Sounding Out the “Early” Applicability of Health Economics (HE) and Health Technology Assessment (HTA) Considerations in the Drug Development Process

With the imminent emergence of personalized medicine and the availability of costly targeted drugs comes the crucial allocation of ressources within the halthcare systems. Determining which treatment options should be funded has become an increasingly difficult task. Decision-makers are relying heavily on pharmacoeconomic (PE) evalutions to decide which of them will be most effective and safe—but also, which will most improve the quality of life of patients and which will be most valued by society.

Travailler dans le mouvement communautaire autonome à l’ère de la COVID-19 : analyse des conditions de travail

Le mouvement communautaire autonome a été au cœur de la réponse gouvernementale durant la pandémie de la COVID-19. Que ce soit pour répondre aux besoins des personnes en situation d’itinérance, d’assurer la sécurité des femmes victimes de violences conjugales ou encore pour assurer la sécurité alimentaire des personnes affectées par des pertes d’emploi, les organismes communautaires sont intervenus pour répondre aux besoins émergeant de la population et des personnes les plus vulnérables.

Calcul de dose pour la curiethérapie par diffusion d’émetteur alpha.

La curiethérapie est une technique de traitement de tumeur cancéreuse qui vise à insérer des grains radioactifs dans la tumeur ou très près de celle-ci, pour livrer une dose de rayonnement élevée dans le volume-cible tout en réduisant la dose aux tissus sains environnants. La technique de curiethérapie par particule alpha est sur le point de révolutionner le domaine, car elle offre une efficacité radio-biologique plus élevée pour le traitement de la tumeur, couplée à une réduction des effets secondaires.

La médiation muséale numérique, une dynamique d'intervention favorisant le sentiment d’appartenance sociale.

Encadrée par la Chaire de recherche du Canada en muséologie citoyenne, cette étude vise à comprendre le potentiel et les limites d’une application mobile qui encourage la prise de parole des groupes racisés autour d’objets de la collection ethnographique déployés dans l’aile des Arts du Toute-Monde au Musée des beaux-arts de Montréal. Son originalité repose sur l’application pratique des théories décoloniales, permettant d’identifier les facteurs qui font des initiatives numériques d’inclusion un vecteur du développent du sentiment d’appartenance sociale des citoyens.

iPSC derived 3D muscle engineering

Myopathies are a group of muscle diseases that are caused by over 150 genes variants, leading to muscle weakness and/or wasting. In addition to the emotional, physical and social impact on the patients and their families, the medical expenditure for the patients affected by myopathies is substantial, about $7.2 billion in Canada, which makes it the 4th diagnostic category with the largest total cost for the healthcare system.

Adaptive navigation in structured archives of immersive content

In the 1990s, game companies started releasing the first prototypes of virtual reality headsets. Since then, virtual reality evolved into a wide variety of practices and experiences. The field of possibilities extends from 360-degree immersive films, where the frame of vision and hearing can vary with a head turn, to highly interactive game-based works, where the user can move in the virtual world to perform decisions that will change the course of the story.

Predicting demand and inventory shortages for better inventory management in health care institutions

This project aims to predict demand and inventory shortages for better inventory management in health care institutions. This will initially allow for a reduction in the expenses generated by emergency orders placed during a stock shortage. Indeed, it will be possible for the establishment to order a larger quantity of the product from the supplier or to place an order with another supplier.

Crop metabolomic strategies enabling phytoremediation of contaminated soils

High tolerance plants generate a complex and largely unexplored toolkit of secondary metabolites to manipulate soil contamination. Understanding these biochemical mechanisms could reveal potential pathways by which polluted soils could by rejuvenated, but assessment of root exuded metabolites is currently technically challenging and secondary metabolite content in the biomass of leading phytoremediation crops is still yet to be explored in detail using advanced metabolomics.

Few-Shot Object Segmentation

Computer vision researchers have been moving beyond simple image classification and tackling more complex tasks such as object localization, detection and semantic segmentation. However, many of the proposed methods require large amounts of annotated data such as segmentation masks, which are expensive and time-consuming to acquire. Moreover, those methods cannot segment new object categories which were not present in the training set.

Few-shot segmentation alleviates both those problems by learning end-to-end to segment new object categories from few examples.

Market making for digital assets

Market makers facilitate trading in electronic financial markets by simultaneously offering to buy and sell the same asset at any given time. Their role is to provide price stability and increase market liquidity to improve its overall efficiency. Digital assets markets are extremely fragmented and present both challenges and opportunities for market makers. These latter must offer participants accurate prices while balancing their asset inventory on many venues at the same time, what represents a difficult synchronization task.