Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

31 620 projets complétés

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856
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Projets par catégorie

Evolutionarily guided rational design of vaccines, antibody therapeutics, and accurate serological assays for COVID-19

Efforts to contain the spread of COVID-19 have failed and we face an ongoing pandemic that has already infected millions of people world-wide. There are currently no drugs or vaccines that have been approved for the treatment of COVID-19, and existing blood tests for immunity suffer from inaccuracies. Moreover, since antibody or vaccine development can take several years, most of the treatments developed now by screening recovered COVID-19 patient serum to the virus will likely suffer from the rapid mutation of the virus, and may not be effective for future coronavirus mutants. This is the main reason why we cannot use therapies developed for SARS-CoV from the 2003 outbreak to the current pandemic. This project will develop evolutionarily-guided therapeutics and accurate blood tests that will account for future mutations in the virus, which could be used both against the current strain, and may also be able to prevent future pandemics.

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Superviseur du corps professoral :

Colin Gay;Steven Plotkin

Étudiant :

Partenaire :

ProMIS Neurosciences

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

The University of British Columbia

Programme :

Accelerate

COVID-19 and Bridging the Social and Physical Gap: Dynamic Digital Resources to Meet the Mental Health Support Needs of Children, Youth, and Families

The COVID-19 pandemic has challenged us with social isolation, financial uncertainty, and daily life disruptions. Parents and children may be uniquely impacted as parents attempt to navigate the stressors of working from home, caring for children, and, potentially, caring for their elderly parents and other family members. Children and youth, in turn, are influenced by parental anxieties that may exacerbate the child’s/youth’s own mental health concerns. The Centre for Rural and Northern Health Research (CRaNHR) is teaming up with MLD Solutions and child/youth-serving organizations to convert static resources to a dynamic client experience using the Mozaik.Global platform. Mozaik.Global has a broad range of features to easily incorporate digital material, develop quizzes, add gaming features, etc., and record keystrokes, swipes, and clicks to build a rich and vibrant picture of the users’ engagement with the digital content. The team will examine how engagement with digital mental health content best meets the support needs of children, youth, and family members during the social restrictions imposed during the COVID-19 pandemic.

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Superviseur du corps professoral :

Diana Urajnik

Étudiant :

Partenaire :

MLD Solutions Inc

Discipline :

Sociology

Secteur :

Information and cultural industries

Université :

Laurentian University

Programme :

Accelerate

Consumer Access to Personal Health Information for Asthma Self-Management

The Centre for Global eHealth Innovation (UHN) is leading the development of a mobile web
application for asthma self-management on behalf of Ontario Lung Association, in a project
funded by Canada Health Infoway. The internship will involve the research and development
of the user-interface of this novel application, which can be accessed by users via standard
browsers on desktops and laptops to across a range of mobile devices such as smartphones
and tablets. The application aims to enhance collaborative management of asthma between
patients, caregivers, and healthcare providers, by leveraging various electronic resources
and tools for disease management, providing access to personal health information and
asthma care plan information, and allowing collection of user-entered asthma information.
This involves support for various features that allow for personalized management of their
asthma condition. This application will fill in the present void of a technological solution for
asthma self-management and will empower patients to become actively involved in their
treatment plans. It will Significantly benefit….TOBECONT’D

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Superviseur du corps professoral :

Ron Baecker

Étudiant :

Partenaire :

Centre for Global eHealth Innovation;TELUS Health Space

Discipline :

Computer science

Secteur :

Professional, scientific and technical services

Université :

University of Toronto

Programme :

Accelerate

Les effets de la pandémie COVID-19 sur la vitalité culturelle du Quartier des spectacles à Montréal

L’étude proposée déterminera l’incidence des activités culturelles et créatives sur le développement du Quartier des spectacles à Montréal. La démarche permettra d’identifier et d’analyser les initiatives culturelles portées par divers acteurs locaux, dans une perspective de développement local. La vitalité culturelle du Quartier des spectacles sera mise en perspective dans le contexte de la pandémie du COVID-19 et les effets que celle-ci pourrait avoir sur le secteur culturel du territoire. Les résultats de la recherche permettront aux intervenants de mieux cibler leurs actions sur le terrain et de mieux orienter leurs objectifs et leur mission. Finalement, l’étude apportera un portrait de la vitalité culturelle du quartier qui permettra aux acteurs locaux d’inscrire ce thème dans le processus de transformation que traverse le territoire.

