Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

30 508 projets complétés

2882
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5105
C.-B.
825
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681
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860
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9051
ON
9491
QC
97
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586
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1141
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Projets par catégorie

Exploitation of special functions orthogonal on finitedomains of 2D and 3D lattices-Fourier expansions offunctions sampled on lattices

The advantages of digital data (signal functions) processing have made this technique a standard for processing real world analog data in many areas of life, from music industry to seismology. Stored digitally, the data also become less sensitive to physical limitations than their analog counterparts. Other advantages include straightforward low frequency filtering procedures (e.g. as required in seismology, oceanography and other environmental monitoring), as well as frequency bounding (e.g. in telecommunications, sending large bandwidth signals over a narrow bandwidth). To transform analog functions to their digital counterpart, a discretization is necessary to obtain their corresponding lattice based versions. In many problems, it is sufficient to use discrete Fourier expansions of data sampled at equidistant points of a line (in 1D), or on a square lattice formed by two orthogonal 1D lattices (in 2D).. We propose to develop and evaluate the methodology which will make use of the special symmetry properties of data that will be reflected in more efficient expansions, e.g. data sampled in 2D on a triangular lattice which will significantly improve multidimensional signal processing in terms of computational speed, memory and hardware requirements. The proposed methodology will be developed using semi-simple Lie group theory.

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Superviseur du corps professoral :

Jiri Patera

Étudiant :

Partenaire :

MIND Research Institute;OODA Technologies Inc

Discipline :

Mathematics

Secteur :

Education; Professional, scientific and technical services

Université :

Université de Montréal

Programme :

Accelerate

Development of non opioid pain therapeutics

Developing safer, more effective treatments for chronic pain has become a major area of research due to the negative side effects of opioids. This project aims to mediate the intelligent design and development of drugs, that will achieve pain relief without the detrimental side effects of addiction and respiratory depression. The proposed research will use advanced Artificial intelligence (AI) and computer modeling in order to help Zymedyne create new, viable drug-leads, as well as lead to a better understanding of how their current lead drug molecules work.

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Superviseur du corps professoral :

Gerald Werner Zamponi

Étudiant :

Partenaire :

Zymedyne Therapeutics Inc.

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Calgary

Programme :

Accelerate

Optimal mechanical design of the UV-radiation tower for Phoenix robot at the AIS – An extendable UV-radiation module for disinfecting plants

One of the practical methods for treating powdery mildew is to use a UV lighting system carried by an autonomous robot. The height of the plants can be different from one greenhouse to another or even within the same greenhouse. Hence, having a varying-height UV lighting system would be essential. . To enhance the robot’s efficiency in treating plants in narrow regions found in greenhouses, we propose to design a motorized and extendable UV lighting module. A control system would adjust the height of the UV lighting module to expose the upper parts of plants accordingly. Development of a commercial-grade system of this type would require extensive design validation and optimization against factors such as: modularity, stability, reliability, manufacturability, costs, etc. This project will focus on conducting an end-to-end system approach to the design process that would yield an optimal mechanical design for a modular mobile robot equipped with a UV lighting system.

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Superviseur du corps professoral :

Mehran Mehrandezh

Étudiant :

Partenaire :

Advanced Intelligent Systems

Discipline :

Engineering

Secteur :

Agriculture; Information and cultural industries; Professional, scientific and technical services

Université :

University of Regina

Programme :

Accelerate

Conception d’un dispositif autonome et intelligent permettant des mesures de neurophotonique de façon entièrement automatisée et à large échelle chez la souris

En recherche sur le cerveau, l’imagerie et la stimulation cérébrale sur le modèle animal sont des techniques de référence. Dans ces expériences, l’expérimentateur doit manipuler l’animal (la souris le plus souvent), ce qui réduit la qualité de données qui peuvent être collectées. Afin de dépasser cette limitation, une nouvelle stratégie d’acquisition basée sur des cages autonomes a été développé.
Un prototype a été développé par le partenaire Labeo Technologie Inc, en collaboration avec le laboratoire de Matthieu Vanni. Cependant, ce dispositif nécessite encore un certain nombre d’améliorations afin de pouvoir lui permettre d’être utilisé en remplacement des approches manuelles.
Le travail qui sera réalisé va permettre d’offrir à la recherche sur le cerveau, un nouveau type de dispositif de mesure qui va repousser les limites du savoir. Cela permettra aussi au partenaire, Labeo Technologie Inc, de sécuriser sa place de leader dans le domaine de cette nouvelle révolution technologique.

