Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

31 133 projets complétés

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5159
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837
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685
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882
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9292
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9695
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97
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601
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1161
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Projets par catégorie

Targeting classically intractable molecules with Quantum Computing

With the advent of quantum computing, finding applications for which quantum computers offer an advantage with respect to classical computers is crucial if this technology is to be fruitful. One of the areas where quantum computers are expected to be particularly useful is for the simulation of molecular systems, with applications in drug discovery, materials development, and energy solutions. Even though there already exists an abundance of classical methods for this problem, for a given molecular system there exist no efficient ways of knowing whether these methods will break down or not, as it is known that some regimes cannot be solved efficiently on classical computers. As such, it is of paramount importance to develop efficient protocols that allow to test both this classical simulation complexity, and the quantum simulation complexity, of a given molecular system. Our research will focus on developing these protocols, which will allow for the evaluation of technologically relevant systems and the determination of whether their simulation can be done in a classical computer, or if a quantum computer is necessary.

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Superviseur du corps professoral :

Artur Izmaylov

Étudiant :

Partenaire :

Zapata Canada

Discipline :

Physics

Secteur :

Professional, scientific and technical services

Université :

University of Toronto

Programme :

Elevate

The Canadian Donor Milk Trial (CanDo): Pasteurized human donor milk supplementation in the well baby unit

The proposed trial will evaluate the benefit of using donor human milk versus formula as a supplement to parent milk, when the latter is unavailable, in the well-baby nursery. Although the goal for infant feeding is exclusive parent milk from birth, up to 50% of all infants in well-baby units receive a supplement for a variety of reasons including parent illness, infant low blood sugar or excessive weight loss, and in the instance of two-father families among other reasons. The current standard is for this supplement to be infant formula, however the practice of using human donor milk for this population is growing without any research-based evidence. In view of limited human donor milk in Canada, its use is prioritized to sick, hospitalized infants where there is research evidence for its benefit. It is an opportune time to determine if providing human donor milk to well newborns in well-baby units is scientifically merited. The primary outcome will be exclusive human milk feeding at 4 months as it is hypothesized that provision of donor milk will improve the duration and exclusivity of human milk feeding and the latter is associated with a multitude of health and development advantages.

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Superviseur du corps professoral :

Sharon Unger;Deborah O'Connor

Étudiant :

Partenaire :

Sinai Health System

Discipline :

Life Sciences

Secteur :

Health and Related Sciences & Technology; Manufacturing

Université :

University of Toronto

Programme :

Elevate

Developing chemical probes for inhibition and targeted degradation of the deubiquitinase USP9X in breast cancer

Cells have developed an intricate system called ubiquitination to control the quantity of certain proteins. As this is frequently hijacked in various cancers, the Structural Genomics Consortium (SGC) intends to inhibit components of ubiquitination with small molecules for therapeutic benefit. Partnership of the SGC with the cell biology expertise of Barsyte-Lovejoy group will allow for cellular investigation of new and specific compounds that can manipulate the ubiquitination machinery as an anticancer therapy. USP9X is a protein component of the ubiquitination machinery that promotes breast cancer development. In this proposed project, the student will focus on the ability of SGC-developed compounds to selectivity target USP9X in cells and assess if these compounds impair breast cancer tumourigenesis. This will lead to better understanding of USP9X biology and the possible development of a new therapeutic that expands SGC’s portfolio and efforts in probing the components of ubiquitination.

Voir la description complète du projet
Superviseur du corps professoral :

Dalia Barsyte-Lovejoy

Étudiant :

Partenaire :

Structural Genomics Consortium

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Toronto

Programme :

Elevate

Assessing Community Well-being Risk for Supporting Decisions on Investments for Social Sustainability

Community well-being is important for building housing, income, food, and health security. The COMEAI causal model is available for evaluating the risk to housing, income, food, and health security criteria. The model has a potential for improvement to account for the lack of critical practical application and evidence-based literature support. This research aims to validate the indicators of well-being criteria and improve the existing risk assessment model for evaluating projects to assist risk informed decision-making. The existing COMEAI model will be improved to incorporate uncertainty using the available literature and expert opinions on the types of indicators, and weights of criteria and indicators. The evaluated community well-being risk score will be compared with the risk level estimated using the existing model. Based on this, an improved risk assessment model will be proposed.

