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Projets par catégorie

The Role of Cannabinoid Receptors in Craniofacial Pain – Year Two

Pain in the craniofacial region is one of the more complex and difficult to treat conditions for patients and clinicians. Current treatments are complicated by limited efficacy and considerable side effects. Many of these conditions show greater prevalence in women than men, but there is a lack of basic research utilizing female animals. Recent advances
in cannabinoid pharmacology have renewed hope in cannabis-based treatments for chronic pain. However, whether the endocannabinoid system can be recruited to treat specific craniofacial pain conditions remains unclear. Here we propose to investigate the role of cannabinoid receptors in three animal models of chronic craniofacial pain conditions including neuropathic pain, muscle pain and arthritis of the jaw joint in the female rats. InMed Pharmaceuticals is currently developing cannabis-based therapies for pain and the result of this study will help them to identify new potential markets as well as guide future research directions.

Voir la description complète du projet
Superviseur du corps professoral :

Brian Cairns

Étudiant :

Partenaire :

InMed Pharmaceuticals Inc

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

The University of British Columbia

Programme :

Elevate

The Role of Cannabinoid Receptors in Craniofacial Pain

Pain in the craniofacial region is one of the more complex and difficult to treat conditions for patients and clinicians. Current treatments are complicated by limited efficacy and considerable side effects. Many of these conditions show greater prevalence in women than men, but there is a lack of basic research utilizing female animals. Recent advances
in cannabinoid pharmacology have renewed hope in cannabis-based treatments for chronic pain. However, whether the endocannabinoid system can be recruited to treat specific craniofacial pain conditions remains unclear. Here we propose to investigate the role of cannabinoid receptors in three animal models of chronic craniofacial pain conditions including neuropathic pain, muscle pain and arthritis of the jaw joint in the female rats. InMed Pharmaceuticals is currently developing cannabis-based therapies for pain and the result of this study will help them to identify new potential markets as well as guide future research directions.

Voir la description complète du projet
Superviseur du corps professoral :

Brian Cairns

Étudiant :

Partenaire :

InMed Pharmaceuticals Inc

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

The University of British Columbia

Programme :

Elevate

Investigation of new analytical approaches relating to Dried Blood Spot samples collectedon collection cards and analysed by GC/MS based detection

The current approach for testing compounds of interest in blood such as drugs or nutrients involves drawing blood samples into vials that then require refrigeration prior to testing. Since transportation to remote laboratories is challenging, people need to go into medical labs to have their blood tested. This research will develop improved techniques that enable blood samples to be collected from a finger prick onto a specially designed card that eliminates biohazards and makes the sample stable at room temperature so that it could be mailed or sent by courier to a lab. This work will develop collection cards for other samples such as wine or juice. Furthermore, new approaches will be developed that allow solid samples such as tissues or food samples to be extracted onto cards for convenient analysis on DBS automated analysers. In short this research will improve access to blood testing and other materials.

Voir la description complète du projet
Superviseur du corps professoral :

Liang Li

Étudiant :

Partenaire :

Supra Research and Development

Discipline :

Physics

Secteur :

Professional, scientific and technical services

Université :

University of Alberta

Programme :

Elevate

Data Mining of Urban Mobility Pattern Using Taxi Trajectory Data

Urban mobility results from human movements from one region to another for interaction such as working, trading goods and other social events. Urban mobility has caused not only urban prosperity, but also some problems in the urban system, such as congestion, air pollution, energy consumption, public health and disease transmission. Therefore, understanding urban mobility is very important for urban planning and management. Urban mobility usually has certain patterns such as origin-destination pattern and spatio-temporal pattern. This project aims to discover the potential mobility patterns based on taxi trajectory data from Shenzhen city, China. Firstly, the entire city is partitioned into several regions. The functions of each region will be studied using a statistical method, and be represented as a vector; Secondly, regions will be clustered into several categories, and regions with similar functions will be grouped together, and finally it aims to discover frequent origin-destination pattern among regions and spatiotemporal pattern based on the probability distribution of taxi pick-up time and location.

