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Sequential Ring Opening and Radical Atom Fragmentation Transfer Polymerization to Generate Block Copolymers for Specific Organ Targeting of Polymer Nanoparticles
Polymeric nanoparticles fail to achieve selective organ distribution. We hypothesize that alike lipid nanoparticles, varying the physico-chemical properties of the nanoparticle surface could lead to specific organ targeting. In this regard, we are interested in mapping out the biodistribution caracteristics of nanoparticles with hydrophilic surfaces of various polymer lengths. Therefore, we are synthesizing a polymer library by sequential ROP and RAFT polymerization which will be screened for these desirable properties. The proposed internship in Jena, Germany will provide me technical skills which will expedite my project in Montreal.
Faculty Supervisor:
Xavier Banquy
Student:
Partner:
Friedrich-Schiller-Universität Jena
Discipline:
Engineering
Sector:
Education
University:
Université de Montréal
Program:
Globalink Research Award
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Mitacs is funded by the Government of Canada, the Government of Alberta, the Government of British Columbia, Research Manitoba, the Government of New Brunswick, the Government of Newfoundland and Labrador, the Government of Nova Scotia, the Government of Ontario, Innovation PEI, the Government of Quebec, the Government of Saskatchewan, and the Government of Yukon.