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Superviseur du corps professoral :

Rehan Sadiq;Kasun Hewage

Étudiant :

Partenaire :

PRISM Institute

Discipline :

Engineering

Secteur :

Professional, scientific and technical services

Université :

The University of British Columbia - Okanagan

Programme :

Accelerate

Development and manufacturing of functionalized oxime crosslinked hyaluronan hydrogel for sustained drug release to treat retinal degeneration

Retinal degeneration disorders are among the leading causes of blindness in the developed world. Several therapies hold promise, however widespread application is hindered due to difficulty in delivering active drug to the retina. Synakis is a company that has developed a biomaterial that can be injected into the eye to aid in retinal surgeries. This material serves as an ideal vehicle to deliver highly potent therapies to the retinal to treat retinal degeneration. This project aims to engineer Synakis’ material to deliver therapies directly to the retina. If successful, this technology will open up extensive commercial opportunities for Synakis as a platform technology to delivery critically needed regenerative therapeutics to the eye.

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Superviseur du corps professoral :

Molly Shoichet

Étudiant :

Partenaire :

Synakis

Discipline :

Life Sciences

Secteur :

Manufacturing; Professional, scientific and technical services

Université :

University of Toronto

Programme :

Elevate

Le contrôle moteur étudié chez le rongeur par une analyse cinématique 3D

Nous étudions les mécanismes de la récuperation motrice chez le rongeur, où nous développons des systèmes intégrés d’intervention par neuromodulation du cerveau et de la moelle épinière. M. Ferotin mettra en œuvre un pipeline d’analyse cinématique 3D basé sur trois caméras positionnées autour d’une plate-forme comportementale, où le contrôle du mouvement des membres antérieurs du rat est évalué. La tâche de collecte de granules de nourriture à travers une fenêtre à fente nous permet de disséquer les composantes les plus fines du contrôle moteur des membres antérieurs.

Voir la description complète du projet
Superviseur du corps professoral :

Marco Bonizzato

Étudiant :

Partenaire :

École Centrale de Lyon

Discipline :

Life Sciences

Secteur :

Education

Université :

Université de Montréal

Programme :

Globalink Research Award

Étude comparative de modèles de segmentation d’instances de légumes

Pour résoudre une problématique liée à l’analyse d’images en temps réel, Lapalme Gestion Conception Mécanique recherche un algorithme d’intelligence artificielle qui soit performant dans un contexte de tâches agricoles. Cependant, malgré la grande quantité de recherche faite en intelligence artificielle, l’évaluation de modèles sur des données agricoles est plutôt rare. Ce projet vise donc à effectuer une étude comparative de l’efficacité de modèles de segmentation d’instances sur les images de légumes de Lapalme Gestion Conception Mécanique. Cette recherche contribuera à augmenter les connaissances dans le domaine de l’apprentissage profond en fournissant un comparatif quant à l’applicabilité de modèles de segmentation d’instances à des données agricoles.

Voir la description complète du projet
Superviseur du corps professoral :

Brahim Chaib-draa

Étudiant :

Partenaire :

Lapalme Gestion Conception Mécanique

Discipline :

Computer science

Secteur :

Professional, scientific and technical services

Université :

Université Laval

Programme :

Accelerate

Combining net ecosystem CO2 exchange and soil CO2 efflux measurements to partition ecosystem respiration in a mixed wood forest

Most forests slow down climate warming by removing CO2 from the atmosphere and storing it in biomass and soils. However, how much CO2 they remove depends on how much CO2 different forest compartments (vegetation and soils) take up from or release to the atmosphere. New sensor technologies have been developed allowing year-round measurements of CO2 release from soils and overall forest-atmosphere CO2 exchange. We will use state-of-the-art soil CO2 flux sensors to measure how much CO2 release from soils in an Acadian forest ecosystem contribute to the overall CO2 exchange. We will track how the contributions from individual forest compartments change over the course of autumn and early winter in response to falling leaves and beginning of the snow cover period. Benefits to the partner organisation Eosense Inc. include the collection of testing and measurement data from the innovative soil sensors for further Research and Development and photos and information material for marketing and sales purposes.

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Superviseur du corps professoral :

Manuel Helbig

Étudiant :

Partenaire :

Eosense

Discipline :

Earth science

Secteur :

Manufacturing; Professional, scientific and technical services

Université :

Dalhousie University

Programme :

Accelerate

Research and Development of Ultra-portable Modulus Structures

Canada is considered to be one of the leading nations in nature conservation. Greenheart specializes in the design and construction of aerial trails. University of British Columbia (UBC) is a world renowned institute for structural engineering research. This Mitacs Intern Program is intended to create a robust research program that allows UBC researchers to collaborate with Greenheart to design ultra-portable, reconfigurable and lightweight structures which can be used for education, enjoyment, promotion and preservation of our environment. The program will consist of extensive array of analytical simulations, experimental testing and design optimizations. Upon successful implementation of the research, the program will train multiple highly qualified personnel with vital scientific and business skills that will further strengthen Canada’s position in pioneering engineering research and continue Canada’s leadership in nature conservation.

