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Projets par catégorie

Health Technology Assessment: The impact of clinician input on drug funding decisions

CADTH’s recommendations are based on clinical and economic evidence which assist in making an informed decision on the optimal use of health technologies3. However, this evidence does not always evaluate outcomes that patients and physicians deem important. By incorporating patient and clinician input, the clinical and practice perspectives of the unmet need are becoming reflective of the current reality.
The findings of a targeted literature search demonstrated high levels of clinician engagement in oncology since 2016. However, for the newly implemented process of incorporating clinician input in non-oncology drug funding decisions, the levels of engagement have been very limited2.
To determine the impact of clinician input on drug funding decisions, an analysis of the drug funding recommendations in both oncology and non-oncology will be conducted to quantify the levels of engagement and qualify the impact of clinician input on different categorized parameters.
A comparative analysis will determine if there is an association between the CADTH and NICE’s procedure to the level of engagement and impact of clinician input. With the collected data, potential tactics to increase awareness for clinician engagement will be suggested.

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Superviseur du corps professoral :

Marc Servant

Étudiant :

Partenaire :

Corporation AbbVie

Discipline :

Life Sciences

Secteur :

Manufacturing; Professional, scientific and technical services; Retail trade

Université :

Université de Montréal

Programme :

Accelerate

Développement de la stratégie d’intégration de l’approche géométallurgique : de la caractérisation des carottes de forage à la prédiction des comportements métallurgiques et environnementaux

Mines Agnico Eagle a investi massivement depuis 2020 dans la caractérisation automatisée des carottes de forage. L’application principale de cette caractérisation vise tout d’abord l’aide à l’identification des différents caractéristiques géologiques (lithologies, échantillonnage, structure, etc.) de manière systématique. D’après la littérature, l’outil de caractérisation automatisée pourrait être utilisé à des fins de prédiction des comportements métallurgiques et environnementaux. Le objectif de ce projet est de documenter les applications géométallurgiques et géoenvironnementales des caractérisations automatisées de carottes d’après la revue de littérature scientifique et technologique. L’accent sera mis sur les corrélations directes et indirectes des informations de la carottes avec les comportements mais aussi sur l’intégration de l’application dans les compagnies minières aurifères.

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Superviseur du corps professoral :

BenoÎt Plante;Bernard Giroux

Étudiant :

Partenaire :

Agnico Eagle Mines Limited

Discipline :

Earth science

Secteur :

Mining

Université :

Université du Québec en Abitibi-Témiscamingue

Programme :

Business Strategy Internship

Feasibility Study of Graph Modelling in the Treatment of Heart Failure

iClinic-HF is one of the specialized modules that is operating in the 12 heart failure (HF) clinics across British Columbia. The major challenge that these clinics face are the limitations and constraints in resources with regards to the staff and funding operating under constraints of a universal healthcare system environment. Further limitations of an effective provincial HF clinic network, and fixed capacity of each HF clinic, necessitates smart solutions to help all patients using specialized care as quickly as possible, minimizing cardiac complications, and maximizing their longevity. Guideline-directed medical therapy (GDMT) is the cornerstone to improving outcomes and reducing the burden of disease and cost. The potential for improving medication optimization can lead to clinical outcome improvements,2 augmentation of clinic capacities, as well as the possibility of developing a tool for commercial uses. Medication optimization requires multiple titrations in HF patients and therefore a collaborative team approach is needed between the healthcare providers. The sequence (i.e., order of GDMT including four classes of medications) of prescription could be different based on patient characteristics as well as the race at which a particular patient manage to be optimized (slow, standard and rapid optimizers).

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Superviseur du corps professoral :

Nathaniel Hawkins

Étudiant :

Partenaire :

iClinic Systems Inc.

Discipline :

Life Sciences

Secteur :

Manufacturing; Professional, scientific and technical services

Université :

The University of British Columbia

Programme :

Business Strategy Internship

Défis de l’utilisation de l’hydrogène vert dans le secteur du transport lourd routier au Québec

De par son rôle important dans l’économie québécoise, le transport de marchandise fait face, toutefois, à divers enjeux structurels pour répondre aux défis de la décarbonisation et doit explorer de nouvelles solutions de mobilité telles que les camions à hydrogène (H2) à piles à combustible. Certes, les véhicules électriques à batterie aient déjà montré leur avantage dans le transport routier intensif interurbain, cependant, aux vues des contraintes opérationnelles que pose le transport de marchandises, notamment les trajets de longue distance ou de lourdes charges à tracter, les camions H2 présentent des avantages significatifs pour assurer la décarbonation du secteur. Dans ce cadre, bien que certains pays en Europe et en Amérique du nord sont assez avancés dans leurs stratégies de décarbonisation du transport lourd, cela s’avère encore loin et différent en contexte québécois. Ce projet consiste à établir une revue de littérature internationale et l’adapter aux particularités et spécificités du cas québécois pour l’atteinte des objectifs établis en termes de réduction des émissions de GES et de carboneutralité.

