Impact of a probiotic supplement on the intestinal microbiota of veal calves

The intestinal microbiota is essential for enhanced gut health. Factors such as diet transition and the stress of transportation are associated with changes in the normal microbiota of calves. In addition, specific microbiota profiles have been associated with better performance and used to predict diarrhea in calves. Improved performance can be achieved by the use of feed additives, but its mechanisms of action are not completely understood. This study aims to investigate the impact of a blend of probiotics on the intestinal microbiota of veal calves. To do that, 50 Holstein calves arriving to a veal unit will be divided in 2 groups (treatment and controls). The supplement will be administered during the 2 first days after arrival. Fecal samples will be collected before supplementation (D0), and at days D4, D14 and D30. Blood samples will be taken at D0 and D4 for cytokines, cortisol and haptoglobin levels and body weight will be measured on D30. Next generation DNA sequencing will be used for microbiota characterization to investigate the potential of the additive to enhance beneficial bacteria and control stress-related imbalances. Associations with stress, performance and severity of diarrhea will be investigated

Faculty Supervisor:

Marcio Costa

Student:

Partner:

Probiotech International Inc

Discipline:

Life Sciences

Sector:

Agriculture; Manufacturing

University:

Université de Montréal

Program: