Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

30 508 projets complétés

2882
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5105
C.-B.
825
MB
681
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860
SK
9051
ON
9491
QC
97
PE
586
NB
1141
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Projets par catégorie

Exploring phosphonate biosynthetic capacity in anaerobic microorganisms

Molecules possessing a carbon-phosphorus bond (C-P) have traditionally been considered rare in Nature. For example, there are only ~50 phosphonate natural products known, although several have achieved commercial success (e.g. the antibiotic fosfomycin). In addition, several phosphonate cell surface modifications have been found over the last half century, but nothing is known regarding their biosynthesis or biological role. Interestingly, phosphonates possess a reduced (less oxidized) form of phosphorus relative to most biological phosphates, and it has long been suspected that phosphonates predominated in the low oxygen atmosphere of early Earth. We therefore hypothesize that modern day anaerobic environments represent a potentially rich source of phosphonates. To access this metabolic diversity, we propose to collaborate with Dr. Yihua Chen (IM-CAS Beijing), who recently developed a system to capture large fragments of DNA from anaerobic microorganisms and express their chemical output in a related anaerobic ‘host’ bacterium.

Voir la description complète du projet
Superviseur du corps professoral :

Geoff Horsman

Étudiant :

Partenaire :

University of Chinese Academy of Sciences (Institute of Microbiology)

Discipline :

Life Sciences

Secteur :

Biotechnology; Life Sciences (not health); Pharmaceuticals

Université :

Wilfrid Laurier University

Programme :

Globalink Research Award

Development of Input and Evaluation Criteria for a Video-Based Occupational Risk Assessment Tool

Workplace injury prevalence and cost have created an immediate need for ergonomics risk assessment tools that require minimal ergonomics training, rooted in a foundation of experimental research, and provide comprehensive outputs that give some indication of risk and required action. Observation-based tools have been widely implemented in practice due to their simplicity, accessibility, and cost- and time-efficiency, but they typically require specialized training, present inconsistent risk categories, and depend on user interpretation of a specific set of static posture and load parameters. MyAbilities Technologies Inc. has developed a video-based risk assessment tool (PDAi: Physical Demands Artificial Intelligence) that addresses these issues by using a task video recorded on a mobile phone and overlaying a set of digital joint locations to estimate physical demands and injury risk. The effect of video recording angle needs to be evaluated to guide users to record video that can maximize the accuracy of assessments results. Further, despite reaching being a prominent aspect of most occupational tasks, the effects of key task parameters – such as sitting vs. standing and one- vs two-handed reaching – are unknown, and need to be evaluated to provide accurate risk estimates related to reaching tasks for both practitioners and researchers.

Voir la description complète du projet
Superviseur du corps professoral :

Peter Keir

Étudiant :

Partenaire :

My Abilities Technologies;McMaster University

Discipline :

Physics

Secteur :

Health and Related Sciences & Technology; Biotechnology

Université :

McMaster University

Programme :

Elevate

Ultra-High Control Bandwidth Flying-Capacitor Converter – Design and Commissioning

For the realization of amplifiers with ultra-high control bandwidth, typically the series connection of high-frequency PWM H-bridges is considered in order to simultaneously achieve multi-level voltages and high effective switching frequency, which enables the required high cut-off frequency of the output filter and, thus, facilitates high control bandwidth. However, the approach is of high complexity, requires multiple isolated and bidirectional DC power supplies, which increase the overall size of the system, and, in addition, leads to elevated electromagnetic common-mode emissions that increase the filtering effort. Therefore, a realization based on the Flying-Capacitor Converter (FCC) topology is a promising candidate with regard to ultra-high control bandwidth. In order to clarify the advantages and disadvantages of both approaches, i.e., cascaded H-bridges and FCC, a research project in the context is proposed which should conceptualize, analyze and experimentally verify of an ultra-high bandwidth FC power converter.

