Genetic Susceptibility to Air Pollution Health Effects in Children

Air pollution threatens global human health, with children being uniquely vulnerable due to their actively developing respiratory and neurological systems. Exposure to higher levels of air pollution is linked to asthma, reduced lung function, exacerbation of pre-existing respiratory symptoms, and impaired neurobehavioural health outcomes. Canada’s record-breaking wildfire seasons have intensified air pollution health concerns. While reducing exposures and protecting youth from the harmful effects of air pollution remains crucial, understanding the variability as to why some children may be affected more than others is equally important. This research aims to understand how air pollution exposure, with a focus on wildfire smoke PM2.5, affects children’s lung and brain health, including how genetic susceptibility causes variable responses.

Faculty Supervisor:

Emily Brigham

Student:

Partner:

Legacy for Airway Health

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

The University of British Columbia

Program:

Accelerate

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