Voir la description complète du projet
Superviseur du corps professoral :

Tony Yang

Étudiant :

Partenaire :

Greenheart Canopy Walkway Company Ltd

Discipline :

Engineering

Secteur :

Professional, scientific and technical services

Université :

The University of British Columbia

Programme :

Accelerate

Secwe´pemc-led monitoring and restoration in fire-adapted landscapes: revitalizing roles as yecwmi´nmen

This project is in partnership with the Secwepemcúl’ecw Restoration and Stewardship Society, founded by eight Secwépemc First Nations to advance Secwépemc-led restoration and sustainable stewardship of lands and resources throughout Secwepecúl’ecw (the traditional territory of the Secwépemc Nation). Guided by the Secwépemc concept of ‘walking on two legs’, our project advances a novel pathway of Indigenous-led monitoring and restoration in BC’s fire-affected and fire-adapted landscapes. Through interdisciplinary and Indigenous-led research we will work with Secwépemc Elders, heritage keepers and natural resource and cultural heritage staff to achieve three interconnected objectives. Specifically, we will document the effects of wildfire and post-fire forest recovery activities on traditional foods and medicines; develop a culturally relevant framework, including protocols, for monitoring cultural heritage resources and to promote Secwépemc participation in forest stewardship; and revitalize Secwépemc knowledge and practices of fire and plant stewardship in order to inform alternative forest management and restoration strategies. By walking on two legs, our project will also respectfully draw on both Secwépemc knowledges and western sciences in service of elevating Secwépemc stewardship goals and supporting Secwépemc communities (re)assert jurisdiction over cultural heritage management throughout their territories.

Voir la description complète du projet
Superviseur du corps professoral :

Lori Daniels

Étudiant :

Partenaire :

Secwepemcúl'ecw Restoration and Stewardship Society

Discipline :

Sociology

Secteur :

Sustainability & the Environment; Social Innovation; Agriculture and Food

Université :

The University of British Columbia

Programme :

Elevate

Aluminum and water process for sustainable cogeneration hydrogen, high-purity alumina and heat

There is an urgent need for carbon free sources of energy to mitigate the climate change effects. Hydrogen is a very promising fuel to transition to climate-friendly energy and sustainable energy future. However, most hydrogen is produced from carbon sources and thus undesired emissions are unavoidable during the production. One key solution is to use extract hydrogen by reacting metal powders with water. In this research, aluminum and iron powders are used to cogenerate hydrogen and high-purity alumina in a carbon neutral process. This process contributes to the goal for a net-zero emission economy in Canada by 2050.

Voir la description complète du projet
Superviseur du corps professoral :

Reza Kholghy

Étudiant :

Partenaire :

GH Power

Discipline :

Engineering

Secteur :

Clean Technology; Green/Alternative Energy; Technology

Université :

Carleton University

Programme :

Elevate

The effects of COVID-19 mediated reduction of human recreation on the movement ecology of southern mountain caribou.

Southern mountain caribou inhabit high elevation forests and parkland in late winter when snow depth facilitates access to arboreal lichens, their preferred winter food source. Use of these habitats coincides with human recreational use of these same areas by helicopter skiing, commercial backcountry skiing and snowmobiling (backcountry recreation).
The COVID-19 related travel restrictions implemented in 2021 resulted in the cessation (heli-skiing) or severe reduction in human recreational use of these environments. Our research will examine whether home range size, movement metrics and habitat use differed between years when backcountry recreation was occurring normally (2019 and 2020), the ‘anthropause’ period (2021) and the period after the COVID-19 related travel restrictions were lifted (2022).
Understanding the effects of human disturbance on this species will inform management decisions around recreational tenure management in BC.

Voir la description complète du projet
Superviseur du corps professoral :

Michael Noonan

Étudiant :

Partenaire :

Alberta Biodiversity Monitoring Institute

Discipline :

Earth science

Secteur :

Professional, scientific and technical services

Université :

The University of British Columbia - Okanagan

Programme :

Accelerate

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Mitacs — Retour sur innovation

Mitacs est financé par le gouvernement du Canada, le gouvernement de l’Alberta, le gouvernement de la Colombie-Britannique, Research Manitoba, le gouvernement du Nouveau-Brunswick, le gouvernement de la Nouvelle-Écosse, le gouvernement de l’Ontario, Innovation PEI, le gouvernement du Québec, le gouvernement de la Saskatchewan, le gouvernement de Terre-Neuve-et-Labrador et le gouvernement du Yukon.