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Superviseur du corps professoral :

Matthieu Vanni

Étudiant :

Partenaire :

LabeoTech

Discipline :

Engineering

Secteur :

Manufacturing

Université :

Université de Montréal

Programme :

Accelerate

Signal profiling of 5-HT2A receptors to develop new biased ligands

G protein coupled receptors (GCPRs) are proteins found at the surface of cells are responsible for activating numerous intracellular signaling pathways and thus are involved in regulating about every physiological response. Activation of GPCRs occurs via a diverse array of stimuli as varied as photons, lipids, ions, small hormone or neurotransmitters through to larger peptidic and protein molecules. Currently, GPCRs are currently the target of up to 40% of marketed drugs. Although these drugs were originally believed to function as simple on/off switches able to start or stop GPCR activity, we now know that they produce numerous effects that may lead to undesirable responses. This new knowledge has opened the possibility of developing or identioying unique molecules aimed at specifically blocking or activating the relevant therapeutic responses while reducing deleterious effects. We have developed tools to track these pathways in tissue- and disease-relevant contexts in order to measure the effects of novel compounds and to better design drugs with improved

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Superviseur du corps professoral :

Terry Hébert

Étudiant :

Partenaire :

Diamond Therapeutics Inc

Discipline :

Life Sciences

Secteur :

Manufacturing; Professional, scientific and technical services

Université :

McGill University

Programme :

Accelerate

Centering Youth’s Perspectives on Aggression toward Family/Caregivers in Childhood & Adolescence to Inform Best Practices in Supportive Service Provision in Canada

Aggression toward family/caregivers in childhood and adolescence (AFCCA) is a serious issue that impacts all family members in complex and interrelated ways. Despite its extensive and long-term consequences, there is limited research and even scarcer supports available for young people and their families affected by this form of family violence. Expanding on a pilot project that explored parental perspectives of AFCCA in Canada, this study provides a youth-centered perspective to create impactful changes in support services that are informed by children’s rights and family-focused approaches. A national survey and several follow-up interviews will be carried out to assess the needs of youth involved in AFCCA, as well as the impacts on their siblings. Through collaboration with young people and families, and with the support of Adopt4Life, this research will help to establish the social, emotional, and mental health needs of families and provide recommendations for improving support and prevention strategies.

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Superviseur du corps professoral :

Christine Gervais;Elisa Romano

Étudiant :

Partenaire :

Adopt4Life

Discipline :

Sociology

Secteur :

Health and Related Sciences & Technology

Université :

University of Ottawa

Programme :

Accelerate

Regulating Molecular Interactions by Terahertz Signals for Revolutionized Health care Solutions

Nanosized devices operating inside the human body open up new prospects in health care. On the one hand, molecular
communication enables biological nanomachines to communicate by exchanging molecules and performing applicationdependent
tasks. On the other hand, electromagnetic (EM) nano-communication points to the Terahertz Band (0.1- 10 THz) as
the frequency range for communication among nano-biosensors. In this work, we propose a stimuli-responsive paradigm which
integrates EM and molecular communication by stimulating proteins in the human body. Our model capitalizes on the fact that
proteins act as an interface between both mediums, where triggering proteins by THz radiation impacts their conformal structure.
This results in biochemical interactions that give rise to cellular processes. As such, a new perspective on regulated protein
functions is presented targeting different engineering communities in an aim to present novel solutions that will advance the health
care sector.

Voir la description complète du projet
Superviseur du corps professoral :

Raviraj Adve

Étudiant :

Partenaire :

Northeastern University

Discipline :

Engineering

Secteur :

Education

Université :

University of Toronto

Programme :

Globalink Research Award

Development and Optimization of Freeze-dried Formulations of Ga-68 based cold kit and its performance evaluation by Radiolabeling and Animal Imaging

The student will be involved in the research and development of a novel multi-dose lyophilized vial kit for the preparation of Gallium 68Ga-DOTATOC injection used for the PET imaging of neuroendocrine tumors. This novel kit compared to the currently available ready to use injectable solution, has better shelf life and can be easily shipped to a radiopharmacy where the vial can be radiolabeled by adding the 68Ga-chloride eluted from a generator or cyclotron, and then distributed to hospitals and other nuclear medicine clinics. Availability of freeze-dried kit formulations for the preparation of 68Ga-DOTATOC is expected to increase the scope of 68Ga-based agent for PET imaging and expand the availability for more patients to receive the cancer treatment.