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Superviseur du corps professoral :

Juan Luis Klein

Étudiant :

Partenaire :

Synapse C

Discipline :

Sociology

Secteur :

Information and cultural industries; Professional, scientific and technical services

Université :

Université du Québec à Montréal

Programme :

Accelerate

Hunt for the Super-Spreaders — A Complex Networks Approach

Contagious diseases, such as SARS and COVID-19, bring a large amount of damage to human’s life and world economy. Pathogens spread among individuals through the contact network. It is observed that most social networks show a power-law degree distribution, implying that hubs exist in these networks. Finding underlying super-spreaders (hubs) and isolating or immunizing them can decrease the pathogen spreading dramatically. In this project, we propose a new framework based on “Biased Friendship Paradox” (BFP) to identify latent super-spreaders effectively and efficiently with- out global knowledge of the network. Using this method to guide isolation and immunization will save a large amount of time and resources.

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Superviseur du corps professoral :

Yuanzhu Chen

Étudiant :

Partenaire :

NASDAQ Canada Inc

Discipline :

Computer science

Secteur :

New and Digital Media; Health and Related Sciences & Technology; COVID-19 related Research and Solutions

Université :

Memorial University of Newfoundland

Programme :

Accelerate

Implementation and evaluation of an online tool to support the screening and triage of people with manifestations of psychological deterioration in the context of a pandemic

In the context of a pandemic, one of the main challenges is the difficulty of meeting the needs of the population while taking into account the shortage of resources. Thus, it is imperative to innovate and create strategies that are both dynamic and interactive, in an effort to better identify those individuals most at risk and to prioritize needs, given limited resources. The aim of this project is to create a tool to identify the intensity of manifestations of anxiety, depression and post-traumatic stress in people to guide them towards the right health management strategies, in accordance with their level of risk. In addition, this project can be used as screening and triage system for health services in order to improve the effectiveness of their responses according the level of psychological distress of their populations.

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Superviseur du corps professoral :

Catherine Briand;Marie-Michèle Lord

Étudiant :

Partenaire :

InoHaus

Discipline :

Life Sciences

Secteur :

Information and cultural industries

Université :

Université du Québec à Trois-Rivières

Programme :

Accelerate

Impact of Livestock Grazing on Grassland Herpetofauna

Grasslands cover approximately one third of the Earth’s surface but are among the most threatened and least protected habitats. Livestock grazing is one management strategy to restore degraded grassland ecosystems, but little is known about the effect of grazing on grassland reptiles and amphibians (herpetofauna). World-wide, herpetofauna are in decline and may be particularly susceptible to impacts from grazing. The goal of this project is to understand how grazing in mixed-grass prairies affects grassland herpetofauna species-at-risk using coverboard arrays to locate herpetofauna and quadrat surveys to characterize plant diversity. We will determine: 1) how grazing affects biotic (plant and herpetofauna species) and abiotic (thermal and moisture) environments, and 2) how biotic and abiotic environments change on a gradient from forest edge to the center of a mixed-grass prairie. Understanding the potential impacts of grazing will assist Nature Conservancy Canada (NCC) in management of mixed-grass prairie habitat throughout western Canada.

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Superviseur du corps professoral :

Pamela Rutherford

Étudiant :

Partenaire :

Nature Conservancy of Canada

Discipline :

Life Sciences

Secteur :

Agriculture and Food; Natural Resources; Environmental Science and Technology

Université :

Brandon University

Programme :

Accelerate

Broad Spectrum CoV Therapeutic; rhACE2 Immunoadhesin to treat COVID19

Over the last decade, multiple pandemic events have highlighted the vulnerability of the world to existing and emerging infectious threats. Currently, COVID19 has infected >4M people resulting in >300K deaths. Although there are candidate drugs in development, the projected term until an effective COVID therapy or vaccine is available is projected to between 1-2 years. COVID19 marks the third coronavirus outbreak (preceded by SARS and MERS) within the last 20 years and suggests spillover of animal to human coronavirus will occur again. Therefore, in addition to conventional practices (social distancing and quarantining), other strategies to prevent death and spread are needed. The ability to have a ready-made coronavirus solution in place could provide an effective tool in the early phases of future outbreaks and protect front line workers and naïve populations. The Therapeutics Business Unit (TxBU) within Emergent BioSolutions Canada Inc. is proposing a proof-of-concept program to address current and future Coronavirus infections. Chimeric variants of recombinant human ACE2 receptor will be evaluated and downselected to a lead candidate(s) to assess efficacy in vivo for treatment and prophylaxis modalities (against SARS-CoV-2 and SARS) with implications for addressing future coronavirus outbreaks.

