Nano-varnish with integrated biomineralizable and antibacterial activity against dental caries
Dental caries is a major health hazard in the general population worldwide. Fluoride-based formulations are conventionally used to resolve this problem but they present certain important disadvantages, which has been overlooked. Here we propose to develop and characterize a non-fluoride based dental varnish using natural product conjugated nanoparticles that holds the potential of inhibiting bacterial plaque formation and repair early damage on tooth surface. The potential long-term benefits of this product are extensive and include prevention of dental caries and improved quality of life. The nano-varnish is inexpensive, fast and simple to use, which can be used by dentists/individuals with minimum learning curve. The varnish fills the unmet medical need for patients with high caries risk, particularly children.
Voir la description complète du projetAnil Kishen
Germiphene Corporation
Life Sciences
Manufacturing
University of Toronto
Accelerate