Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

30 508 projets complétés

2882
AB
5105
C.-B.
825
MB
681
NL
860
SK
9051
ON
9491
QC
97
PE
586
NB
1141
NS

Projets par catégorie

Development of peptide-based probes as imaging and targeting agents for glioblastoma therapy

Glioblastoma (GBM), the most aggressive primary brain tumors in adults, is feared for its near uniformly fatal prognosis. Due to its infiltrative nature, surgery alone is ineffective in disease eradication. We originally identified abnormal cancer stem cells called brain tumor-initiating cells (BTICs) that lead to the formation of this brain tumor. These BTICs are known to be resistant to current chemoradiotherapy and act as disease reservoirs that contribute to recurrence. Using clinically relevant human GBM BTIC models from treatment resistant recurrent tumors, our collaborator Dr. Steve Robbins employed an unbiased combinatorial phage-display biopanning strategy to isolate peptides that home in vivo to disease reservoirs within GBM; especially the invasive and stem-like populations. We aim to develop these peptides for molecular imaging and clinical targeting of treatment resistant GBM BTICs, with the ultimate goal of improving patient outcomes.

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Superviseur du corps professoral :

Sheila Kumari Singh

Étudiant :

Partenaire :

Arch Biopartners

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

McMaster University

Programme :

Elevate

Action-driven 3D Indoor Scene Modeling

3D indoor scenes are ubiquitously needed in the virtual world, e.g. 3D games, movies and virtual reality. These scenes provide the essential virtual environments for 3D characters to perform daily activities and tasks. Current scenes on public available datasets, e.g. Trimble 3D warehouse, are usually clean and well organized, and might not be sufficient to serve as the realistic environment needed in applications that involve human interaction. In this project, we aim to produce scenes which are like having been used or interacted by human. We propose to learn human actions from various online data sources, e.g. public available RGB-D datasets, online video streams or still images, and apply the learned actions to generate “messed-up” indoor scenes. By analyzing how human interacts with indoor objects, we also aim to build a generic action model that could be applied to different scene categories and use the model for action-driven scene understanding and modeling in the future.

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Superviseur du corps professoral :

Richard Zhang

Étudiant :

Partenaire :

Microsoft Research Asia;Tsinghua University

Discipline :

Computer science

Secteur :

Education

Université :

Simon Fraser University

Programme :

Globalink Research Award

Fundamental Study on Synthesis Method with Zero Waste for LiNi0.8Co0.15Al0.05O2 Cathode Materials in Li ion Batteries used for Electric Vehicles

An innovative, zero-waste synthesis process has been proposed by the partner organization and the research team for the production of high capacity cathodes for lithium-ion batteries, such as LiNi0.8Co0.15Al0.05O2. However, many fundamental issues need to be answered related to the process and its impact on the structural and electrochemical properties of the synthesized material. The scope of the project includes (1) studying the detailed reaction mechanism of the process; (2) investigating the microstructure and surface properties of the synthesized materials under various conditions using X-ray absorption near edge structural analysis, SEM, TEM, BET, etc, and (3) evaluating the electrochemical performance of the synthesized materials in lithium-ion cells to establish the relationship between the material synthesis process conditions and their performance. This work will help the partner company to gain knowledge in the fundamentals of the process and material properties and therefore help them in their scale up and commercialization process.

Voir la description complète du projet
Superviseur du corps professoral :

Tsun-Kong Sham

Étudiant :

Partenaire :

Springpower International Inc

Discipline :

Engineering

Secteur :

Professional, scientific and technical services

Université :

Western University

Programme :

Elevate

Multiple shock dependencies with applications to insurance risks

Traditional insurance models build on the assumption of independence of risks. One of the main causes of the recent financial crisis, this assumption has facilitated the quantification of risks for decades, but it has often lead to risks’ under-estimation and as a result under-pricing. Importantly, one of the prime pillars of the novel concept of Enterprise Risk Management is the requirement that insurance companies have a clear understanding of risks’ interconnections within the risk portfolios. However, modeling dependence is not an easy call. In fact, there is only one way to formulate independence, whereas the shapes of probabilistic dependence are infinite. In this project, we aim at developing tractable technically and interpretable practically probabilistic models of dependence that describe the adverse effects of multiple risk drivers on the risk portfolio of a generic insurer. The outcomes will be applied to the Own Risk and Solvency Assessment of Sun Life Financial.

