Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

30156 projets achevés

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Projets par catégorie

Visualization of TBI Multimodal Brain Imaging Data

The increased incidence of traumatic brain injury (TBI) and its potentially serious long-term consequences have enormous clinical, societal and economic impacts in Canada. Yet despite its relatively high prevalence, TBI is one of the least understood neurological injuries. Emerging evidence shows that the effects of TBI are not transient and may be associated with significant long-term consequences on brain function. An impact to the head results in an immediate and direct insult to the brain, setting off a complex cascade of metabolic and neurochemical events. These effects can lead to long-term changes in brain physiology and ultimately impact cognitive, motor and affective function. Over a lifetime, repeated brain trauma is associated with increased incidence of multiple neuropsychiatric conditions and is a significant risk factor for developing neurodegenerative disorders.
Diagnosing TBI is currently based on clinical symptoms and neuroimaging changes as seen with a single modality such as CT or MRI to establish the presence of TBI. The main challenge is the reliance on a single brain imaging technology that provides a limited and constrained view of the complex brain injury. TO BE CONT’D

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Superviseur du corps professoral :

Mirza Faisal Beg;Naznin Virji-Babul

Étudiant :

Partenaire :

Arrowsmith Program Inc

Discipline :

Engineering

Secteur :

Education; Information and cultural industries

Université :

Simon Fraser University

Programme :

Accelerate

Development of a Real Time Bioelectric BOD Sensor for Wastewater Effluent Compliance Monitoring

The necessity of cost-efficient and reliable wastewater treatment processes has increased in order to meet more stringent levels of environmental regulations, increased system reliability requirements and tightening operational budgets. To aid in meeting these operational goals, a strong market for low-cost, high-fidelity sensor technology that can relay real-time information to system operators on all aspects of wastewater treatment system performance has developed. This project looks to advance an existing prototype biosensor to the point of marketable as an end-of-pipe regulatory Biochemical Oxygen Demand monitoring device. The success of this project will produce a technology with the capability of reducing the duration/incidence of environmental contamination events, and future development of the biosensor and platform would allow for improved management of wastewater infrastructure and treatment processes. This sensor technology will well support the aforementioned goals and reduce the impact on ecosystem and human health from incompletely treated wastewater.

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Superviseur du corps professoral :

Rob Jamieson

Étudiant :

Partenaire :

Island Water Technologies Inc

Discipline :

Engineering

Secteur :

Professional, scientific and technical services; Utilities

Université :

Dalhousie University

Programme :

Accelerate

The influence of occupant related factors on neck muscle activity during low-speed automotive collisions

Whiplash injuries of the neck as a result of automobile accidents can cause long term pain and disability for some victims. Manufacturers can design safer cars that prevent whiplash injuries by creating computer models of passengers during virtual car crashes. A key aspect of designing accurate passenger models is a deep understanding of neck muscle activation. Currently, there is a deficiency of knowledge in this area for a variety of crash scenarios. In this project, we plan to measure the activity of volunteers’ neck muscles during safe low speed collisions. The crash scenarios we will study are 1) when the driver braces against the steering wheel before a crash and 2) when a driver is not looking straight ahead before a crash. The data collected will improve our understanding of human reactions during realistic impacts and help enhance car safety.

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Superviseur du corps professoral :

Jean-Sébastien Blouin

Étudiant :

Partenaire :

MEA Forensic Engineers & Scientists

Discipline :

Physics

Secteur :

Automotive

Université :

The University of British Columbia

Programme :

Accelerate

Enhancement of signal quality in Near Infra-Red (NIR) spontaneous Raman spectroscopy using coherent detection techniques for use in real-time cancer microsurgeries

Raman spectroscopy is a compound identification technique that can be used for real-time identification of cancerous tissues during surgery. The development and clinical translation of an intraoperative surgical-guidance instrument based on this technique is the main objective of ODS Medical, a Canadian startup. However, Raman signals are intrinsically very weak thereby requiring the measurements to be done in an absolute dark environment in order to minimize interferences by sources of light in the operating room. Such a requirement is incompatible with the clinical environment: presence of visible and invisible light sources is needed to accomplish surgeon’s tasks. Using coherent detection techniques, we propose to suppress environmental interferences from the collected signal, thus allowing to acquire high quality Raman spectra with no disruption of the surgical workflow. Those techniques will be implemented on the ODS Medical system and the prototype tested in various clinical environments in order to determine optimal system operational conditions. A 6-patients pilot study will be realised where in situ intraoperative measurements are acquired during glioma surgery at Montreal Neurosurgical Institute under various ambient light conditions.