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Superviseur du corps professoral :

Xin Wang

Étudiant :

Partenaire :

Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences

Discipline :

Computer science

Secteur :

Education

Université :

University of Calgary

Programme :

Globalink Research Award

Algorithme de jumelage multimodal pour l’optimisation des options de covoiturage dynamique de la plateforme Netlift

Pour faire face à la congestion en milieu urbain, de plus en plus de citoyens se tournent vers le covoiturage pour permettre de partager leurs véhicules pour effectuer des déplacements vers leur lieu de travail. Il existe des plateformes web permettant aux gens de trouver des itinéraires communs, mais ces sites sont limités, car il est rare de trouver deux personnes qui ont une origine et une destination vraiment communes. Dans ce projet, nous proposons de développer, en collaboration avec l’entreprise Netlift, un algorithme d’appariement conducteur-passager dynamique prenant en compte la multimodalité des déplacements. Ainsi, l’algorithme proposera des possibilités de jumelage en temps réel, non seulement sur le réseau routier (en voiture), mais également sur le réseau de transport en commun et d’autres services de transport

Voir la description complète du projet
Superviseur du corps professoral :

Catherine Morency

Étudiant :

Partenaire :

Netlift

Discipline :

Engineering

Secteur :

Professional, scientific and technical services

Université :

École Polytechnique de Montréal

Programme :

Accelerate

Innovative Use of Compost at Brady Road Resource Management Facility

The proposed research aims to develop general design parameters needed to optimize a large-scale landfill biocover for countering landfill methane emissions at Brady Road Resource Management Facility (BRRMF). The intern will conduct column studies aimed at determining the optimum combination of yard waste and leaf compost and biosolids compost for facilitating the growth of methane oxidizing bacteria known as “methanotrophs” in the landfill cover. Test condition variables will include full and non-enrichment, and the effects of temperature, moisture, freeze/thaw, and methane loads with removal examined both horizontally and vertically within the columns. The partner company KGS Group of Winnipeg has established itself within the landfill management areas for the City of Winnipeg Landfills. The proposed column experiments will prove the concept of an engineered biological cover at BRRMF and allow KGS Group to properly implement a full-scale biocover application to a section of landfill cell at the site.

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Superviseur du corps professoral :

Qiuyan Yuan

Étudiant :

Partenaire :

KGS Group

Discipline :

Engineering

Secteur :

Sustainability & the Environment; Environmental Science and Technology

Université :

University of Manitoba

Programme :

Accelerate

Investigating the use of public food forests in urban food systems planning

Public food forests can be an important way to increase urban resilience, sustainability, and food security. The food forest, or forest garden, is an edible landscape designed for food production. This research investigates how publicly-accessible urban food forests are currently being utilized to enhance food production and resilience. By reviewing existing examples, this research seeks to identify key models for design, participatory decision-making, and ongoing management of food forests on public land. This research will inform Integrated Living Landscapes of recent developments in this field and assist the Company in communicating the strengths, benefits, risks, opportunities, and best practices of public food forest design to potential clients. A summary of recommendations and presentation of key models will be given to the partner organization, Integrated Living Landscapes, to inform future food systems planning and design with municipal and institutional partners within the City of Victoria.

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Superviseur du corps professoral :

Duncan Taylor

Étudiant :

Partenaire :

Integrated Living Landscapes

Discipline :

Sociology

Secteur :

Professional, scientific and technical services

Université :

University of Victoria

Programme :

Accelerate

By the North with the North: Community Building in Northern Saskatchewan

This unique research project, undertaken by Master of Northern Governance and Development (MNGD) students, contributes significantly to our understanding of the North. The research focuses on community-based responses to rapid economic, social, and environmental changes and the development of the local capacity to respond. The analysis is collaborative, involving key stakeholders at the community and multi-community levels, and is informed by their values and interests. This project is aptly named as it is truly by the north with the north, with a focus on the north’s interests in building sustainable, healthy, educated communities with improved economic and social outcomes.