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Superviseur du corps professoral :

Edward Furman

Étudiant :

Partenaire :

Sun Life Financial

Discipline :

Mathematics

Secteur :

Finance and Insurance; Commercial Services; Other

Université :

York University

Programme :

Elevate

Optical Fiber-Based Point of Care DNA Detection – Year Two

We aim to develop novel technologies for point of care DNA testing assisted by optical fiber devices. Specifically, the two main objectives are to achieve increased rapidity and improved multiplexing capabilities with respect to Spartan Bioscience’s current generation of products. This interdisciplinary project involves efforts in chemistry, biology, and photonics. On the photonics side, we must conceive an efficient and cost effective multipurpose fiber-based device and thoroughly optimize it, in addition to developing the optical setup to which it will be integrated. Following this research phase, significant engineering efforts will also be put into transferring this new technology from a laboratory setting to a product-like prototype. If the project is successful, the next generation of Spartan’s products will be based on these technologies and this will contribute to maintain Spartan as one of the world leaders in the new but highly competitive market of point of care DNA testing.

Voir la description complète du projet
Superviseur du corps professoral :

Jacques Albert

Étudiant :

Partenaire :

Spartan Bioscience Inc

Discipline :

Engineering

Secteur :

Manufacturing

Université :

Carleton University

Programme :

Elevate

Optical Fiber-Based Point of Care DNA Detection

We aim to develop novel technologies for point of care DNA testing assisted by optical fiber devices. Specifically, the two main objectives are to achieve increased rapidity and improved multiplexing capabilities with respect to Spartan Bioscience’s current generation of products. This interdisciplinary project involves efforts in chemistry, biology, and photonics. On the photonics side, we must conceive an efficient and cost effective multipurpose fiber-based device and thoroughly optimize it, in addition to developing the optical setup to which it will be integrated. Following this research phase, significant engineering efforts will also be put into transferring this new technology from a laboratory setting to a product-like prototype. If the project is successful, the next generation of Spartan’s products will be based on these technologies and this will contribute to maintain Spartan as one of the world leaders in the new but highly competitive market of point of care DNA testing.

Voir la description complète du projet
Superviseur du corps professoral :

Jacques Albert

Étudiant :

Partenaire :

Spartan Bioscience Inc

Discipline :

Engineering

Secteur :

Manufacturing

Université :

Carleton University

Programme :

Elevate

Biomechanical and metabolic analysis of world-class short-trackspeed skaters

Short-track speed-skating has been one of the most important medal-provider sport for Canada at Olympic Games for many years. However, research on performance determinants is very scarce, and Canada is progressively loosing ground compared to new countries interested in the medal potential of this sport. There is an urgent need to better understand the biomechanical and physiological constraints of this sport to enhance training effectiveness and performance. Using portable, cuttingedge technology, this research will create and validate a sport-specific set of biomechanical and physiological data for every athlete that will be used to optimise training load, inform athletes’ fatigue level, training adaptations, and potential injury risk. This research will foster technological development and individualize training interventions to give a wining edge to our male and female Canadian speed skaters.

Voir la description complète du projet
Superviseur du corps professoral :

François Billaut

Étudiant :

Partenaire :

Own the Podium (AB);Speed Skating Canada

Discipline :

Engineering

Secteur :

Technology; Health and Related Sciences & Technology; Other

Université :

Université Laval

Programme :

Accelerate

Rechargeable Hybrid Aqueous Gel Batteries for Start-Stop Applications in Automobile Vehicles – Year Two

Currently, all types of vehicles utilize a 12 volt lead-acid battery for start-stop, controls, comfort features, redundancy, and safety features. We aim to replace it by introducing a new rechargeable hybrid aqueous battery, which is lead-free and possesses more than twofold higher energy storage capacity. There are requirements to further improve the rate capability and to reduce water-loss of this battery. In this proposed research, we will use nanotechnology to re-design the cathode materials and electrode structures to improve the rate capability. We will design and fabricate new gel electrolytes which protect the water component from evaporation and thus enhance the battery’s service life. The collective advances attribute to this new battery and make it practical for use as the power source for the electrical system in vehicles. The research knowledge will contribute to the scale-up projects in POSITEC Canada Ltd., a company based in Toronto.

