Projets novateurs réalisés

A Data-Driven Automation Framework for Chromatography-based Purification of High-value Biotherapeutics

A critical task towards maximizing productivity in the manufacturing of biotherapeutics such as monoclonal antibodies is selecting the appropriate separation technology or sequence of technologies that meet the purity requirements of regulatory agencies (e.g. Health Canada) and maximize product recovery to reduce the overall cost per dose. The focus of this research project is two-fold. First to develop new performance monitoring tools for continuous chromatography processes. Second to optimize the downstream purification process by removing process bottlenecks and incorporating process simplifications. Sartorius, the partner for this project, will provide the state-of-the-art equipment that is needed to conduct the experimental work and student training opportunities at their R&D facilities in North America and Europe. As a global leader in biopharmaceutical manufacturing and life sciences research, Sartorius is ideally suited to translate the outcomes from this research project into the biotherapeutics manufacturing facilities of their wide network of clients.

Harrison Blade Solutions

Currently we are in the design and development stage to modify and increase the productivity of existing wind turbines with an aim to increase profitability in the green energy sector for wind farm operators.

“The scope of duties for an intern would include in depth market research to determine the value and need of our current design leading to the development of a business plan to assist us in commercialization. Key responsibilities would include detailed market research of wind turbine manufacturers, current potential competitors, assistance in a pricing model for our product and the detailed development of a step by step action plan to bring this to fruition.
Activities would encompass all of the above.”

The internship will provide knowledge and experience in both market research and business planning. The challenges we currently have that will be addressed by the internship include a lack of expertise in both market research and business planning to market.

Marketing/Accounting Intern

Grizzly Force provides on-demand staffing solutions for temporary labour needs in Greater Vancouver, BC. I will be developing overall marketing and branding strategies alongside senior management. Also, I will be following up and contacting clients for balances owing and performing a variety of accounts receivable duties.

Effets indirects de l’activité Maritimo-Portuaire : Hydrodynamique Appliquée au transport Sédimentaire et à l’Environnement (EMPHASE)

Le développement durable en milieux estuariens est largement impacté par le transport de sédiments cohésifs (vases ou boues). Or l’étude de leurs lois de transport (érosion, sédimentation) se heurte à de nombreuses difficultés à la fois pratiques (prélèvement, mise en place) et fondamentales (transition solide/liquide, rhéologie complexe).
Le transport des sédiments est un sujet qui concerne aussi bien les géologues, les hydrauliciens, les chimistes que les biologistes ou les biogéochimistes. Or, tous ces champs disciplinaires doivent avoir une connaissance parfaite des milieux physiques dans lesquels leurs objets d’étude s’inscrivent, afin d’accomplir pleinement leurs travaux. Malheureusement, dans l’état actuel des connaissances scientifiques, les prédictions du mouvement des sédiments s’avèrent imprécises. En effet, le transport de sédiments est paramétré par des lois empiriques définies uniquement en fonction d’une contrainte hydrodynamique moyenne générée sur le lit sédimentaire et de certaines caractéristiques trop générales du sédiment.

Predictive Models for Customers’ Engagement in a Small and Medium-Sized Enterprise’s Business Ecosystem Network

In the era of digitization, the success of an SME significantly depends on the active engagement with other actors (e.g., brand consumers, suppliers, influencers) in their business ecosystem. In this research project, we propose to develop an engagement model based on the business ecosystem network. These models will predict the customer engagement community association and engagement score. Our model will help the partner organization to understand the critical factor of the life cycle for any particular business on their platform. This model will also give the advantage of developing customer-focused personalized features, marketing strategies to our partner organization, thus solidifying its market position in this sector.

Mechanisms involved in triggering the rapid antidepressant effects of ketamine

Currently, the gold standard pharmacological treatment for depression typically take several weeks before becoming effective. This delayed treatment onset can be devastating because of increased rates of suicide during this wait-period. Thus, there is a need for rapid acting antidepressant drug treatments. Strikingly, a single infusion of ketamine can result in alleviation of depressive symptoms within hours. However, the effectiveness of this drug fades away over time. The intern will participate in ground-breaking research focused on understanding the neurobiological mechanisms associated with ketamine’s rapid action of onset, as well as what is occurring in the brain when it stops working. This research will be published in freely accessible journals providing Canadian clinicians with access to this information, providing them with enhanced treatment strategies. Research results can be relevant for the partner organization Janssen Canada by providing further understanding of the neurobiological mechanisms underlying the rapid action of onset of novel antidepressants.

