Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

30156 projets achevés

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Projets par catégorie

Effects of GDF11 on proliferation and stemness of mesenchymal stem cells

The development of techniques that allow the culture and differentiation of stemcells has opened new research venues and the potential for novel therapies. It has been shown that transplantation of mesenchymal stem cells from bone marrow improved heart function after myocardial infarction. Also mesenchymal stem cells regulate cardiac electrophysiological functions of cardiomyocytes, and protect the heart against cardiac arrhythmias and pathological hypertrophy.
This study investigates the effect of a growth factor GDF 11 on the differentiation and proliferation of mesenchymal stemcells. The decline of GDF 11 has been implicates in aging of the heart and skeletal muscle. The scientific question that this research aims to answer is whether GDF11 is a keyplayer in maintaining the stemcells in their undifferentiated state, thus maintaining their beneficial effect on the heart.

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Superviseur du corps professoral :

Guido van Marle

Étudiant :

Partenaire :

Harbin Medical University

Discipline :

Life Sciences

Secteur :

Education

Université :

University of Calgary

Programme :

Globalink Research Award

Expression patterns of Wnt/?-catenin signaling pathway components in colon cancer

Extensive research focused on the identification of cellular signaling pathways involved in cancers. A tumor suppressor SOX7 has been implicated in several human cancers: it has been shown to suppress the Wnt/?-catenin signaling that is highly activated in breast cancer and ovarian cancer. This study sets out to determine the role of SOX 7 and other components of the Wnt/?-catenin signaling pathway in colon cancer. Expression levels of a variety of Wnt/?-catenin pathway associated genes will be determined in a large number of clinical tissues. A high throughput genomics analysis will be used to identify correlations between expression levels and cancer type/stage and establish the putative role of these components in the development and progression of colon cancer. This work identifies target genes for the future development of cancer diagnoses and therapies.

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Superviseur du corps professoral :

Guido van Marle

Étudiant :

Partenaire :

Harbin Medical University

Discipline :

Life Sciences

Secteur :

Education

Université :

University of Calgary

Programme :

Globalink Research Award

Utilization of Machine Learning in an Automated Framework for Evaluation and Management of Information Security Risk

During the internship in collaboration with RootCellar Technologies, research will be conducted towards the design of an adaptive machine-learning solution and its integration with the existing RootCellar framework for automated evaluation and management of information security risk in small and medium size enterprise networks. The existing framework is very advanced in terms of end-point risk monitoring as well as its compliance with the NIST CVSS System. However, the part of the framework that deals with the final aggregation and ranking of individual risk-scores is suboptimal in its design and does not allow for an easy integration of feedback/expertise provided by the end-user. The objective of this research is to make the existing framework: 1) network adaptive: by arriving at the most optimal risk-score aggregation/ranking model for each particular network, and 2) time adaptive: by allowing that the risk-score aggregation/ranking model of each network be easily updated as new data becomes available. These improvements would result in a significant enhancement of the company’s present-day product. TO BE CONT’D

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Superviseur du corps professoral :

Natalija Vlajic

Étudiant :

Partenaire :

Root Cellar Technologies Corporation

Discipline :

Computer science

Secteur :

Information and cultural industries

Université :

York University

Programme :

Accelerate

Traitement adjuvant par hormone de croissance en fécondation in vitro : un essai randomisé et contrôlé.

Il a été suggéré que l’ajout d’un traitement par l’hormone de croissance (GH), pourrait augmenter les taux de grossesse en fécondation in vitro (FIV). Des études effectuées chez les mammifères, ont montré que la GH était importante pour le développement des follicules ovariens.
Notre objectif est de déterminer si le taux de grossesse lors des cycles de FIV est plus important chez les femmes recevant un traitement ou pas avec la GH.
Cette étude est comporte 528 participantes reparties en 2 groupes (traitement et contrôle) qui reçoivent un traitement pour FIV à la clinique OVO de Montréal. Le groupe traitement recevra 2.5mg de Saizen® quotidiennement par injection, dès le début du traitement de stimulation et jusqu’au jour de la ponction ovarienne.
On pense obtenir une différence de 40% entre le taux de grossesse dans le groupe traitement et le groupe contrôle.
L’ajout de GH dans les protocoles de FIV pourrait améliorer le développement et la qualité folliculaire et donc par conséquent le taux de grossesses chez les patientes mauvaises répondeuses aux traitements de FIV.