Voir la description complète du projet
Superviseur du corps professoral :

Luiz Antonio Correa Lopes

Étudiant :

Partenaire :

Eidgenössische Technische Hochschule Zürich - dup

Discipline :

Engineering

Secteur :

Energy and Utilities; Technology; Automotive

Université :

Concordia University

Programme :

Globalink Research Award

Nutrition, Genetics and Athletic Performance – Year two

This project will result in the expansion of an athlete-focused genetic test to include additional genetic markers and algorithms for the purpose of personalized caffeine advice for endurance and other forms of exercise (strength, power, anaerobic-power) through continued analysis of 23 caffeine-associated genes that affect an athlete’s response to caffeine (positive, negative or no effect). The intern has already collected all necessary data, from over 100 athletes, from her previous doctoral research. She has already published some of her caffeine-associated findings. Other genes associated to body composition, dietary intakes and muscle physiology will also be investigated. Additional research in this area will directly benefit the partnering company, Nutrigenomix Inc., as developer of genetic tests for personalized sports nutrition available in 35 countries. The mission of Nutrigenomix is to maintain its position as one of the world’s leading providers and most trusted source of DNA-based nutrition information in a competitive marketplace. To achieve this goal, it is imperative that the company continues novel high-quality research to strength the quality of breadth of its products and services. TO BE CONT’D

Voir la description complète du projet
Superviseur du corps professoral :

John L Sievenpiper

Étudiant :

Partenaire :

Nutrigenomix Inc;University of Toronto

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Toronto

Programme :

Elevate

Nutrition, Genetics and Athletic Performance

This project will result in the expansion of an athlete-focused genetic test to include additional genetic markers and algorithms for the purpose of personalized caffeine advice for endurance and other forms of exercise (strength, power, anaerobic-power) through continued analysis of 23 caffeine-associated genes that affect an athlete’s response to caffeine (positive, negative or no effect). The intern has already collected all necessary data, from over 100 athletes, from her previous doctoral research. She has already published some of her caffeine-associated findings. Other genes associated to body composition, dietary intakes and muscle physiology will also be investigated. Additional research in this area will directly benefit the partnering company, Nutrigenomix Inc., as developer of genetic tests for personalized sports nutrition available in 35 countries. The mission of Nutrigenomix is to maintain its position as one of the world’s leading providers and most trusted source of DNA-based nutrition information in a competitive marketplace. To achieve this goal, it is imperative that the company continues novel high-quality research to strength the quality of breadth of its products and services. TO BE CONT’D

Voir la description complète du projet
Superviseur du corps professoral :

John L Sievenpiper

Étudiant :

Partenaire :

Nutrigenomix Inc;University of Toronto

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Toronto

Programme :

Elevate

Quand le patrimoine naturel rejoint le patrimoine culturel : les écosystèmes pyrophiles comme indicateurs d’activités humaines précoloniales au Bas-Saint-Laurent

Les feux naturels sont actuellement rares au Bas-Saint-Laurent et leur dynamique holocène demeure mal connue. Les écosystèmes pyrophiles exceptionnels, tels que les pinèdes, pourraient témoigner de feux naturels historiques. Les pins pourraient aussi avoir été favorisés par les activités humaines précoloniales. Les Autochtones, et notamment les Malécites, pourraient être impliqués dans le maintien de ces espèces. Ce projet vise à comprendre l’origine et la dynamique des pinèdes du BSL en relation avec les feux naturels et anthropiques. La corrélation spatiale entre la présence contemporaine de pinèdes et celle de sites archéologiques malécites sera testée grâce à une analyse cartographique (SIG). La présence de pinèdes de faible superficie sera vérifiée sur le terrain et dix d’entre elles seront sondées pour vérifier la présence de charbons et/ou vestiges. Les résultats du projet seront utilisés pour recommander d’identifier certaines pinèdes rares comme relevant de Forêts de Haute Valeur pour la Conservation (FHVC).