Voir la description complète du projet
Superviseur du corps professoral :

Pu Chen

Étudiant :

Partenaire :

Positec Canada Ltd

Discipline :

Engineering

Secteur :

Manufacturing; Professional, scientific and technical services

Université :

University of Waterloo

Programme :

Elevate

Rechargeable Hybrid Aqueous Gel Batteries for Start-Stop Applications in Automobile Vehicles

Currently, all types of vehicles utilize a 12 volt lead-acid battery for start-stop, controls, comfort features, redundancy, and safety features. We aim to replace it by introducing a new rechargeable hybrid aqueous battery, which is lead-free and possesses more than twofold higher energy storage capacity. There are requirements to further improve the rate capability and to reduce water-loss of this battery. In this proposed research, we will use nanotechnology to re-design the cathode materials and electrode structures to improve the rate capability. We will design and fabricate new gel electrolytes which protect the water component from evaporation and thus enhance the battery’s service life. The collective advances attribute to this new battery and make it practical for use as the power source for the electrical system in vehicles. The research knowledge will contribute to the scale-up projects in POSITEC Canada Ltd., a company based in Toronto.

Voir la description complète du projet
Superviseur du corps professoral :

Pu Chen

Étudiant :

Partenaire :

Positec Canada Ltd

Discipline :

Engineering

Secteur :

Manufacturing; Professional, scientific and technical services

Université :

University of Waterloo

Programme :

Elevate

Integrated hydrodynamic and water quality modelling tool for the Toronto Waterfront – Year Two

The goal of this project is to develop the first ever high definition integrated water circulation and water quality model for the Toronto Waterfront. As one of the most urbanized freshwater ecosystems with complex geometries and physical processes, Toronto Waterfront is in an urgent need for modern scientific tools that can support effective environmental management strategies and inform design of costly new development and restoration projects that have considerable socioeconomic implications. Additionally, this cutting edge integrated model will be used in collaboration with Toronto and Region Conservation Authority and key partners to study the impact of various scenarios of proposed urbanization developments on the water circulation, water quality and fish habitat in the Toronto Waterfront. The results from this research, such as the analysis of restoration strategies and predictions for the outcome of future developments, will ensure cost effective, sustainable investments while aligning with water quality provincial standards.

Voir la description complète du projet
Superviseur du corps professoral :

Mathew Wells

Étudiant :

Partenaire :

Toronto and Region Conservation Authority (Vaughan, ON)

Discipline :

Physics

Secteur :

Professional, scientific and technical services; Public administration

Université :

University of Toronto Scarborough

Programme :

Elevate

Integrated hydrodynamic and water quality modelling tool for the Toronto Waterfront

The goal of this project is to develop the first ever high definition integrated water circulation and water quality model for the Toronto Waterfront. As one of the most urbanized freshwater ecosystems with complex geometries and physical processes, Toronto Waterfront is in an urgent need for modern scientific tools that can support effective environmental management strategies and inform design of costly new development and restoration projects that have considerable socioeconomic implications. Additionally, this cutting edge integrated model will be used in collaboration with Toronto and Region Conservation Authority and key partners to study the impact of various scenarios of proposed urbanization developments on the water circulation, water quality and fish habitat in the Toronto Waterfront. The results from this research, such as the analysis of restoration strategies and predictions for the outcome of future developments, will ensure cost effective, sustainable investments while aligning with water quality provincial standards.

Voir la description complète du projet
Superviseur du corps professoral :

Mathew Wells

Étudiant :

Partenaire :

Toronto and Region Conservation Authority (Vaughan, ON)

Discipline :

Physics

Secteur :

Professional, scientific and technical services; Public administration

Université :

University of Toronto Scarborough

Programme :

Elevate

Chromosome Engineering for Bioproducts from Methanotrophs – Year Two

Currently Metagenom Bio Inc. offers contract research services in environmental microbial species profiling. Applications for this service include the monitoring of biogas operations, greenhouses, and mining processes. Metagenom Bio wishes to offer solutions that use microbes to generate value-added products. Biogas reactors can break down waste products and produce methane, or natural gas. This methane can be burned, or some of it may be used to create materials using bacteria that can consume methane. These bacteria are the methanotrophs, and some of them are able to make polymers that can be used as bioplastics. These bioplastics are biodegradable, biocompatible, and they are suited for use in medical applications and food packaging applications among others. We plan to use genome engineering methods to engineer methanotrophs so that we can use them to create a range of bioplastics for various industrial applications requiring desired physical properties.

Voir la description complète du projet
Superviseur du corps professoral :

Andrew Doxey

Étudiant :

Partenaire :

Metagenom

Discipline :

Life Sciences

Secteur :

Biotechnology; Clean Technology; Agriculture and Food

Université :

University of Waterloo

Programme :

Elevate

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