Voir la description complète du projet
Superviseur du corps professoral :

Jason Kindrachuk;Peter Pelka

Étudiant :

Partenaire :

Emergent BioSolutions

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Manitoba

Programme :

Accelerate

Monitoring the Impact of COVID-19 Isolation Policies on Public Wellness using IoT – A Public Health and Work from Home Perspective

Social isolation is having a significant impact on the quality of life, physical activity, and sleep patterns of our population. While self-isolation and social distancing provide the most successful method for limiting the progression and spread of infectious diseases like COVID-19, we often overlook the impact of these rules on our population. This impact is also observed in the quality of the work environment available for employees working from home, where they often lack the necessary equipment and conditions to comfortably and safely work from home.
Through the use of data ecosystems developed at the UbiLab, we propose to monitor the impact of quarantine rules on household-level and individual-level physical activity, sleep, mental health, and work-related stressors and ergonomics.
During Phase 1, from a public health perspective, the proposed ecosystem would be useful in understanding the impact of COVID-19 in our population, monitoring the ongoing impact and the changes in our behaviours caused by public policies implemented. In Phase 2, our team will explore the use of this data to better inform work from home guidelines.

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Superviseur du corps professoral :

Plinio Pelegrini Morita

Étudiant :

Partenaire :

Thinktum

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Waterloo

Programme :

Accelerate

Probiotic Reduction of Biofilm and Viral and Microbial Spread in Built Environments through Air Purification and Humidity Control

Origen Air and the University of Victoria (UVic) will construct a controlled test environment inside a seven-meter shipping container with a greenhouse bio filter installed on the roof. It will connect to a heating, ventilation, and air conditioning (HVAC) system servicing the interior of the shipping container. The system will include anti-viral surfactants and air purification/humidity control technologies, including probiotic fogging to destroy biofilms, genetically engineered pothos ivy biofiltration, activated carbon filtration, ultraviolet disinfection, and HEPA particle filtration. This experimental research initiative will focus on the reduction of viral transmission through controlled humidity, air purification, and surface sanitation to reduce the spread of COVID-19 and other viruses.

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Superviseur du corps professoral :

Phalguni Mukhopadhyaya

Étudiant :

Partenaire :

Origen Air

Discipline :

Engineering

Secteur :

Manufacturing

Université :

University of Victoria

Programme :

Accelerate

Development of Thin Polymer Strips for COVID-19 Vaccine Delivery

This project will develop thin polymer strips that dissolve rapidly in the mouth and can deliver a therapeutic payload. Specifically, the proposed strips will be loaded with vaccine particles that can be delivered directly to the bloodstream via the sub-lingual mucous membranes. It has been previously shown that sub-lingual vaccination is effective for a number of infections. We believe that, even after a vaccine for the current pandemic is found, administration of the vaccine using traditional methods will take a very long time. The proposed polymer strips will allow people to become vaccinated in a rapid and convenient manner, without the need for medical staff.

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Superviseur du corps professoral :

Alex Adronov

Étudiant :

Partenaire :

Rapid Dose Therapeutics Corp.

Discipline :

Physics

Secteur :

Information and cultural industries

Université :

McMaster University

Programme :

Accelerate

Development of wearable QR-RFID trackers for prevention of spreading of COVID-19

Social distancing and case tracking are effective steps to prevent the further spread of Covid-19 and prepare for the recovery of economy. QR code scanning is applied in many countries for case tracking purpose; however, as a smart phone is required and concerns of the privacy have raised, a simple-to-use and cost-effective approach based on non-contact functional system is proposed. By combining QR code with chipless RFID in one tag, a personal information can be read and uploaded automatically before entering into crowded places. Thanks to the sensing function of RFID, too close contact can be detected, and the system will remind or warn the person. In this project, a printed-electronics-solution building upon a react-on-demand (RoD) inkjet printing technology is used for printing chipless RFID. This method not only provides high resolution manufacturing of silver traces through on-site synthesis, but also lower the cost for the whole tag.

Voir la description complète du projet
Superviseur du corps professoral :

Jun Yang

Étudiant :

Partenaire :

Canadian Two-Dimensional Barcode Technology Inc.

Discipline :

Engineering

Secteur :

Information and cultural industries

Université :

The University of Western Ontario

Programme :

Accelerate