Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

30 508 projets complétés

2882
AB
5105
C.-B.
825
MB
681
NL
860
SK
9051
ON
9491
QC
97
PE
586
NB
1141
NS

Projets par catégorie

Development of a novel robust clone for the manufacturing of AVID100 biosimilar

AVID100 is an antibody-drug conjugate (ADC) against a validated cancer target that is undergoing IND-enabling studies. Phase I clinical trials are scheduled for late 2016. The monoclonal antibody (mAb) portion of the ADC is currently manufactured using a recombinant CHO clone that fails to meet industrial production yield standards. In order to support clinical phases II and III as well as commercial supply a higher-expressing cell line must be developed. MAb product characteristics will need to be similar to the current clone, namely with regards to the N-glycan composition. We will thus develop an accelerated clone selection process using a fluorescence activated cell sorter combined with a high-resolution imaging system for monoclonality demonstration. A micro-bioreactor system will be used to rapidly compare multiple clones to select for stability, productivity and N-glycan profile. Manufacturing cost reductions and improved clinical supply risk mitigation are the partner’s intended benefits.

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Superviseur du corps professoral :

Yves Durocher

Étudiant :

Partenaire :

Formation Biologics Inc

Discipline :

Life Sciences

Secteur :

Manufacturing

Université :

Université de Montréal

Programme :

Elevate

Radio Acoustical Virtual Environment: from Lab to Field – Year 2

In a world that is getting noisier and as more people are at risk of noise-induced hearing loss the NSERC-EERS industrial research chair in in-ear technologies (CRITIAS) and its industrial partner EERS, have joined forces to address the existing issues in hearing protection devices (HPD). Difficulties in communication is the most prevalent reason why HPDs are not worn in noisy environments. The goal of this project is to enhance communication for talkers wearing HPDs in noise. This is done by capturing speech from inside the occluded ear, denoising it and extending its frequency bandwidth. Once enhanced, the speech signal is sent to listeners within a spatial range of a talker. This range is determined by monitoring the vocal effort of the talker and the level of background noise. Such a Radio Acoustical Virtual Environment enhances the quality of communication in noise and encourages the continuous use of HPDs in noise.

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Superviseur du corps professoral :

Jérémie Voix

Étudiant :

Partenaire :

EERS Global Technologies Inc

Discipline :

Engineering

Secteur :

Information and Communications Technology; Health and Related Sciences & Technology; Technology

Université :

École de technologie supérieure

Programme :

Elevate

Radio Acoustical Virtual Environment: from Lab to Field

Verbal communication in noise while wearing hearing protection devices (HPDs) is often difficult. Recently, a “Radio Acoustical Environment” (RAVE) was developed within the EERS-ETS Industrial Research Chair in In-Ear Technologies (CRITIAS) to enhance communication for people wearing HPDs in noise. With RAVE, speech is captured from inside the ear, denoised, and enhanced to be sent only to listeners within a given spatial range. This range is determined based on the changes in the talker’s vocal effort and background noise level. Currently, RAVE is at its prototype stage. During this Postdoctoral Fellowship, the algorithms developed for RAVE will be implemented on DSP and optimized. Subjective intelligibility tests will be performed to benchmark the speech-based algorithms. Finally, realistic features will be added to transmitted signals to enhance processes such as localization and distance perception. This project in partnership with EERS will enable the completion of a very unique and innovative commercial project.

Voir la description complète du projet
Superviseur du corps professoral :

Jérémie Voix

Étudiant :

Partenaire :

EERS Global Technologies Inc

Discipline :

Engineering

Secteur :

Information and Communications Technology; Health and Related Sciences & Technology; Technology

Université :

École de technologie supérieure

Programme :

Elevate

Going beyond genomics: Applying gene editing to the bovine industry – Year 2

A new revolution in life science research is ongoing since the discovery of the CRISPR/Cas system. With this technology is now possible to specifically and efficiently manipulate the genome of cultured cells, embryos and animals. The technology has many applications in agriculture including the dairy genetic industry to generate the next generation of elite animals having improved traits. For example, using the CRISPR/Cas technology it is now possible to produce dairy cows of any bloodline having improved traits for health, welfare, production and management. L’Alliance Boviteq Inc. is a world leading company in the field of bovine genetics and reproductive biotechnology, and possesses the best in vitro technologies for bovine embryo production. Introduction of gene editing technologies will help L’Alliance Boviteq Inc. creating the best animals for the Canadian dairy industry.