Voir la description complète du projet
Superviseur du corps professoral :

Guillaume de Lafontaine

Étudiant :

Partenaire :

Corporation de gestion de la certification forestière des territoires publics du Bas-Saint-Laurent

Discipline :

Life Sciences

Secteur :

Agriculture

Université :

Université du Québec à Rimouski

Programme :

Accelerate

Effect of Music on Interbrain Synchrony: A Close Look at Triad of Disabled Children, Parents and Music Therapist – Year two

Kids with one, two or three or more disabilities require special care and rehabilitation services. Specifically, for children with severe disabilities who are non-speaking, the opportunities for social interaction and participation are often limited. However, it is believed that these children continue to form relationships with those around them and that the brain encodes these interpersonal connections. One way to study these interpersonal brain connections is to examine the interbrain coordination between children, parents and a therapist. To this goal, we will compare the brain states of children, one of their parents and an attending therapist, in two activity settings: a music session and a story-telling session. These data are being collected at Holland Bloorview Kids Rehabilitation Hospital. This post-doctoral fellowship will focus on developing advanced machine learning and data mining algorithms to dissect these data. These data are not easily analyzed with conventional methods as they are non-stationary, multi-channel, spatially correlated within-individual, and originating from multiple individuals. The findings from this research will advance the care of children and youth with disabilities globally.

Voir la description complète du projet
Superviseur du corps professoral :

Tom Chau

Étudiant :

Partenaire :

Holland Bloorview Kids Rehabilitation Hospital Foundation;University of Toronto

Discipline :

Life Sciences

Secteur :

Finance and Insurance; Health and Related Sciences & Technology

Université :

University of Toronto

Programme :

Elevate

Développement d’une technique améliorée d’infusion de résinethermodurcissable pour la fabrication de pièces en matériaux composites à hauteperformance.

L’objectif principal du projet de recherche est de développer une nouvelle technique
économique de fabrication de pièces en matériaux composites à haute performance, pour le domaine aeronautique et operationnel chez Marquez. L’integration des nouvelles techniques
vise I’amelioration de la robustesse du procede, en minimisant les temps de cycle, les pieces
rejets et en limitant la variabilite du procetie. La nouvelle technologie qui sera developpee
dans Ie cadre de ce projet de maltrise permettra a Marquez de se demarquer en offrant des
pieces en materiaux composites a haute performance avec des cadences plus rapides et a
moindre coOt que les technologies concurrentes.

Voir la description complète du projet
Superviseur du corps professoral :

Pascal Hubert;Simon Joncas

Étudiant :

Partenaire :

Marquez

Discipline :

Physics

Secteur :

Technology; Manufacturing and Construction

Université :

École de technologie supérieure; McGill University

Programme :

Accelerate

Effect of Music on Interbrain Synchrony: A Close Look at Triad of Disabled Children, Parents and Music Therapist

Kids with one, two or three or more disabilities require special care and rehabilitation services. Specifically, for children with severe disabilities who are non-speaking, the opportunities for social interaction and participation are often limited. However, it is believed that these children continue to form relationships with those around them and that the brain encodes these interpersonal connections. One way to study these interpersonal brain connections is to examine the interbrain coordination between children, parents and a therapist. To this goal, we will compare the brain states of children, one of their parents and an attending therapist, in two activity settings: a music session and a story-telling session. These data are being collected at Holland Bloorview Kids Rehabilitation Hospital. This post-doctoral fellowship will focus on developing advanced machine learning and data mining algorithms to dissect these data. These data are not easily analyzed with conventional methods as they are non-stationary, multi-channel, spatially correlated within-individual, and originating from multiple individuals. The findings from this research will advance the care of children and youth with disabilities globally.