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Superviseur du corps professoral :

Frederic Lesage

Étudiant :

Partenaire :

Reveal Surgical

Discipline :

Engineering

Secteur :

Health and Related Sciences & Technology; Technology; Information and Communications Technology

Université :

École Polytechnique de Montréal

Programme :

Accelerate

Crif1 : Protein expression, purification and crystallisation

Human Crif1 is a protein with multiple functions, playing important roles in embryonic development, cellular stress, cell cycle regulation and mitochondrial membrane integrity. CRIF1 is coined to play a regulatory role in the Bone Marrow microenvironment-induced leukemia cell cycle arrest possibly through interacting with CDK2 and acting as a cyclin-dependent kinase inhibitor.
In this project, we will express human Crif1 protein in baculovirus system, purify it with affinity chromatography and followed by crystallisation. The structural elucidation of Crif1 will enhance the understanding of complex processes in leukemia cell cycle arrest and improve the strategy for drug research.

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Superviseur du corps professoral :

Sheng-Xiang Lin

Étudiant :

Partenaire :

Biotech. Boweitianchen in Sichuan Ltée;Pyrovac Inc

Discipline :

Life Sciences

Secteur :

Health and Related Sciences & Technology

Université :

Université Laval

Programme :

Accelerate

Quantifying soil nitrogen supply to reduce nitrate loading to groundwater from high intensity agricultural production areas in Nova Scotia

Understanding and measuring nitrogen supply in agricultural soils is a critical component in managing groundwater quality and minimizing impacts on the environment. Degraded water quality, primarily as nitrate contamination, is a growing concern in Atlantic Canada and agricultural fields are potential point sources. This project proposes to develop a baseline dataset from agricultural fields across Nova Scotia toward developing a soil nitrogen supply index that will help producers make better crop fertilization decisions. The outcomes of the project will provide the NS Federation of Agriculture with a clear direction for its members with respect to nitrogen management and measurement in soils.

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Superviseur du corps professoral :

Gordon Price;David Burton

Étudiant :

Partenaire :

Nova Scotia Federation of Agriculture

Discipline :

Earth science

Secteur :

Agriculture; Other services (except public administration)

Université :

Dalhousie University

Programme :

Accelerate

Genetic monitoring of a sockeye salmon repatriation to improve interactive fisheries management

Re-establishing salmonid populations to areas historically occupied has substantial potential for conservation gains, however, such interventions also risk negatively impacting native resident stocks. An on-going reintroduction of anadromous sockeye salmon (Oncorhynchus nerka) to Skaha Lake, British Columbia is succeeding, with large numbers returning to spawn. However, a recent genetic study detected strong evidence of hybridization and introgression with native kokanee (freshwater obligate form of O. nerka), yet was unable to determine what the ultimate fitness impacts are, if any, on the population health of Skaha Lake stocks. Here we propose to use morphological and genetic analyses to better understand hybridization and introgression trends between spawning reintroduced sockeye and indigenous kokanee in Skaha Lake. Results will directly inform fisheries management decisions for minimizing fitness consequences and maintaining genetic diversity within kokanee. Additionally, these data will assist in developing size thresholds for differentiating mature kokanee and sockeye, a critical input for setting recreational fishing regulations.

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Superviseur du corps professoral :

Michael Russello

Étudiant :

Partenaire :

Freshwater Fisheries Society of BC

Discipline :

Life Sciences

Secteur :

Aquaculture and Fishing; Natural Resources; Sustainability & the Environment

Université :

University of British Columbia - Okanagan

Programme :

Accelerate

An Energy Efficient Optimal Control Framework for General Purpose Flight Management Systems

The amount of emissions to the atmosphere is currently an important environmental concern as policy makers and Heads of State are starting to demonstrate a strong interest in energy efficient transportation, in particular energy efficient aircraft. The task of energy optimization is typically left to a flight management system (FMS). However, many smaller commercial aircraft, especially turboprop aircraft, still do not have an FMS due to the high cost of such a system. Furthermore, the algorithms inside a commercially available FMS are not known due to proprietary reasons. Therefore, it would be of utmost importance to develop a general purpose, open source FMS that could be installed in the iPad of pilots and used for training in the next generation flight simulators, including turboprop simulators. Developing such a general purpose, open source FMS based on optimal control techniques is the main objective of the research being proposed in this grant.