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Superviseur du corps professoral :

Carole Kamga-Ngande

Étudiant :

Partenaire :

Clinique OVO

Discipline :

Life Sciences

Secteur :

Health and Related Sciences & Technology

Université :

Université de Montréal

Programme :

Accelerate

Measuring, Tracking and Improving the Effectiveness of SBL’s Youth Space-Jobs Program

This research project will track, analyse and examine the effectiveness of Success Beyond Limit’s (SBL) Youth Space and Jobs Program. Operating in a low-income and marginalized setting, youth that attend SBL’s programming find it difficult to secure (and keep) meaningful employment. This research project will capture those experiences of these young people, identify the barriers they face with respect to employment and measure the impact of the programming they attend. The benefits of this research for SBL is specific and sophisticated evaluation of the impact of this programming for the purposes of both the fine-tuning of program delivery as well as for reporting purposes to funders and stakeholders. With an opportunity for sustained research engagement from the likes of an intern, and a comprehensive report, this will allow SBL to be an engaged and informed contributor in both municipal and provincial tables in the area of youth unemployment and community-school based interventions.

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Superviseur du corps professoral :

Carl James

Étudiant :

Partenaire :

Success Beyond Limits

Discipline :

Sociology

Secteur :

Education

Université :

York University

Programme :

Accelerate

Study on Coal and Coke Mineralogy and Development of a Model to Predict Reactivity from Mineralogy of Coking Coals

Properties of metallurgical coke are very important in production of iron using blast furnace. About 90% of the coking coals produced are used for this purpose. Coal rank was historically used to evaluate coal for production of metallurgical coke. Coke reactivity index (CRI) and coke strength after reaction (CSR) with carbon dioxide are now routinely used rank and value coking coals. The properties of the other components present in the ash may be the controlling parameters defining coke properties, which has not been studied well. In this study, we have proposed characterizing the minerals in coking coal, examine the mineralogical changes that occur during coal carbonization and coke gasification process, and finally develop a model to predict CSR/CRI of coking coals using the knowledge to be generated from this project. Findings from this project can provide the technical support for improved mining, coal washing, and blend development to make high-CSR coke. Using high-CSR coke improves blast furnaces efficiency, improves energy utilization efficiency, and reduces CO2 emissions.

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Superviseur du corps professoral :

Rajender Gupta

Étudiant :

Partenaire :

Teck Metals Ltd (Trail, BC)

Discipline :

Engineering

Secteur :

Mining

Université :

University of Alberta

Programme :

Accelerate

Prioritizing projects as a multi-criteria evaluation problem

CAE is the world-leading supplier of flight simulators and training services. Intensive competition for scarce resource exists in the multi-project environment at CAE. Without standard evaluation and objective prioritization of projects, it is difficult to allocate resources in an efficient and optimal way. From the proposed research project, CAE can expect to receive a method based on decision-making criteria that can prioritize resource allocation among multiple projects and project tasks automatically by using methods developed with multi-attribute value theory and data envelopment analysis. During the Mitacs project, the intern will acquire knowledge about decision-making, develop advance skills using Excel, improve research capability as well as gain industrial experience.

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Superviseur du corps professoral :

Vincent Thomson

Étudiant :

Partenaire :

CAE

Discipline :

Engineering

Secteur :

Aerospace; Manufacturing and Construction

Université :

McGill University

Programme :

Accelerate

Development of Additive Manufacturing Post-fusion Processes for Landing Gears

Additive Manufacturing (AM) technology demonstrates great ability of fabricating complex geometry and reducing buy-to-fly (BTF) ratio. The objective of the Héroux-Devtek R&D project is to build a relationship between post-fusion processes and material properties for additively manufactured Ti64 landing gear components. From the previous studies, promising heat-treatments were identified. In this project, studies will only focus on the four selected heat treatments. Microstructure and mechanical properties of AM components will be studied after each heat treatment at pre-determined condition (e.g., temperature, duration, inert gas, pressure, etc.). References built at the end of the studies will facilitate decision making of appropriate post-fusion processes for different AM components, in order to achieve desired material properties.

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Superviseur du corps professoral :

Mathieu Brochu

Étudiant :

Partenaire :

Héroux Devtek Inc

Discipline :

Engineering

Secteur :

Manufacturing

Université :

McGill University

Programme :

Accelerate

Auditing in the cloud, Using OpenStack Congress

In a multi-tenant cloud environment, several tenants share the same physical resources. To ensure security of tenants’ data and process, appropriate security measures should be implemented by the cloud provider at multiple layers. Particularly, appropriate controls for end-to-end network isolation must be put in place. The proposed research project aims at elaborating innovative and efficient approaches and methods to audit end-to-end network isolation in the cloud. The new knowledge and technologies that would be transferred to Ericsson through this project include a framework for automating verification of network isolation in the cloud, methods for collecting and processing data, languages and algorithms for verifying security and detecting security requirements violation. In addition to knowledge dissemination using scientific publications, the project aims at designing and implementing a research prototype that would be integrated with existing cloud management systems, such as the Ericsson Cloud Manager, as a value-added feature.

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Superviseur du corps professoral :

Lingyu Wang

Étudiant :

Partenaire :

Ericsson Canada Inc (Montreal, QC)

Discipline :

Engineering

Secteur :

Information and cultural industries; Professional, scientific and technical services

Université :

Concordia University

Programme :

Accelerate

National ID Systems and Techniques of Population Control: The development of surveillance-assisted political economy from colonial to neoliberal times in Japan

My project investigates the colonial development of Japan’s national identification (ID) systems, and the transformation of those surveillance techniques in our digital age. National ID systems identify individuals with a centralized ID number, collect and use the different kinds of personal data for multiple purposes. Those ID techniques have spread rapidly in the “war on terror” and the globalized economy. However, many of them are historically rooted in colonialism. Fingerprinting was invented in India under the British Empire. Early fingerprinted ID cards were issued in Manchuria in Northeast China, under Japan’s occupation in the 1920s-1945. Compulsory ID cards systems allowed the Japanese colonizers to identify the Chinese workers, residents and migrants, and track their movements, to eliminate potential resistance and use them as cheap labour power. Many Chinese who were categorized as “risk” to Japan’s colonization encountered the direct violence by the Japanese military. It is important to disclose the colonial origins of the ID techniques, and construct a mutual understanding of the colonial past among global communities, in order to develop the more peaceful relationships in the future. My research will bring ethical considerations to the current expansion of ID systems as surveillance.

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Superviseur du corps professoral :

David Lyon

Étudiant :

Partenaire :

Jilin University

Discipline :

Sociology

Secteur :

Education

Université :

Queen's University

Programme :

Globalink Research Award

Designing a Usable Software Lifecycle Traceability Language Part 2

Teams of specialized workers develop most software. For example, one team may specialize in the requirements that describe what the software is to do. Another team may specialize in producing the software itself. Yet another team may specialize in determining whether the software meets the desired requirements. Supporting communication between all these teams is challenging: each team is focusing on their part of the system, yet needs to have awareness of the work being performed by other teams.
This project (continuing from part 1) investigates appropriate mechanisms for providing developers access to software lifecycle information through a natural language interface. New knowledge gained from interaction and usage of the natural language interface may help the organization plan future product offerings and will potentially help improve the productivity of its own developers through increased visibility into software lifecycle information.

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Superviseur du corps professoral :

Ivan Beschastnikh

Étudiant :

Partenaire :

Tasktop Technologies

Discipline :

Computer science

Secteur :

Professional, scientific and technical services

Université :

The University of British Columbia

Programme :

Accelerate

Mobile Augmentative and Alternative Communication (AAC) Technology

The research project will involve the development of features and techniques to aid people with communication disabilities through the use of consumer mobile devices (ex. smartphones) and tablet computers. Some of the major areas of interest include: location aware vocabularies, predictive sentence construction, and support for alternative input for people that also suffer from motor control problems. This work will directly benefit the partner organization by providing enhancements and breakthrough, cutting-edge, technology features to the MyVoice commercial product. These features will give MyVoice a competitive advantage in the AAC technology market and will provide a significant benefit to users of the application.

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Superviseur du corps professoral :

Ron Baecker

Étudiant :

Partenaire :

Discipline :

Computer science

Secteur :

Université :

University of Toronto

Programme :

Accelerate

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