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Superviseur du corps professoral :

Loïc Boulon

Étudiant :

Partenaire :

Propulsion Quebec

Discipline :

Engineering

Secteur :

Professional, scientific and technical services; Transportation and warehousing

Université :

Université du Québec à Trois-Rivières

Programme :

Business Strategy Internship

Boosting Performing Artists’ Careers for Recovery Post COVID

On Cue Performance Hub (OCPH) emerged in 2019 as a grassroots initiative to address challenges facing Regina artists trying to earn a living through their creative practice — even before COVID emerged. During the pandemic, retention of artists and earning a living wage in the performing arts has transitioned from a problem to a crisis. This cluster of internships strives to address this situation by setting up a series of programs, over the course of 10 – months aimed at providing professional training to the performing arts community in Regina in the form of workshops, internships and mentorships. In addition, interns will be brought on board the productions in our upcoming 2022/ 23 season to gain valuable experience through experiential learning opportunities, working with supervisors and well as tapping into the resources of On Cue’s senior participating arts companies, who will provide expertise in appropriate areas of production. At the same time, OCPH benefits by being able to present a season of creative work to Regina audiences.

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Superviseur du corps professoral :

Shannon Holmes;Ian Campbell;Ian Campbell;Shannon Holmes

Étudiant :

Partenaire :

On Cue Performance Hub

Discipline :

Sociology

Secteur :

Arts, entertainment and recreation

Université :

University of Regina

Programme :

Business Strategy Internship

Behavior of Concentrically and Eccentrically Loaded Hollow Circular Lightweight Self-Consolidating Concrete Columns Reinforced with Glass- and Basalt-FRP Bars and Spirals

To date, integrating fiber-reinforced polymer (FRP) bars as a valuable option as internal reinforcement for concrete members has gained significant interest in the construction industry, due to their corrosion resistance and high tensile strength-to-weight ratio. The use of hollow reinforced concrete (RC) columns (HCCs) instead of solid columns has increased in the construction of bridges with high elevations and long spans (e.g., bridge piers, bridge columns, and piles). The advantages that HCCs provide over solid columns with the same dimensions relate to enhanced structural efficiency (i.e., higher stiffness-to-weight and strength-to-weight ratios), which can be attributed to the decreased mass contribution of the columns to seismic response and to the lower amounts of concrete materials, thereby reducing costs. The incorporation of FRP reinforcement into hollow lightweight self-consolidating concrete (LWSCC) circular columns would significantly contribute to the production of lighter and more durable reinforced concrete (RC) structures. Large-scale hollow (LWSCC) circular columns will be tested under concentric and eccentric loads.

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Superviseur du corps professoral :

Brahim Benmokrane

Étudiant :

Partenaire :

Pultrall

Discipline :

Engineering

Secteur :

Construction and infrastructure; Manufacturing

Université :

Université de Sherbrooke

Programme :

Accelerate

An New Airframe Design Methodology for Safety-Critical UAV

Unmanned aerial vehicle (UAV) technologies have the potential to contribute to Canada’s resilience against climate and health crises and change people’s daily lives. Specific examples of use could be firefighting, land erosion mapping, the fast delivery of vaccines in the north of Canada, flying ambulances, defibrillators for emergency calls. These applications are challenging in many aspects. Two of the biggest challenges are reliability for safety and energy efficiency for competitive performance. Failures leading to an uncontrollable vehicle can cause catastrophic accidents if the vehicle collides with humans, aircraft, helicopters, or infrastructure. Therefore, safety-critical UAVs must be designed to minimize the probability of critical failures and maintain a safe operation if they occur. The airframe generally is the main contributor to the total mass of medium the size UAVs and thus a primary drivers of energy efficiency. Therefore, the emergence of UAVs for demanding applications will depend on the designers’ ability to optimize the UAV airframe early in the design process. The proposed research aims to develop a novel airframe design methodology. The novelty will be to include safety and reliability considerations in the conceptual design and integrate the methodology in a multidisciplinary framework for UAV design.