Revalorisation des matières résiduelles par la production de mycomatériaux dans une perspective d’économie circulaire

Des découvertes récentes ont démontré que certaines racines de champignons (mycélium) peuvent être mises à profit dans la production de matériaux ayant le potentiel de remplacer le styromousse, les isolants, le bois pressé, les contreplaquées, le cuir et encore d’avantage par des matériaux de qualité supérieure. Mieux encore, ces matériaux de substitution peuvent être produits à partir de matières résiduelles présentement vouées à l’enfouissement, permettant des matériaux à impact carbone négatif.
L’objectif général du projet est d’étudier la mise en oeuvre des mycomatériaux en tant que bioprocédé d’économie circulaire par l’analyse des divers mécanismes entre la sélection des matières résiduelles, la collaboration des acteurs et les bioprocédés de production. En parallèle, des prototypes de mycomatériaux cultivés à partir des gisements de résidus/ressources d’intérêts seront produits et comparés aux matériaux face auxquels ils offrent une alternative écologique.

The Affect of Fun on the Adoption of Micromobility

This research project aims to understand what factors are driving the increased usage of shared micromobility vehicles – primarily escooters – in city centres. In particular, this research seeks to understand the notion of fun as it influences how people chose to get around within a city. The findings of this inquiry will help cities understand and in turn be better prepared in planning for and in incorporating new modes into transportation strategies. Ultimately, this research intends to help cities become more integrated and better equipped to meet demands around sustainability, congestion, affordability and increased population density. In partnering with Onpoint Strategic Group to complete this research project, the results will help them remain relevant and provide new avenues of revenue in their focus on disruptive technology.

Réinterprétation structurale du gisement de Persévérance, Camp minier de Matagami, Qc

Le Canada est un important producteur de cuivre et de zinc. Ces deux métaux sont exploités pratiquement en continu depuis les années 1950 dans le Camp Minier de Matagami en Abitibi. Le district a produit près de 5 millions de tonnes de zinc à l’aide d’une douzaine de gisements appelés « amas sulfurés ». Ces gisements sont généralement de petite taille et leur découverte est de plus en plus difficile. Les modèles d’exploration sont principalement basés sur la description des mines existantes et les premiers travaux effectués à Persévérance soulèvent un point qui n’était pas intégré dans les modèles classiques utilisés jusqu’alors : le gisement a subi plusieurs déformations. L’étude a donc pour but de comprendre les géométries issues de ces déformations ainsi que des processus qui y ont conduit. Des observations complémentaires ainsi que la réalisation d’un modèle 3D permettraient d’éclaircir cette évolution structurale.

Conception d’un procédé pour évaluer l’avancement de la phase deconstruction des projets de bâtiment afin de détecter et de mitiger tôt dansle processus les déviations.

Les nouvelles technologies émergentes dans la construction, notamment celles liées au BIM et aux simulations 4D à 7D, créent une rupture dans les méthodes de gestion et entrainent des changements majeurs dans la manière de gérer, coordonner, modéliser et planifier les chantiers, de même que la communication des informations. Cependant, lors de la planification, les méthodes traditionnelles d’ordonnancement, notamment le diagramme Gantt/Précédence, sont peu adaptées à cette nouvelle réalité. Orientées uniquement vers une représentation graphique des activités et de leurs contraintes, elles omettent plusieurs aspects essentiels pour la modélisation des opérations de construction, notamment l’emplacement des travaux, la circulation et l’enchaînent des équipes sur le chantier. Le projet de recherche se basera donc sur la Modélisation Chronographique et sa représentation spatio-temporelle des chantiers pour simuler la séquence des opérations de construction, avec comme objectif d’optimiser les échéanciers des travaux en se basant sur un calcul dynamique des taux d’occupation du chantier.

Investigation of techno-economic feasibility and environmental benefits of mine waste heat recovery systems for an underground mine in northern british columbia

Underground mining operations are very energy intensive and could require significant use of fossil fuel burning on site for electrification and heat provision, if situated in off-grid areas. Conventionally, these power plants employ diesel gen-sets that can convert only about 35% of the combustion energy to qualified work and discard about 65% of the energy generated as heat through cooling cycles and exhaust. On the other hand, due to harsh climates associated with Canadian winters, such mines require mine intake air heating (or referred as preconditioning in some literature) for preventing the mine shaft and stationary shaft units from freezing (i.e. liners, transportation equipment, ventilation fans and such). Conventionally, these mines employ large-scale fossil burning stations to generate heat at the mine intake. These systems are mostly natural gas and propane based. This project aims to investigate reutilization of the discarded heat from the power plant at the mine intake to save from fossil burning at the shaft intake burners. Earlier studies suggested that mine waste heat systems can save thousands of dollars from operational expenditures with comparably less carbon emissions.

Spence Neighborhood Association

The main areas of focus for this project will be EOS, Youth and Families, and CED. With a new all-season greenhouse set for construction in late August 2020, SNA intends to hire youth in the community to operate the facility and develop a social enterprise that will provide food security, job training, and revenue to support future SNA projects.

From this project, SNA would like to have a document that outlines the feasibility of a potential social enterprise that will meld these departments in several ways.