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Superviseur du corps professoral :

Vilceu Bordignon

Étudiant :

Partenaire :

L'Alliance Boviteq Inc

Discipline :

Life Sciences

Secteur :

Agriculture; Professional, scientific and technical services

Université :

McGill University

Programme :

Elevate

Going beyond genomics: Applying gene editing to the bovine industry

A new revolution in life science research is ongoing since the discovery of the CRISPR/Cas system. With this technology is now possible to specifically and efficiently manipulate the genome of cultured cells, embryos and animals. The technology has many applications in agriculture including the dairy genetic industry to generate the next generation of elite animals having improved traits. For example, using the CRISPR/Cas technology it is now possible to produce dairy cows of any bloodline having improved traits for health, welfare, production and management. L’Alliance Boviteq Inc. is a world leading company in the field of bovine genetics and reproductive biotechnology, and possesses the best in vitro technologies for bovine embryo production. Introduction of gene editing technologies will help L’Alliance Boviteq Inc. creating the best animals for the Canadian dairy industry.

Voir la description complète du projet
Superviseur du corps professoral :

Vilceu Bordignon

Étudiant :

Partenaire :

L'Alliance Boviteq Inc

Discipline :

Life Sciences

Secteur :

Agriculture; Professional, scientific and technical services

Université :

McGill University

Programme :

Elevate

A business case study of the automotive cluster around the city of Ahmedabad

In 2010, Tata’s first Nano rolled off the assembly line near Ahmedabad, India; the plant was the first automotive manufacturing facility in the area. However, within just a few years, Ford, GM
and Suzuki had opened new plants close by, and the region now produces a million cars annually.
It is accepted that businesses or commercial units agglomerate around a certain area – commonly known as clustering. In this way, the firm can take advantage of numerous spillover
effects from its surroundings including lower transportation costs, a larger labor market, and heightened competition.
The object of this research for Harvard Business School’s Institute of Strategy and Competitiveness is to undertake a comprehensive case study on the intricacies of Ahmedabad’s automotive cluster. This will consist of a background on the competitive position of both India and Gujarat, an analysis of the cluster and its challenges, along with a series of
recommendations on how both public and private stakeholders can further improve the cluster’s productivity.

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Superviseur du corps professoral :

Thomas Ross;Frances Chandler

Étudiant :

Partenaire :

Indian Institute of Management Ahmedabad

Discipline :

Business

Secteur :

Agriculture

Université :

The University of British Columbia

Programme :

Globalink Research Award

Comparative analysis of merger control mechanisms in Canadian and Mexican competition law

This research project conducts a comparative analysis of the provisions of Canadian and Mexican competition laws that deal with the control of mergers and acquisitions. Usually, merger control mechanisms require that a proposed transaction whose value exceeds a certain threshold be notified to the competition authorities of the country where the transaction is to take place. Cross-border mergers and acquisitions between Canadian and Mexican firms may have to be notified to both the Canadian Competition Bureau and the Mexican Federal Economic
Competition Commission. A comparative overview of the requirements and assessment framework imposed by the competition legislation of both countries in terms of mergers is
valuable for the business community, lawyers and competition authorities. Business decisionmakers will be able to better strategize about cross-border expansion, lawyers will be more
adept at advising clients who intend to engage in merger and acquisitions activities abroad and competition authorities will be better equipped to coordinate their assessment of mergers
notified in both countries

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Superviseur du corps professoral :

Thomas Ross

Étudiant :

Partenaire :

Universidad Nacional Autónoma de México

Discipline :

Sociology

Secteur :

Education

Université :

The University of British Columbia

Programme :

Globalink Research Award

Surface Rights in the Dasiqox Tribal Park

Just months the June 2014 the Supreme Court of Canada decision granting partial title to the Tsilhqot’in First Nation’s land claim, the communities of Xeni Gwet’in and Yunesit’in, with support form the Tsilhqot’in National Government, declared another traditional area, just beyond the granted claim, as the Dasiqox Tribal Park. The surface area of the new park contains a barrier to Tsilhqot’in self-governance in the form of an undetermined amount of mineral claims staked under the mineral tenure system of British Columbia. In cooperation with (and as a contribution to) the work of Fair Mining Collaborative, this post-doctoral project will achieve three things: 1) examine the evolution of mineral tenure in a new social and legal environment, including through the creation of an inventory of mineral tenure in the Dasiqox Tribal Park; 2) contribute to the design and implementation of a governance framework for the new park, in light of these changes, using Tsilhqot’in traditional values; 3) contribute to FMC’s work drafting recommendations for new mineral tenure law in BC.

