as highly qualified personnel that will be trained in an interdisciplinary environment,

The development of an artificial intelligence-based platform to improve thecharacterization and the identification of unstable atherosclerotic plaques

Heart attacks and strokes are the leading causes of death and disability in the world. They are caused by the rupture of dangerous fatty deposits, called plaques, that build up in the arteries of the neck and heart. The only current method to identify whether a person is at risk of having a heart attack or stroke is to measure the narrowing of the artery caused by the plaque. However, this method is insufficient and leads to misdiagnosis or inappropriate treatment allocation.

Development of a Proof of Concept for a System to Increase Success Rates of Organ Transplant and Donation Matches

Transplantation is the preferred treatment for patients whose kidneys have failed. There is an ever-growing gap between patients in need for a transplant and available donors. In response to this need, there has been an increase transplantation of donors who experienced circulatory determined death (DCD). However, many potential DCD donors fail to end up in transplantation.

Plant-based virucidal coatings for protective masks

The role of PPE in saving countless millions of lives of have been somewhat taken for granted because they are ubiquitous and relatively simple, leading them to be neglected as an active research area. There is limited personal protective equipment that have been developed to effectively protect against viruses in relatively fast contact times. Protective mask filtration is generally accepted to vastly reduce transmission but do not effectively inactivate viruses, and specialized coatings are needed in order to ensure viral inactivation to limit contamination within healthcare workflows.

Identifying and Prioritizing Difficult Systemic Sclerosis Health Care Decisions to Inform the Development of Patient Decision Aids

When faced with complicated treatment decisions, patients and health care providers can use patient decision aids to gain information about options and potential outcomes. Treatment for rare autoimmune diseases like systemic sclerosis can be overwhelming as there may be more than one treatment option, without one being clearly better than another.

Des crises humanitaires aux pandémies : la technologie à la rescousse

Qui aurait pu prévoir que les actions humanitaires lors du séisme de 2010 en Haïti viendraient éclairer, 10 ans plus tard, les démarches de chercheurs, d’entrepreneurs et de stagiaires Mitacs dans la crise de la COVID-19?

Lors de son déploiement au sein d’un hôpital de campagne de la Croix-Rouge après le tremblement de terre, le Dr Abdo Shabah voit le potentiel d’une utilisation accrue des technologies pour réussir des interventions d’urgence en santé.

Un bracelet spécial de surveillance à la COVID-19 et de suivi de contacts

Depuis le 27 juillet 2020, le nombre de cas de COVID-19 confirmés à travers le monde a atteint 16,3 millions de personnes, dont 114 000 cas au Canada. Entre deux et huit pour cent des cas de COVID-19 comportent des symptômes sévères qui mènent à la détresse respiratoire, à la défaillance des organes et même à la mort. Actuellement, les suivis médicaux réguliers se composent d’appels téléphoniques individuels afin de contrôler les signes vitaux du patient à distance.

Medical cannabis and cancer: A qualitative exploration.

In recent years Medical Cannabis (MC) has become a much discussed and ever-evolving topic in Canada. A growing number of studies have highlighted the medical and multidimensional benefits of cannabis. The question of the spiritual benefits of MC forms part of this holistic approach. Qualitative research on medical cannabis is limited, and most of it has explored the experiences of people who took cannabis illegally.

The Cellular Role of Double-Stranded Break Repair Protein, Endo-exonuclease (Trmt2a,b), in Cancer Therapy and in Inflammatory Response

This project aims at understanding the role at a cellular level, of a protein called Trmt2a,b in the repair of DNA in the context of cancer and inflammation. We will study a particular set of blood samples obtained from a cohort of patients affected by acute lymphoblastic leukemia (ALL), a form of blood cancer, where some of these patients will also develop a complication in the form of bone death, called osteonecrosis (inflammation).

Les microplastiques et contaminants associés dans l’estuaire et le golfe du Saint-Laurent : caractérisation environnementale, sociale et bioaccumulation ou dépuration chez les bivalves

Ce projet propose de définir les enjeux socio-environnementaux et socio-économiques reliés à la présence de microplastiques (MP) marins dans l’estuaire et le golfe du Saint-Laurent, une région hydrologique complexe sous-étudiée vis-à-vis cette problématique. Ceci permettra d’orienter les décisions visant à protéger l’environnement tout en soutenant les secteurs maritimes, notamment ceux reliés aux ressources marines commerciales. Ainsi, ce projet intersectoriel, multipartenaire et innovant a pour but d’étudier :