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Projets par catégorie

Stability of Protein-PEDOT:PSS Coating for Implantable Electrodes

Medical devices that are implanted into the human body allow for continuous medical monitoring and intervention, such as stimulation, recording, and drug delivery. Cardiac pacemakers and insulin pumps are examples of novel technology implanted for long-term treatment. For the treatment of neurological disorders, recent advances in neuroengineering consider the use of implantable electrodes. However, these electrodes have yet to be safely implanted for extended periods and provide efficient electrical impulses (stimulation) to brain tissue. Scientists, engineers and clinicians from the University of Cambridge and McGill will cooperate to create a protein-based coating for electrodes and track the aging of the electrodes in environments like that of the human brain. The use of proteins, whose properties allow for the creation of soft and resistant materials, is thought to be a newfound solution to the long-standing problem of device stability and longevity. This project will open up new avenues for fabricating better biomedical devices and eventually contribute to safely treating diseases like Parkinson’s and Crohn’s disease, suppressing epileptic seizures, and more.

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Superviseur du corps professoral :

Noemie-Manuelle Dorval Courchesne

Étudiant :

Partenaire :

Université de Cambridge

Discipline :

Génie

Secteur :

Éducation

Université :

Université McGill

Programme :

Bourse de recherche Globalink

Combining Online and Face-to-Face Learning to Optimize Overall Learning

The project is intended to support and enhance the learnings provided by Stem Minds – a Toronto based start-up that provides digital learning focused on Science, Technology, Engineering and Mathematics (STEM), through the approach of gamification. The project will focus on the factors that motivate students to learn STEM subjects through gamification to deepen their learning experience and thus enhancing student engagement.
The goal of this study is to provide Stem Minds with an evidence-based approach to using the most powerful gamification factors in the optimal ways. The study will also consider the psychological theory explaining why and how these factors have their impact. By combining these two, Stem Minds will have a guiding document that they can use as they implement existing forms of gamification into their system, and as they potentially come up with new and innovative approaches informed by psychological theory.

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Superviseur du corps professoral :

Steve Joordens

Étudiant :

Partenaire :

Esprits Souches

Discipline :

Sciences de la vie

Secteur :

Éducation

Université :

Université de Toronto

Programme :

Accélération

Understanding juvenile salmon passage at newly created breaches in two major barriers in the Fraser River estuary, BC.

Estuaries are crucial stopover areas for juvenile salmon during outmigration and especially for Chinook salmon who can reside in this habitat for over a month. Many populations of Chinook salmon from the Pacific Northwest are threatened and endangered making conservation important for this species. Currently, managers are investing significant public funds in estuary restoration and understanding the effectiveness of these investments is crucial to recovery of many salmon populations. This research will provide a greater understanding of the benefit of two large projects to restore connectivity in the Fraser estuary, BC, and area highly impacted by anthropogenic barriers. This research will monitor juvenile salmon use of newly created breaches in two large jetties including measuring rates of passage at breach sites as well as investigating local changes in juvenile salmon habitat use. This information will help government managers and NGO’s in there future efforts to restore salmon populations in this region.

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Superviseur du corps professoral :

Scott Hinch

Étudiant :

Partenaire :

Canards Illimités Canada (C.-B.)

Discipline :

Sciences de la vie

Secteur :

Finance et assurance; Autres services (sauf l’administration publique); Services professionnels, scientifiques et techniques

Université :

L’Université de la Colombie-Britannique

Programme :

Accélération

Identification of early markers of developmental epigenetic anomalies in bovine production

Bovine production uses a combination of Assisted Reproductive Techniques (ARTs) to improve yield and reduce generation time. In bovine production and in clinical settings, ARTs are associated with elevated rates of developmental disorders in offspring, leading to animal distress, high costs and delayed results. These include Large Offspring Syndrome (LOS) and musculoskeletal anomalies, reported to have a higher prevalence in ART, and are thought to be in part the result of defects in genomic imprinting or other epigenetic disorders. At Boviteq, in vitro produced (IVP) blastocysts undergo a series of morphological and genetic screens to select for embryos with the highest potential. Despite these precautions, < 2% of calves are born with perinatal anomalies. Here, we propose to use a combination of high throughput sequencing approaches in normal and abnormal perinatal samples and in blastocysts to identify epigenetic loci that could be indicative of adverse outcomes. In addition, we will use combined transcriptomic and epigenomic approaches in single blastocysts to generate a transcriptional signature associated with normal or abnormal epigenetic marking at these loci. Through the identification of proxy markers associated with a suboptimal epigenome in the blastocyst, we hope to improve the selection of high-quality IVP embryos

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Superviseur du corps professoral :

Julie Brind’Amour

Étudiant :

Partenaire :

L’Alliance Boviteq Inc

Discipline :

Sciences de la vie

Secteur :

Agriculture; Services professionnels, scientifiques et techniques

Université :

Université de Montréal

Programme :

Accélération

Improving the performance of manufacturing processes at GE Bromont by using artificial intelligence and pattern recognition

The products manufactured at GE Bromont go through a series of processes that produce the specific characteristics of each product according to required specifications. The number of these characteristics is very large, and several characteristics are dependent on the others. This reality makes the use of traditional statistical techniques for quality control of products laborious and possibly ineffective.
The objective of this research is to improve the performance of manufacturing processes at GE Bromont to increase the number of final products that meet specifications without having to go through non-value-added steps, and to reduce the number of products’ rejects or rework.