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Superviseur du corps professoral :

Jonathan Liscouet

Étudiant :

Partenaire :

Institut Supérieur de l'Aéronautique et de l'Espace

Discipline :

Engineering

Secteur :

Education

Université :

Concordia University

Programme :

Globalink Research Award

An Exploration of the Barriers and Facilitators to Access of Oral Health Care of Ukrainian Newcomers to Nova Scotia

The proposed research project will study the past and present oral health care knowledge and experiences of Ukrainians who have arrived in Nova Scotia, Canada since February 2022, due to the ongoing war in Ukraine. This will include an exploration of perceptions and knowledge of oral health, experience navigating oral health care services in Ukraine and Nova Scotia and identification of barriers and facilitators to accessing oral health care services. Utilizing a narrative qualitative methodology, in-depth, semi-structured interviews will be held with participants recruited through the Immigrant Services Association of Nova Scotia using a purposive sampling technique. The study is anticipated to provide insight into barriers and facilitators of access to oral health care services experienced by Ukrainian newcomers to Nova Scotia. Findings will help to inform oral health policy and practice with the goal of improving access to preventative and restorative oral health care services for Ukrainian refugees in Canada.

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Superviseur du corps professoral :

Heather Doucette

Étudiant :

Partenaire :

West Ukrainian National University

Discipline :

Life Sciences

Secteur :

Health and Related Sciences & Technology; Public Service, Policy, and Governance

Université :

Dalhousie University

Programme :

Globalink Research Award

Molecular Profiling and Spatiotemporal Analysis of Volatile Organic Compounds at Wastewater Treatment Facility

This project will employ a modern atmospheric testing instruments mobilized in a research purposed vehicle to make on-site and on-road measurements of air quality parameters with an emphasis on malodourous volatile organic compounds associated with the McLoughlin Point Wastewater Treatment facility and auxiliary services. This research will provide information that will profile emission sources within different process streams and assess the efficacy of abatement technologies on the facility site. On-road measurements will help identify potential impacts in the surrounding community as well as characterize other sources including those associated underground wastewater and residuals conveyance, industrial activities, transportation, and natural biological processes. The research will develop new data analysis tools to map odour compounds over time and space, improve odour abatement technology, and inform best practices for wastewater treatment operators.

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Superviseur du corps professoral :

Erik Krogh

Étudiant :

Partenaire :

Capital Regional District

Discipline :

Physics

Secteur :

Utilities

Université :

Vancouver Island University

Programme :

Accelerate

Tractography of the central olfactory pathway in prodromal Alzheimer’s disease

The diagnosis of Alzheimer’s disease is currently made when the criteria for dementia are met, i.e. when the cognitive deficits are severe enough to interfere with the person’s autonomy. Thus, it is important to find early markers of Alzheimer’s disease in order to be able to intervene before the dementia stage, in prodromal stages of the disease. Olfactory impairment may be an early marker of the disease, the impairment being present in the mild cognitive impairment stage, a stage between subjective cognitive decline and Alzheimer’s disease. On a neurological level, no study have evaluated the central olfactory pathway within the mild cognitive impairment stage of the disease.
The objective of the study is to compare the central olfactory pathway integrity between people within prodromal stages of Alzheimer’s disease and a healthy older adult group. This study will be the first to assess white matter integrity within central olfactory network within individuals at risk of developing AD. Our results could lead to the development of of new clinical tools for early detection of AD dementia that will combine behavioral measures (olfactory and memory tests) and neuroimaging measures (white matter integrity damage).

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Superviseur du corps professoral :

Johannes Frasnelli

Étudiant :

Partenaire :

Harvard Medical School

Discipline :

Life Sciences

Secteur :

Education

Université :

Université du Québec à Trois-Rivières

Programme :

Globalink Research Award

Development of sensors and interface electronics for consumer and industrial applications

Accelerometers are a type of sensor that have various applications from everyday handheld devices such as smart phones to complex systems such as airplanes. Sensors are devices that we use to “see”, “hear” or” sense” the environment around us. With accelerometers, we are measuring motions. When there is movement and as a result an acceleration is applied to a device, there is mass in the structure that moves, this movement can change some properties of the sensor; in this case, the capacitor on the device will change and with electronic interface we are measuring the change in the capacitance; Finally a current or voltage proportional to the applied acceleration will be produced, and we can use that output to determine the movement/position.

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Superviseur du corps professoral :

Behraad Bahreyni

Étudiant :

Partenaire :

CMC Microsystems

Discipline :

Engineering

Secteur :

Professional, scientific and technical services

Université :

Simon Fraser University

Programme :

Accelerate

Demande SSE | Mélina Béland – Évaluer les retombées environnementales de nos publicités

En soi, le projet sera axé sur la recherche et le développement puisque Mélina sera chargée d’analyser et évaluer les retombées environnementales de nos publicités. Le projet aura une grande valeur pour l’agence et nos clients. En effet, il s’agit clairement d’un volet sous-exploité qui viendrait compléter à merveille l’offre de service de notre département performance. La rigueur académique et l’accompagnement professoral fait également partie de l’approche du projet.

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Superviseur du corps professoral :

Sylvain Amoros

Étudiant :

Partenaire :

Click & Mortar

Discipline :

Business

Secteur :

Professional, scientific and technical services

Université :

HEC Montréal

Programme :

Business Strategy Internship