Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

29 670 projets achevés

2811
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4990
C.-B.
801
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663
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825
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8841
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9197
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95
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568
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1088
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Projets par catégorie

Antineoplastic evaluation of novel 3,5-bis(benzylidene)-4-piperidones

The principal objective of this proposal is to discover novel drugs to treat colon cancers. Currently colon cancer is a huge medical problem and there are many disadvantages to current drug therapies. These disadvantages include their ineffectiveness to completely eradicate cancers, causing toxic side effects and the development of multidrug resistance. A group of compounds discovered in the laboratory of the supervisor designated series 2 has significant potencies towards a number of human colon cancer cell lines. However it is unlikely that they will be effective when given orally due to their low water solubility. Thus this proposal outlines the preparation of analogs of series 2 which retain their anticancer properties but have increased water solubility thereby enabling the compounds to be given by mouth. Bertech requires novel anticancer agents in order to attach antibodies to them which are specific for colon cancers. In other words, this application is part of a long term strategy of Bertech to provide therapeutics and diagnostics for patients with colon cancer

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Superviseur du corps professoral :

J. R. Dimmock

Étudiant :

Partenaire :

Bertech Pharma Ltd

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Saskatchewan

Programme :

Accelerate

Data collection and cross-domain representation models for trajectory analysis

Due to the vast amount of available tracking sensors in recent years, high-frequency and high-volume streams of data are generated every day. Such tracking sensors include but are not limited to vessel, airplane or vehicle tracking data, drones, smartwatches and smart bands as well as cameras and earth observation sensors. Despite the overabundance of data generated by the tracking devices, there are still cases in which the trajectory of a moving object (e.g., vessel or human) has gaps, errors, or is unavailable. This research proposal aims to advance trajectory mining from a multimodal perspective, addressing challenges that might arise from single- or multi-source tracking data, across two main aspects: i) Data collection and creation: effort will be allocated to create open-access datasets from multiple data sources, acting as a basis for multi-sensor trajectory mining research. ii) Cross-domain representation models for trajectories: Transformation techniques are necessary to convert raw data into formats suitable for Artificial Intelligence/Machine Learning (AI/ML) applications. Hence, graph-based representation models inspired by other domains within the Information and Communication Technology (ICT) will be applied for trajectory analysis.

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Superviseur du corps professoral :

Aris Leivadeas

Étudiant :

Partenaire :

National Technical University of Athens

Discipline :

Computer science

Secteur :

Artificial Intelligence; Information and Communications Technology; Transportation (excluding aerospace)

Université :

École de technologie supérieure

Programme :

Globalink Research Award

Developing new soil-based methods for identifying blackleg disease causing fungal strains in canola crops.

Agricultural crop losses from fungal pathogens such as blackleg (Leptospheria maculans), a major disease of Canola, results in millions of dollars of economic losses each year. The rapid and conclusive identification of the presence of a fungal crop pathogen in a field before planting can help producers make informed decisions about crop selection. This project, undertaken with Whit Otter Inc. proprietary technology, will develop a method for the rapid and conclusive detection of fungal pathogens in a soil sample. The proof-of-concept study outlined here will focus on identifying strains of blackleg fungus in both test and field collected soil samples. This project will set the foundation for an expansion of the services that White Otter Inc. offers to include testing of agricultural samples for the presence of a wide array of pathogens.

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Superviseur du corps professoral :

John Sorensen

Étudiant :

Partenaire :

White Otter Biotech

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

University of Manitoba

Programme :

Accelerate

Étude de plasmas à onde de surface par spectroscopie d’émission

Le projet de recherche de Téo Clergereaux dans le groupe du Pr Luc Stafford au département de physique de l’université de Montréal vise à étudier le fonctionnement d’un plasma lors d’une injection pulsée de gaz. Cette étude reposera sur des mesures de spectroscopie d’émission optiques temporelles.
Cette étude s’intègre dans un projet beaucoup plus large d’injection d’aérosol dans ces plasmas pour le dépôt de couches multifonctionnelles (projet RI-plasma du Pr. Luc Stafford). L’utilisation des procédés assistés par aérosol ouvre de nombreuses applications par exemple dans le domaine de l’aéronautique ou de l’aérospatiale. Ils conjuguent physique et chimie des plasmas, nanosciences et nanotechnologies, ainsi que matériaux et procédés de fabrication durables, étudiées par exemple dans la Chaire de recherche du Canada en physique des plasmas hautement réactifs.

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Superviseur du corps professoral :

Luc Stafford

Étudiant :

Partenaire :

Université de Toulouse

Discipline :

Physics

Secteur :

Education

Université :

Université de Montréal

Programme :

Globalink Research Award

Use of platinum nanoparticles to enhance the sensitivity of microfluidic diagnostic tests

Rapid diagnostic tests play a crucial role in preventative medicine and epidemiology. Despite their widespread adoption in the industry, obtaining precise, quantitative results for low concentrations of analyte remains a significant challenge. For example, point-of-care (POC) tests for COVID-19 can exhibit a 70% rate of false negatives in some cases. The aim of this project is to combine the precise fluid control at small sample volumes of a microfluidic platform with the sensitive detection potential of platinum nanocatalysts (PtNCs). Indeed, these nanocatalysts, consisting of a gold core surrounded by a platinum layer, developed in Molly Stevens’ research group at Oxford, catalyze a reaction that continuously forms a coloured precipitate. This allows for signal amplification at unprecedented levels. The project aims to further a three-year long collaboration between Prof. Thomas Gervais at Polytechnique Montreal, and Prof. Stevens, by combining their expertise in Microfluidics and Nanoparticles to transform diagnostics.