Voir la description complète du projet
Superviseur du corps professoral :

Hadis Zarrin

Étudiant :

Partenaire :

Jubilant Radiopharma

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

Toronto Metropolitan University

Programme :

Accelerate

Strong and transparent membranes with Janus wettability for wound closure and management

Wound dressings are indispensable in medical operation as they protect the wound from contamination by foreign matter, absorb wound exudate, and control the humidity of the wound to promote healing. To meet the requirements in wound closure and management, and convenience and comfort of users, the dressings is required to processes multiple functionalities. Optical transparency will enable appropriate alignment of edges of wounds, and visual inspection of healing progress. In this project, the researchers will develop an innovative multifunctional wound dressing using an electrospinning technique. The dressing will exhibit transparency, strong mechanical properties, and Janus wettability. Active ingredients imbedded in the dressing will promote the wound healing process. The expected outcomes of the project may lead to a marketable technology for fabricating wound dressings with potential applications in emergency departments and other prehospital applications.

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Superviseur du corps professoral :

Xuehua Zhang

Étudiant :

Partenaire :

WoundMesh

Discipline :

Engineering

Secteur :

Manufacturing

Université :

University of Alberta

Programme :

Accelerate

A Study of the Molecular Mechanisms Underlying Pediatric Medulloblastoma Mediated By YB-1

Medulloblastoma is the most common form of pediatric brain cancer with a five-year survival rate of approximately 70%, yet for some children’s survival is as low as 40%. Many of the treatment options for these patients may be effective in extending the five-year survival rate, however, quality of life issues still persist for these young patients including learning and developmental deficits. These side effects arise from damage to normal tissue in the developing brain by surgery and/or drug and radiation therapy. The goal of this project is to find novel therapeutic strategies that are effective in treating this cancer yet, do minimal harm to developing normal brain tissue. A protein called Y-box binding protein 1 (YB-1) is not found in normal tissue but is found in cancer cells including medulloblastoma. This makes this protein a good therapeutic target because inhibition of it will help kill cancer calls but not destroy normal surrounding tissue.

Voir la description complète du projet
Superviseur du corps professoral :

Poul Sorensen

Étudiant :

Partenaire :

Team Finn Foundation;BC Cancer Agency

Discipline :

Life Sciences

Secteur :

Other services (except public administration)

Université :

The University of British Columbia

Programme :

Accelerate

Improving competitiveness and sustainability of pork production through increase in feed efficiency, improved carcass quality and higher animal welfare standards by innovative application of microbiome profiling, and computed tomography

Efficient animal production with a reduced environmental impact requires healthy animals, higher performance, increased feed conversion, and the use of available nutrients. The improvement of those traits could be accomplished by understanding how the gut microbiome plays a vital role in nutrient digestion and feed efficiency. Also, applying a reliable sorting tool allows identifying pigs according to their feed digestibility capacity (near infrared spectroscopy = NIRS) and muscle deposition level (Computer tomography scan = CT scan) with minimal sample preparation, avoid serial carcass dissection and reduced time consumption, which can provide a clear picture of how their possible role is in pork growth performance and carcass/meat quality. The findings may allow us to modulate the gut microbiome to raise more efficient animals or modulate carcass/meat quality traits, as well as might be useful in identifying high-efficiency animals and facilitating the proper selection of pigs for breeding programs.

Voir la description complète du projet
Superviseur du corps professoral :

Argenis Rodas-Gonzalez;Martin Nyachoti

Étudiant :

Partenaire :

Topigs Norsvin Canada Inc.

Discipline :

Life Sciences

Secteur :

Agriculture

Université :

University of Manitoba

Programme :

Accelerate

Capacity building in small and medium enterprises for sustainability change management

The TRANSFORM Project comprises a global network of researchers located in eight different countries and 11 universities. This network is committed to building the capacity of small and medium-sized enterprises (SMEs) to accelerate the transition to sustainable, resilient, and low-carbon communities. SMEs possess great potential to shape and transform the cities and communities in which they operate. This Project will build capacity within SMEs to sustainably innovate and will help drive the transition towards resilient, inclusive, and competitive low-carbon Canadian communities.
The proposed Mitacs project seeks to foster a culture of change management to help SME senior management and leadership realign their practices and business models towards sustainability transformations. This work aligns with and contributes to Sustainable Waterloo Region’s (SWR) programs within their broader objective to embolden a culture of sustainability within businesses. The Intern will build on their knowledge and expertise about capacity building with SMEs, as well as gain soft skills that will make them competitive on the job market.

Voir la description complète du projet
Superviseur du corps professoral :

Sarah Burch

Étudiant :

Partenaire :

Sustainable Waterloo Region

Discipline :

Sociology

Secteur :

Professional, scientific and technical services

Université :

University of Waterloo

Programme :

Accelerate

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