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Superviseur du corps professoral :

Soumaya Yacout

Étudiant :

Partenaire :

GEC Aviation inc

Discipline :

Génie

Secteur :

Manufacturing and Construction; Artificial Intelligence; Advanced Manufacturing

Université :

Polytechnique Montréal

Programme :

Accélération

Improving performance of recycled asphalt applications with bitumen and asphaltenes mix

New innovative technology is proposed for Recycled Asphalt Shingles (RAS) to produce cold mix asphalt (CMA) for dust control in unpaved roads. This novel method will design a mix of bitumen/RAS/water emulsions that break in a controlled manner upon field application. The effect of asphaltenes, petroleum solvents, emulsifier type, concentration and properties, and the preparation conditions, such as agitation speed, temperature, and the order in which components are added on the performance of the emulsions will be evaluated. Considering the large amount of asphalt shingles and residual feedstock in Canada, the success of this project helps Synchor Recycling Inc.
to commercialize this technology and sell a high price RAS-based cold mix which will increase their revenue that can later be leveraged to further advance this project. Further, the project turns solid waste, like asphalt shingles, into value added product, thus making the RAS process sustainable and environmentally friendly.

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Superviseur du corps professoral :

Nashaat Nassar

Étudiant :

Partenaire :

Synchor Recycling Inc.

Discipline :

Génie

Secteur :

Services administratifs et de soutien, gestion des déchets et remédiation

Université :

Université de Calgary

Programme :

Accélération

Using high-throughput mapping techniques to reveal mechanisms of vocal learning

Understanding how humans and non-human animals communicate with each other continues to be a central question in neuroscience. Songbirds serve as powerful animal models for this endeavor because they learn their vocalizations (“songs”) in a manner that resembles how humans learn to speak and because vocal learning in songbirds is regulated by discrete brain circuits that are analogous to brain areas implicated in speech acquisition in humans. We propose to take advantage of a novel, high-throughput, and barcode-based sequencing technique called MAPseq (Multiplexed Analysis of Projections by Sequencing) to simultaneously map the projections of thousands of individual neurons in the songbird brain. Our analyses will target a brain region (“RA”) that plays a central role in vocal learning and performance in songbirds. The direct projection from RA to a hindbrain area for vocal control (“nXIIts”) is observed only in bird species that evolved the ability to learn their vocalizations and, thus, implicated in the evolution of vocal learning. [Comparative studies in mammals also underscore the importance of a direct cortical-hindbrain projection for vocal learning.]

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Superviseur du corps professoral :

Jon Sakata

Étudiant :

Partenaire :

Université Johns Hopkins

Discipline :

Sciences de la vie

Secteur :

Life Sciences (not health); Biotechnology

Université :

Université McGill

Programme :

Bourse de recherche Globalink

Development of an Integral Strategy for Model-based Dose Adaptation in Chemotherapy Year Two

Drug models describe the relationship between exposure (or pharmacokinetics), response (or pharmacodynamics) for both desired and undesired effects, and individual patient characteristics. In this project, drug models will be used to propose an integrated dose adaption strategy for cancer treatment. This strategy has a particular clinical value for our partner (InVentiv Health Clinical, a Contract Research Organization) because it would allow to better inform of the drug development process, thus reducing studies´ cost, drug development duration and risks in a long run. Furthermore, there is a potential benefit for cancer patients. An adequate dose adaption strategy would theoretically decrease its associated toxicities and therefore, the “quality of life” of the cancer patient might be deeply improved

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Superviseur du corps professoral :

Fahima Nekka

Étudiant :

Partenaire :

inVentiv Health

Discipline :

Sciences de la vie

Secteur :

Fabrication

Université :

Université de Montréal

Programme :

Elevate

Syncrétisme royal et divin dans la numismatique d’Argilos

Bien que les monnaies aient été largement remplacées ces dernières années par des systèmes informatiques sous forme de crédit, l’importance et la valeur d’une unité de transaction restent des éléments de très grande importance, et ce, autant pour nous aujourd’hui que pour les Grecs de l’Antiquité. Les unités de transaction en elles-mêmes datent de plusieurs milliers d’années, et varient dans leurs formes, mais l’utilisation de monnaies en métal, elle, se situe dans le contexte particulier du monde grec archaïque du 7e siècle avant notre ère. Pour ce qui est de mon projet de recherche en lui-même, la problématique s’intéressera à toutes les monnaies découvertes sur le site d’Argilos, puisque l’objectif sera de déterminer les changements distinctifs des représentations royales dans l’ensemble de la période d’occupation d’Argilos, c’est-à-dire entre le 7e siècle et le 4e siècle. Cela peut inclure le style de représentation physique par portrait du dirigeant tout autant que les éléments symboliques pouvant signifier quelconques affiliations du souverain avec une ou des divinité(s).