Voir la description complète du projet
Superviseur du corps professoral :

Terre Satterfield

Étudiant :

Partenaire :

Fair Mining Collaborative

Discipline :

Sociology

Secteur :

Education

Université :

The University of British Columbia

Programme :

Accelerate

Power transducer improvement for Etalim TAC heat engine

Etalim is a Canadian high technology company developing a breakthrough heat engine generating electricity from any fuel or heat source. The Etalim TAC (Thermal Acoustic Converter) is a unique technology that converts any high temperature gradient to electricity, with high efficiency (20%-30%) and simplicity. The TAC represents a unique class of device that combines principles of thermodynamics, high-amplitude acoustics, mechanical resonance and materials science in a unique way. Etalim is in joint development with top global automotive and HVAC brands to commercialize the TAC technology in billion-dollar markets for exhaust waste heat recovery on trucks, and for distributed residential co-generation. The proposed project involves improvements in the power transducer system of the TAC, and makes the company one step closer to commercializing the TAC technology.

Voir la description complète du projet
Superviseur du corps professoral :

Farid Golnaraghi

Étudiant :

Partenaire :

Etalim Inc

Discipline :

Engineering

Secteur :

Professional, scientific and technical services

Université :

Simon Fraser University

Programme :

Accelerate

Optimisation de la qualité des images etvisualisation des tissus mous : mise au point denouvelles approches en CBCT

L’imagerie cone beam CT (CBCT) prend une place de plus en plus importante dans l’exploration des structures osseuses du complexe dento-maxillo-facial. Cette modalité d’imagerie, moins irradiante que l’imagerie par tomodensitométrie conventionnelle (TDM), procure des images de qualité similaire, voire supérieure, à celle des images TDM. Toutefois, les rapports Signal/Bruit ne sont pas assez élevés, et les doses, bien qu’inférieures à celles en TDM, pourraient encore être diminuées. Un des objectifs de ce projet est donc d’optimiser la qualité des images tout en cherchant à réduire davantage la dose de radiation ionisante. Pour atteindre ce double objectif, nous proposons de mettre en oeuvre de nouveaux algorithmes de reconstruction/rétroprojection, notamment en faisant appel à des méthodes de reconstruction itératives. Le rehaussement qualitatif obtenu, associé à de nouvelles modalités d’acquisition en double énergie, devrait nous permettre d’accéder, pour la première fois en imagerie CBCT, à une visualisation nettement améliorée des tissus mous, laissant entrevoir ainsi de très larges perspectives pour cette modalité d’imagerie très prometteuse.

Voir la description complète du projet
Superviseur du corps professoral :

Jacques de Guise

Étudiant :

Partenaire :

Useful Progress Service Inc

Discipline :

Engineering

Secteur :

Health and Related Sciences & Technology; Information and Communications Technology; Technology

Université :

École de technologie supérieure

Programme :

Accelerate

A Generalized Model Predictive Path Planning System for Autonomous Vehicles on Structured Roads

Autonomous vehicles process the data received from their sensors to recognize the road and the obstacles in their perception module, and determine the desired route via the decision making module. Then, in the path planning module, they plan a path so that the vehicle follows the route while it observes the rules, avoids obstacles, and keeps the vehicle stable. Two common path planning methods, potential fields and model predictive controllers, have been combined in this project to develop a path planning module that is general, optimal, and predictive. The developed module has been simulated and showed an appropriate performance. In this project, the module is implemented on the autonomous vehicle of the host lab to validate the simulations. The path planning module is modified to be compatible with other modules used in the autonomous vehicle (the perception and decision making modules). It is also tuned for the vehicle, so that the experimental planned paths are as good as the simulation results.

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Superviseur du corps professoral :

Amir Khajepour

Étudiant :

Partenaire :

Beijing Institute of Technology

Discipline :

Engineering

Secteur :

Education

Université :

University of Waterloo

Programme :

Globalink Research Award

Human Thermoregulation and Technical Apparel

Nature of the work: This project will assess a novel lululemon clothing ensembles during transitions between differing environments.
Anticipated Outcomes: An optimization of the design of clothing ensembles for transitions between different environments is the anticipated outcome.
Relevance: The project will provide garments for Canadians to improve their health, safety and comfort during outdoor activities. lululemon employs over 2700 people and the project will help start training new experts and to develop the best possible garments for active Canadians.
Benefits to Canada: Economic benefits to Canada include building of expertise in highly qualified personnel in the rapidly expanding technical apparel industry sector. Environmental benefits include that garments developed by lululemon are for human powered pursuits including bicycle commuting, walking, hiking etc that help reduce green-house gas emissions and global warming. Social benefits include providing improved garments to allow Canadians to stay active in aerobic activities in differing climates. Aerobic activities reduce risk of heart disease, Type II diabetes and stroke which are among the three leading causes of mortality in Canada.

Voir la description complète du projet
Superviseur du corps professoral :

Matthew White

Étudiant :

Partenaire :

Lululemon

Discipline :

Life Sciences

Secteur :

Health and Related Sciences & Technology; Environmental Science and Technology; Technology

Université :

Simon Fraser University

Programme :

Accelerate

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