Voir la description complète du projet
Superviseur du corps professoral :

Tom Chau

Étudiant :

Partenaire :

Holland Bloorview Kids Rehabilitation Hospital Foundation;University of Toronto

Discipline :

Life Sciences

Secteur :

Finance and Insurance; Health and Related Sciences & Technology

Université :

University of Toronto

Programme :

Elevate

Application of advanced analytics in PEM fuel cell development and engineering

This project is a collaboration between Triptech Engineering and Software Services LTD and Laboratory for Alternative Energy Conversion (LAEC) at SFU to develop data analytics solutions for PEM fuel cell industry. The fuel cell industry is suffering from component/system failure and coping with analysis of tremendous amounts of data. Knowledge extraction from this complex data is necessary to predict key factors of component/system failure and enhance the reliability and lifetime of fuel cells. Data analytics has superior diagnostics/prognostics capabilities and is revolutionizing various fields of science and engineering by detecting unseen patterns and new knowledge hidden in massive databases of these disciplines. This project aims to exploit the power of data analytics to develop data solutions for the fuel cell industry.

Voir la description complète du projet
Superviseur du corps professoral :

Majid Bahrami

Étudiant :

Partenaire :

Triptech Engineering and Software Services LTD

Discipline :

Engineering

Secteur :

Professional, scientific and technical services

Université :

Simon Fraser University

Programme :

Accelerate

Liquid biopsy for the discovery of new methods of cancer diagnosis and new treatment strategies – Year two

Despite the improvements in cancer diagnostic and treatment, cancer is still a leading cause of death in Canada with 30% of all deaths. Some cancers, like pancreatic cancer (PC), still have poor survival rates due to the lack of early diagnosis and good prognostics markers. The Atlantic Cancer Research Institute (ACRI) has developed a proprietary technology to capture extracellular vesicles (EVs) from various biofluids with the goal to deliver precision medicine solutions through liquid biopsy technologies. Cancer cells are known to secrete EVs that carry almost every cell molecular components. This project aims to compare many components of EVs captured in plasma from cancer patients and healthy controls. The main goals of this project are to establish particular disease biosignatures and to evaluate their potential to detect and identify cancers earlier, and to evaluate the efficiency of the treatments by monitoring cancer progression. This could result in significant economic benefits for our health care systems by making sure the treatment is right for the patient and by halting expensive treatments for non-responders sooner. This represents a business opportunity if health care systems or diagnostic companies form a partnership with ACRI for the diagnosis and monitoring of cancer patients.

Voir la description complète du projet
Superviseur du corps professoral :

Marc Surette

Étudiant :

Partenaire :

Atlantic Cancer Research Institute

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

Université de Moncton

Programme :

Elevate

Liquid biopsy for the discovery of new methods of cancer diagnosis and new treatment strategies

Despite the improvements in cancer diagnostic and treatment, cancer is still a leading cause of death in Canada with 30% of all deaths. Some cancers, like pancreatic cancer (PC), still have poor survival rates due to the lack of early diagnosis and good prognostics markers. The Atlantic Cancer Research Institute (ACRI) has developed a proprietary technology to capture extracellular vesicles (EVs) from various biofluids with the goal to deliver precision medicine solutions through liquid biopsy technologies. Cancer cells are known to secrete EVs that carry almost every cell molecular components. This project aims to compare many components of EVs captured in plasma from cancer patients and healthy controls. The main goals of this project are to establish particular disease biosignatures and to evaluate their potential to detect and identify cancers earlier, and to evaluate the efficiency of the treatments by monitoring cancer progression. This could result in significant economic benefits for our health care systems by making sure the treatment is right for the patient and by halting expensive treatments for non-responders sooner. This represents a business opportunity if health care systems or diagnostic companies form a partnership with ACRI for the diagnosis and monitoring of cancer patients.

Voir la description complète du projet
Superviseur du corps professoral :

Marc Surette

Étudiant :

Partenaire :

Atlantic Cancer Research Institute

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

Université de Moncton

Programme :

Elevate

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