Voir la description complète du projet
Superviseur du corps professoral :

Jacques Perreault

Étudiant :

Partenaire :

Université de Patras

Discipline :

Sociologie

Secteur :

Tourism; Commercial Services; Education

Université :

Université de Montréal

Programme :

Bourse de recherche Globalink

Dealing with the “forever” chemicals: To develop a compact system for the treatment of aqueous film forming foams (AFFF) flush water

The decades of uncontained use of aqueous film forming foams (AFFF) is believed to be one of the main reasons of soil and groundwater per- and poly-fluoroalkyl substances (PFAS) contamination. PFAS are widely considered to be “forever chemicals” because of their extreme inertness in the environment and even water and wastewater treatment systems. Recognizing the serous environmental and health impacts of PFAS, it is no doubt that existing PFAS-impacted sites should be remediated, and PFAS-containing waste streams should be adequately treated before discharging. The partner (a local airport) is going to upgrade their fire-fighting system with a novel AFFF product that is more environmentally responsible. Thus, a thorough flushing of the system is needed before the new AFFF is introduced into the system. The resultant AFFF flush water will then need to be properly treated, and the RAA is therefore seeking a cost-effective technology for this purpose. This Mitacs Accelerate project will develop and test multiple treatment technologies for AFFF flush water. Techno-economic analyses will help the partner decide the most cost-effective treatment solution for the AFFF flush water issue as well as formulate its long-term strategic plan for future remediation of its AFFF-impacted sites. The technology and findings will

Voir la description complète du projet
Superviseur du corps professoral :

Jinkai Xue

Étudiant :

Partenaire :

Regina Airport Authority Inc.

Discipline :

Génie

Secteur :

Transport et entreposage

Université :

Université de Regina

Programme :

Accélération

To promote the environmental stewardship of the aviation industry in the Canadian Prairies: The development of a mobile treatment system for aircraft de-icing fluid waste

The Canadian aviation industry is anxious to recovery from the impact of COVID-19 pandemic. More air traveling requires more extensive application of aircraft de-icing fluid (ADF) to ensure aviation safety in freezing seasons. The major ingredients of ADF include anti-freeze agent (ethylene or propylene glycol), corrosive inhibitors, surfactants, pH buffers, polymers, and dyes. These chemicals are environmentally harmful. For example, glycols are detrimental to aquatic life. According to literature, 80% of the applied ADF flows off the aircraft immediately to the airport pavement, becoming aircraft de-icing fluid waste (ADFW). Without proper treatment, ADFW can adversely impact the local environment. Hence, airports are required by regulations to properly handle their ADFW. The partner (an airport) is seeking an adequate treatment to deal with its ADFW on-site. In this project, we are planning to develop a mobile system that integrates membrane-aerated biofilms and membrane bioreactor (MAB-MBR) for the treatment of ADFW. Preliminary experiments will be conducted to evaluate the feasibility of the technology and inform subsequent improvement of the system configuration and operating conditions. The partner will use the resultant knowledge to make evidence-based decision on its long-term ADFW management plan.

Voir la description complète du projet
Superviseur du corps professoral :

Jinkai Xue

Étudiant :

Partenaire :

Regina Airport Authority Inc.

Discipline :

Génie

Secteur :

Transport et entreposage

Université :

Université de Regina

Programme :

Accélération

Développement d’une technologie propre de comminution pour l’industrie minière : l’électrofracturation à haute puissance pulsée

L’électrofracturation à haute puissance pulsée (HPP) est une technologie permettant de fragmenter des substances rocheuses dans l’eau sous l’effet d’une série d’impulsions électriques de haute puissance. C’est une méthode innovante et non polluante en comparaison aux méthodes de broyage et concassage traditionnelles. L’objectif du projet est de comprendre les mécanismes et interactions des différents paramètres en jeux (caractéristiques du matériel, paramètres opérationnels de l’équipement). Il sera ainsi possible d’optimiser les conditions opératoires appliquées à différents types de matériel provenant de partenaires industriels, et de comparer l’efficacité énergétique de la méthode par rapport aux méthodes traditionnelles. Les résultats permettront le développement d’une base de données indiquant les paramètres optimaux d’opération de l’appareil selon le type de minerai, indiquant l’impact des propriétés physiques et électriques du matériel sur ces paramètres. Ces travaux permettront à l’organisme partenaire de déployer un service de comminution par électrofracturation à HPP à l’ensemble de ses clients et partenaires.

Voir la description complète du projet
Superviseur du corps professoral :

Jean-François Blais

Étudiant :

Partenaire :

Coalia expertise et innovation en technologie minérale et en plasturgie

Discipline :

Sciences de la Terre

Secteur :

Services professionnels, scientifiques et techniques

Université :

Université du Québec : Institut national de la recherche scientifique

Programme :

Accélération