Voir la description complète du projet
Superviseur du corps professoral :

Robert Patrick;Ken Coates;Carin Holroyd;Lee Swanson;Hayley Hesseln

Étudiant :

Partenaire :

Cameco Corporation (Saskatoon, SK);University of Saskatchewan

Discipline :

Sociology

Secteur :

Mining

Université :

University of Saskatchewan

Programme :

Accelerate

Development of Efficient Cathodes for the Chlorate Process

The proposed project focuses on the research & development of efficient electrode materials for use in the Chlorate Process that produces bleaching agents used in the pulp & paper industry. As an electrochemical process, significant portions of the production costs of chlorate are attributable to electrical power consumption; therefore, improvements in energetic efficiency would result in appreciable reductions in production costs. Major energetic losses arise from inefficient electrode materials and the instability of catalytic coatings on the electrodes resulting from the harsh operating conditions. Our research aims to identify stable and efficient electrode materials using the techniques and expertise developed by the partner organization, FireWater Fuel Corp., for related hydrogen production applications. FireWater Fuel will benefit from the ability to attract highly trained personnel to our team in order to accelerate the commercialization of our catalyst technologies.

Voir la description complète du projet
Superviseur du corps professoral :

Todd Christopher Sutherland

Étudiant :

Partenaire :

Click Materials Corp

Discipline :

Physics

Secteur :

Advanced Manufacturing; Nanotechnology; Sustainability & the Environment

Université :

University of Calgary

Programme :

Elevate

Impacts of Environmental Change on Subsistence Land Use

My internship focuses on the creation of a weighted scale that ranks different types of environmental disturbances, both natural (i.e. wildfires) and anthropogenic (i.e. seismic activity), by the level of transformation they incur in arctic tundra ecosystems. Currently, there is a lack of a widely used ranking system to help understand which types of environmental disturbances in the arctic are most severe. This project will analyze existing data and literature to create a weighting system that evaluates the severity of environmental perturbations and the amount of time that each disturbance persists on the land. This will allow for the evaluation of environmental impacts in relation to one-another. This is of direct relevance to my partner organization, Kwusen, as Kwusen consults on a number of projects that encounter similar types of ecological disturbances in other regions of Canada. Therefore, my work has the potential to inform current and future research that Kwusen engages in

Voir la description complète du projet
Superviseur du corps professoral :

Trevor Lantz

Étudiant :

Partenaire :

Kwusen Research and Media Ltd

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Victoria

Programme :

Accelerate

Feature-based 3D Robot Motion Programming

Path programming for various robot applications in the industry involves precise specification of data for coordinated control of the different moving parts, arms, limbs, joints, etc. in order to optimally perform application specific tasks. Robotmaster™ software from Jabez Technologies is used to plan and simulate robotic operations and generate robot code for industrial applications. Robotmaster recently won the Robotics Game Changer Award for enhancing the way in which robots are programmed, facilitating their adoption in new and technologically emerging applications. Presently, Robotmaster does not have 3D CAD/CAM capabilities. This severely restricts the scope of its applicability. The main objective of this project is to enhance Robotmaster to enable specialized operations planning and programming for robot tasks in full 3D, such as cutting, trimming, spray painting, machining, welding, etc. A feature-based path programming strategy is being investigated and adopted. Various issues related to specialized path programming will be investigated and suitable solutions implemented to enhance Robotmaster with these capabilities, with improved performance and wider scope of applications. This could help significantly increase the customer base for Robotmaster and benefit Jabez Technologies, Quebec and Canada.

Voir la description complète du projet
Superviseur du corps professoral :

Brigitte Jaumard

Étudiant :

Partenaire :

Hypertherm Robotic Software

Discipline :

Computer science

Secteur :

Professional, scientific and technical services

Université :

Concordia University

Programme :

Accelerate

The application of Dried Blood Spot samples to Nutraceutical Metabolomics studies and related applications using LCMS based detection

The current approach for testing compounds of interest in blood such as drugs or nutrients involves drawing blood samples into vials that then require refrigeration prior to testing. Since transportation to remote laboratories is challenging, people need to go into medical labs to have their blood tested. This research will develop improved techniques that enable blood samples to be collected from a finger prick onto a specially designed card that eliminates biohazards and makes the sample stable at room temperature so that it could be mailed or sent by courier to a lab. This work will develop blood collection cards that make analysis simpler and more efficient. Ultimately, individuals may be able to collect their own blood samples at home and send these to labs for analysis rather than needing to go to a lab to have their blood drawn. In short this research will improve access to blood testing. Word count:

Voir la description complète du projet
Superviseur du corps professoral :

Liang Li

Étudiant :

Partenaire :

Supra Research and Development

Discipline :

Physics

Secteur :

Professional, scientific and technical services

Université :

University of Alberta

Programme :

Elevate

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