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Superviseur du corps professoral :

Luis Rodrigues

Étudiant :

Partenaire :

TRU Simulation + Training Canada Inc.

Discipline :

Engineering

Secteur :

Manufacturing

Université :

Concordia University

Programme :

Accelerate

One-Way Degassing Valve Design, Function and Application in Coffee Packaging

The purpose of this study is to gather information relating to the one-way degassing valves used within the coffee industry in order to improve upon current designs. This will be achieved through studying the opening/closing properties of commercial valves, as well as using a model system to elucidate the effects of valve components on these properties, as a function of pressure, rate of pressure change, and temperature. The study will also investigate flow behavior of different food grade sealing fluids within the model valve system, as a function of pressure and temperature. Finally, the study seeks to analyze the overall effectiveness of the degassing valve in maintaining coffee quality in selected packaging systems. This will involve measurement of select volatile compounds, freshness measures, found within the headspace of the coffee, then correlating/validating these measures to consumer acceptance through sensory evaluation.

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Superviseur du corps professoral :

Loong Tak Lim

Étudiant :

Partenaire :

O2i Ltd

Discipline :

Physics

Secteur :

Manufacturing

Université :

University of Guelph

Programme :

Accelerate

Controlling microbial processes in fracing fluids

Unconventional gas reservoirs are a great energy resource in the province of BC and Alberta and thus for Canada in general. Extracting this resource is not as straight forward as conventional gas reservoirs and requires hydraulic fracturing, also known as fracing or fracking, which has recently become a controversial topic in the public eye. This research project will examine water and fluids used in and returning from frac operations with respect to its geochemistry and bacterial populations. By knowing how bacterial population change geochemical parameters we can improve the effectiveness of the fracing and lower its environmental impact. The results of this research may therefore make fracing economically more feasible and safer for the environment.

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Superviseur du corps professoral :

Sean Crowe

Étudiant :

Partenaire :

Shell Canada

Discipline :

Earth science

Secteur :

Mining

Université :

The University of British Columbia

Programme :

Accelerate

Study of the Catalytic Effect of MFD on CuFeS2 Leaching

Bio-heap-leaching is a hydrometallurgical process used to process low grade chalcopyrite ore as the cost of alternative routes of processing and refining are not economically viable. The limitation however of the heap leaching process is the long time it takes to leach the metal and the low total recovery that can be achieved. As heap leaching being a large scale atmospheric leaching process, neither temperature nor pressure can be changed. Therefore, a viable solution is to add a catalyst that would dramatically enhance the kinetics while not being too expensive, environmentally detrimental or affect downstream process. Our discovery of MFD as catalyst fulfills all the requirements and is 100% compatible with the current heap-leaching process. Jetti resources hopes to use this technology to enhance the heap-leaching rate of chalcopyrite by at least 3 times higher than the conventional process.

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Superviseur du corps professoral :

Edouard Asselin;David Dixon;David Grant Dixon

Étudiant :

Partenaire :

Jetti Services Canada Inc

Discipline :

Engineering

Secteur :

Mining

Université :

The University of British Columbia

Programme :

Accelerate

Graphene-Oxide Strengthened Separator to Suppress Zinc Dendrites

In this research project, the separator of rechargeable hybrid aqueous batteries (REHABs) is mechanically strengthened with graphene oxide derivatives. ReHABs comprise of a lithium intercalation cathode, zinc anode and an aqueous electrolyte. One of the problems with current ReHABs is the zinc dendritic growth and propagation from the anode, which significantly reduces its operating lifetime. After cycles of charge/discharge, these dendrites grow and propagate through the separator and eventually reach the cathode, thus shortening the battery. In this project, it is expected that graphene modified separator will suppress the propagation of dendrite and hence prevent them from making contact with the cathode. This will significantly improve the lifetime of current ReHABs. Graphene oxide is chosen for this purpose due to its high mechanical strength and flexibility The partner organization will benefit from the findings of this project to scale-up the process for commercial applications of the ReHABs.

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Superviseur du corps professoral :

Pu Chen

Étudiant :

Partenaire :

Positec Canada Ltd;University of Waterloo

Discipline :

Engineering

Secteur :

Manufacturing; Professional, scientific and technical services

Université :

University of Waterloo

Programme :

Accelerate