Delayed drug release from electrostatic coated capsules with ultrafine powders: Preparation and evaluation

Since most capsules are made of gelatin, the aqueous coating process of capsules is very sensitive and requires a very long process time due to the aqueous solubility of gelatin substrate, resulting in high costs. Accordingly, it would be very advantageous to provide a method for dry powder coating capsules without using an organic solvent or water. The objective of the current study is to prepare and evaluate the use of electrostatic dry powder coated capsules to achieve delayed drug release. Experimentation will be carried out through the design and formulation of an electrostatic coating, the loading of a drug into the coated capsules, and the characterization of dry coated capsules and drug release in vitro. The goal of this project is to achieve delayed drug release using the dry powder coating of a pharmaceutical capsule.

Faculty Supervisor:

Jesse Zhu

Student:

Partner:

Zhejiang University of Technology

Discipline:

Life Sciences

Sector:

Education

University:

Western University

Program: