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29 670 projets achevés

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Projets par catégorie

Secondary cataract assessment in eyes implanted with different intraocular lenses

Cataract surgery is one of the most common surgeries performed worldwide. The incidence of posterior capsule opacification (PCO) after cataract surgery, a serious complication that affects vision and requires additional treatment, is ~30%. In this study, we will investigate differences in PCO, presence of fibronectin, and ciliary ring distortion between lenses in eyes obtained from private and public eye banks. Overall, 500 eyes from patients with intraocular lenses will be analyzed. PCO, presence of fibronectin, and ciliary ring deformation will be assessed by experienced pathologists. We believe that our results will corroborate a pilot project in which eyes implanted with Acrysof and Acrysof Natural lenses (Alcon Laboratories) will experience less PCO relative to other lens types. Alcon will be able to market their products using these data. Moreover, healthcare providers will be encouraged to increase their use of the Acrysof products, thereby reducing the the overall burden of PCO.

Voir la description complète du projet
Superviseur du corps professoral :

Miguel Burnier

Étudiant :

Partenaire :

Alcon Canada Inc;Research Institute of the McGill University Health Centre

Discipline :

Life Sciences

Secteur :

Health and Related Sciences & Technology; Manufacturing

Université :

Research Institute of the McGill University Health Centre

Programme :

Elevate

Raman micro-spectroscopy for biopsy for prostate cancer prognosis -Year two

Prostate biopsies can be difficult to interpret using standard pathology techniques. Because cancer can be fatal, the development of technologies providing complementary information could improve current pathology practice resulting in improved patient outcome. Raman micro-spectroscopy is a molecular imaging technique using backscattered light following tissue laser excitation to indicate whether or not prostate samples contain cancer cells. However, this technique is very sensitive to the molecules in chemicals used to process tissue (e.g. paraffin), which greatly limits its efficacy. We will develop a standardized protocol for the preparation of diagnostic tissues insuring the rich molecular content of Raman imaging can be fully exploited for clinical use. Raman micro-spectroscopy is a label-free technique not requiring the use of dyes or molecular reporters, thereby greatly facilitating its use. The integration of this technique would improve our capacity to establish the prognosis of prostate cancer patients and advance research supported by ICM.

Voir la description complète du projet
Superviseur du corps professoral :

Dominique Trudel

Étudiant :

Partenaire :

Institut du cancer de Montréal

Discipline :

Life Sciences

Secteur :

Other services (except public administration); Professional, scientific and technical services

Université :

Université de Montréal

Programme :

Elevate

Raman micro-spectroscopy for biopsy for prostate cancer prognosis

Prostate biopsies can be difficult to interpret using standard pathology techniques. Because cancer can be fatal, the development of technologies providing complementary information could improve current pathology practice resulting in improved patient outcome. Raman micro-spectroscopy is a molecular imaging technique using backscattered light following tissue laser excitation to indicate whether or not prostate samples contain cancer cells. However, this technique is very sensitive to the molecules in chemicals used to process tissue (e.g. paraffin), which greatly limits its efficacy. We will develop a standardized protocol for the preparation of diagnostic tissues insuring the rich molecular content of Raman imaging can be fully exploited for clinical use. Raman micro-spectroscopy is a label-free technique not requiring the use of dyes or molecular reporters, thereby greatly facilitating its use. The integration of this technique would improve our capacity to establish the prognosis of prostate cancer patients and advance research supported by ICM.

Voir la description complète du projet
Superviseur du corps professoral :

Dominique Trudel

Étudiant :

Partenaire :

Institut du cancer de Montréal

Discipline :

Life Sciences

Secteur :

Other services (except public administration); Professional, scientific and technical services

Université :

Université de Montréal

Programme :

Elevate

Identification et aide à l’implantation d’un modèle d’écosystème entrepreneurial pour l’arrondissement Saint-Laurent de Montréal

Afin d’améliorer le sort économique de l’arrondissement Saint-Laurent, DESTL souhaite créer un lien de collaboration entre les grandes entreprises, les PME et les start-ups. Ceci est dans le but de générer de la valeur ajoutée tant pour les entreprises que pour l’arrondissement. Cette tâche n’est pas sans difficulté et nécessite un exercice rigoureux de recherche afin de garantir sa réussite. Le doctorant aura donc comme tâche principale de proposer le modèle qui s’applique le mieux au contexte de l’arrondissement Saint-Laurent.

Voir la description complète du projet
Superviseur du corps professoral :

Jean-François Guertin

Étudiant :

Partenaire :

Développement Économique Saint-Laurent

Discipline :

Business

Secteur :

Administrative and support, waste management and remediation services

Université :

Université de Sherbrooke

Programme :

Accelerate

Development of nanobodies against Salmonella enterica and Campylobacter jejuni

The human pathogenic bacteria Salmonella enterica and Campylobacter jejuni are commonly found in the intestine of poultry. Consumption of infected chicken and eggs, and its derivatives, is the main and most important source of infection outbreaks in humans and causing diarrhoea, fevers and abdominal cramps. In some cases, severe diarrhea and dehydration followed by systemic spreading of these infections is life-threatening. At present no widely effective strategy is available to control both Salmonella and Campylobacter colonization of broiler chickens to prevent the infection in humans. To this end, AbCelex has developed a novel strategies of using nanobodies to control the level of Campylobacter and Salmonella in poultry meat by administering them as feed additives. Nanobodies are the smallest antibodies known in nature and are produced by members of the family Camelidae (like camels, llamas and alpacas) and sharks. This recently discovered antibodies present immunological and biotechnological advantages with respect to the conventional antibodies because they can be easily expressed in bacteria and produced in large quantities at a significantly lower cost. TO BE CONT’D

Voir la description complète du projet
Superviseur du corps professoral :

Mauricio Terebiznik;Walid Houry;Emma Master

Étudiant :

Partenaire :

AbCelex Technologies Inc

Discipline :

Life Sciences

Secteur :

Agriculture; Professional, scientific and technical services

Université :

University of Toronto Scarborough

Programme :

Accelerate

Leacock Museum National Historic Site – Conservation Study

The research project will investigate and analyze a range of existing site and building conditions that may require upgrading and/or conservation at the existing Leacock Museum, former home of Canadian humourist, Stephen Leacock. The site is a National Historic Site, located in Orillia, Ontario. Research will be focused on: barrier free accessibility; exterior cladding; exterior historic woodwork condition; energy savings; and assessment of the site as a cultural heritage landscape. The research will provide +VG Architects, the sponsoring partner, site condition data and options for potential energy conservation strategies. This will assist +VG Architects in preparing a comprehensive planning document to assist in prioritizing future capital maintenance projects for this National Heritage Site.

Voir la description complète du projet
Superviseur du corps professoral :

Robert Shipley

Étudiant :

Partenaire :

Discipline :

Engineering

Secteur :

Professional, scientific and technical services

Université :

University of Waterloo

Programme :

Accelerate

Intégration des contraintes légales sur les horaires des chauffeurs de camion dans une solution de planification de la chaine logistique

“Afin d’assurer la sécurité des transports, de nombreuses réglementations existent autour du temps de travail pour les chauffeurs de camion. Elles définissent en particulier des durées maximums de conduite, et des périodes minimums de pause et de repos. Ces réglementations, souvent complexes, varient d’un état et d’un pays à l’autre. Pour que la chaine logistique soit efficace et donc que les livraisons se fassent à moindre coût, il est essentiel que les logiciels de planification des transports puissent tenir compte de ces contraintes afin de trouver les parcours de livraison les plus efficaces dans les limites de la réglementation.Le but de ce projet est double. Il s’agit d’une part de proposer une modélisation unifiée des principales réglementations existant à l’échelle mondiale, et d’autre part d’intégrer ces restrictions dans la suite logicielle de planification des transports de JDA Software.”

Voir la description complète du projet
Superviseur du corps professoral :

Michel Gendreau

Étudiant :

Partenaire :

JDA Software Canada Ltd

Discipline :

Mathematics

Secteur :

Information and cultural industries; Professional, scientific and technical services

Université :

École Polytechnique de Montréal

Programme :

Elevate

Development of new generation of tool steels by modification in chemical composition, grain refinement, and cryogenic treatment – Year two

DK SPEC is a major producer of blades, cutters, and saws, made of tool steel, for the Canadian wood industry. In order to keep up with the stiff competition, the company has acquired some state-of-the-art heat treatment furnaces for cryogenic treatment. They have a complete cycle for machining, hardening, cryogenic and tempering cycles. They will shortly acquire a rolling machine in order to do deformation either cold or warm on the as-annealed materials before machining and final advanced heat treatment cycle. In this project new alloy will be designed and the developed knowledge and documentation during this project will help the industrial partner to implement the findings into its manufacturing process. The commitment, technical and operational contributions of company is clear indication of its interest to increase its technological level and produce high value added products.

Voir la description complète du projet
Superviseur du corps professoral :

Mohammad Jahazi

Étudiant :

Partenaire :

Dk Spec

Discipline :

Engineering

Secteur :

Manufacturing

Université :

École de technologie supérieure

Programme :

Elevate

Development of new generation of tool steels by modification in chemical composition, grain refinement, and cryogenic treatment

DK SPEC is a major producer of cutting tool steels for the Canadian wood industry. A combination of High strength, good toughness, and wear resistance determines the quality of a tool steel. In the framework of Engage, EngagePlus and MITACS acceleration projects, an advanced heat treatment cycle by cryogenic cooling at temperatures as low as -100 °C was developed. The application of the above cycle resulted in a 75% reduction in processing time and improvement in wear resistance (+20%). However, in-depth thermodynamic and microstructural studies in the last three years showed that the chemical composition and microstructure of conventional tool steels do not meet the entire requirements for the cryogenic treatment. Therefore, the main objective of the project is to study new alloys compositions as well as new microstructure modification methods (e.g. cold or warm deformations) prior to the cryogenic treatment to achieve the superior mechanical properties required by industry.

Voir la description complète du projet
Superviseur du corps professoral :

Mohammad Jahazi

Étudiant :

Partenaire :

Dk Spec

Discipline :

Engineering

Secteur :

Manufacturing

Université :

École de technologie supérieure

Programme :

Elevate

Approches génétiques à haut-débit appliquées au métabolisme microbien pour la prévention et le traitement des défauts de saveur du sirop d’érable

“Des métabolites présents dans la sève d’érable sont responsables d’un défaut de saveur de plus en plus préoccupant pour l’industrie acéricole, le défaut de « bourgeon ». Les objectifs du projet sont d’explorer les voies de traitement microbiologique possible dans la sève ainsi que dans le sirop d’érable:1. Étudier par des approches de séquençage à haut-débit, le métabolisme de divers microorganismes dans de la sève de qualité en contraste avec de la sève de « bourgeon » pour identifier les microorganismes ayant le meilleur potentiel pour métaboliser les précurseurs de défauts de saveur et ainsi neutraliser ces défauts avant leur apparition.2. À l’aide d’outils génétiques, utiliser le métabolisme de la levure comme rapporteur pour identifier des enzymes capables de dégrader les molécules responsables de divers types de défauts de saveur dans le sirop d’érable.”

Voir la description complète du projet
Superviseur du corps professoral :

Christian Landry

Étudiant :

Partenaire :

Centre ACER

Discipline :

Life Sciences

Secteur :

Agriculture and Food; Biotechnology

Université :

Université Laval

Programme :

Elevate

Primary care nursing and prenatal education amongst pregnant woman in rural India

In India, maternal mortality rate is one of the highest in the world. It is therefore crucial to improve health care for pregnant women to prevent pregnancy complications, premature births and maternal and infant deaths. As the nurse is one of the key health professionals interacting with pregnant women, it is essential to redefine her role in health education and prevention of
infectious diseases. Infectious diseases such as hepatitis A and E are transmitted through the consumption of contaminated water. Therefore, the nurse and other health professionals should educate women to healthy water sterilization habits. Given this context, the outcomes of this project will be to define the role of the nurse in rural maternal health care, identify the major
barriers to access clean water for pregnant women in rural areas of Gujarat, and develop a health promotion intervention proposal for pregnant women of Gujarat raise awareness about the benefits of using clean water.

Voir la description complète du projet
Superviseur du corps professoral :

Bilkis Vissandjée

Étudiant :

Partenaire :

Indian Institute of Public Health Gandhinagar

Discipline :

Sociology

Secteur :

Université :

Université de Montréal

Programme :

Globalink Research Award

Using Mobile Phones for Compliance to TB Medication: Applying a Gender Perspective

India is the country with the greatest burden of tuberculosis (TB), a very deadly infectious disease. Yet, TB is treatable with a drug regimen. However, as the treatment is very demanding, it is challenging even the most enthusiastic patient to remain compliant. Innovative strategies, such as the use of mobile phones, could complement existing methods used to increase TB
compliance. Nurses may emerge as leader in the development and pilot test of such populationbased interventions. As gender is one of the factors that may influence adherence, the expected outcomes are to identify best practices, highlighting the role of primary care nursing associated with improved TB treatment compliance while using mobile phones, with a gender perspective, and to have a better understanding of the challenges in the application of the best practices identified, in rural settings.

Voir la description complète du projet
Superviseur du corps professoral :

Bilkis Vissandjée

Étudiant :

Partenaire :

Indian Institute of Public Health Gandhinagar

Discipline :

Sociology

Secteur :

Université :

Université de Montréal

Programme :

Globalink Research Award

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