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Superviseur du corps professoral :

Thomas Gervais

Étudiant :

Partenaire :

University of Oxford

Discipline :

Engineering

Secteur :

Biotechnology; Health and Related Sciences & Technology; Nanotechnology

Université :

Polytechnique Montréal

Programme :

Globalink Research Award

Machine Learning Developer intern working within cross-functional teams to develop and commercialize AI-powered solutions in the Financial Services sector (1)

“THIS IS A GENERIC TEXT PUT IN PLACE AS THERE WAS NO PROJECT OVERVIEW”

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Superviseur du corps professoral :

Svetlana Yanushkevich

Étudiant :

Partenaire :

AltaML

Discipline :

Computer science

Secteur :

Information and cultural industries; Professional, scientific and technical services

Université :

University of Calgary

Programme :

Business Strategy Internship

Dietary protein impact on post-prandial hepatic metabolic fluxes.

Obesity and type 2 diabetes (T2D) affect millions of people worldwide. When considering dietary strategies to offset T2D, the focus has been mainly to reduce amounts and specific types of fat and carbohydrates, with very little consideration given to protein sources. Earlier studies done by the applicant and colleagues showed that dietary protein composition influences inflammation and insulin resistance in both rodent models of obesity and in overweight people. These studies put forward the concept that dietary proteins modulate features of the metabolic syndrome. Subsequent work exploring the role of dietary proteins in the context of metabolic diseases have mostly focused on the quantity rather than focusing on the composition of protein sources. This is problematic since it is not representative of usual dietary protein intake, which ranges between 15-18% of daily energy intake. Studying metabolic alteration caused by different dietary protein sources is however challenging, due to the complexity of capturing post-prandial changes on metabolism, that are often transitory, but that could underlie long term impact on obesity and insulin resistance. This collaboration will bridge foreign expertise in metabolic fluxes techniques with our home expertise in dietary protein impact on metabolic health.

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Superviseur du corps professoral :

André Marette

Étudiant :

Partenaire :

University of Texas Southwestern Medical Center

Discipline :

Life Sciences

Secteur :

Health and Related Sciences & Technology

Université :

Université Laval

Programme :

Globalink Research Award

Calgary’s water main asset management using predictive models

All water utilities, engineering consulting firms, and provincial and federal departments in Canada responsible for design, operation, maintenance, rehabilitation, and development of a water distribution system would directly benefit from the outcomes of the proposed research. Efficient and effective asset management of water distribution infrastructure is a demand driven issue for any water utilities due to resources and budget constraints. The proposed research is targeting any water utilities under a good notion to improve asset management practices in Canada. Hence, City of Calgary’s water utility will be the first to benefit from the proposed research. The proposed asset management models can be adapted to other countries facing similar challenges. This research will help City of Calgary in specific and Canada in general to lead R&D in this domain. This research will train and prepare many high quality personnel’s that will be able to disseminate the knowledge in a near future.

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Superviseur du corps professoral :

Solomon Tesfamariam

Étudiant :

Partenaire :

City of Calgary;Russell NDE Systems Inc

Discipline :

Engineering

Secteur :

Public administration; Utilities

Université :

University of British Columbia - Okanagan

Programme :

Accelerate

Production of cellulose-based membranes with nanoadditions for air filtration

Global warming is one of the most pressing challenges of our time. Greenhouse gases like carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) trap heat, causing the planet’s temperatures to rise. Currently, the challenge is to achieve systems that solve problems such as environmental pollution through the design of green products and sustainable processes. Membranes are a selective barrier that allows certain species (molecules and ions) to pass through while blocking others. Cellulose-based membranes have been briefly studied as gas separation membranes to mitigate greenhouse gas emissions. So far, various membrane production methods have been reported, with the phase inversion being the most versatile technique. The aim of the present work is to develop membranes for high separation performance towards pollutant gases (e.g., CO2). The membranes will be fabricated using cellulose-derived materials (e.g., CA) through phase inversion. The addition of nanomaterials (e.g., nanocellulose) will be explored with the intention to achieve desired structural and chemical properties. This approach aims to optimize membrane selectivity, permeability, and stability by exploring the influence of different nanomaterials and fabrication parameters. The project will contribute to advancing sustainable and high-efficiency gas separation technologies, addressing critical challenges in environmental remediation and industrial applications.

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Superviseur du corps professoral :

Flavia Braghiroli

Étudiant :

Partenaire :

Universidade Federal Fluminense

Discipline :

Physics

Secteur :

Education

Université :

Université du Québec en Abitibi-Témiscamingue

Programme :

Globalink Research Award

Étude stylistique et des techniques de production du verre mosaïqué en Grèce à l’époque hellénistique

Le projet s’inscrit dans le cadre de ma maitrise sur l’étude du verre mosaïqué de l’époque hellénistique et sera effectué en deux parties. La première est de visiter des musée qui exposent de la vaisselle en verre et des sites archéologique qui ont produit du verre. Ceci sera une collecte de données essentiel à la continuation de mon projet de maitrise afin d’avoir un contacte directe avec mon domaine d’étude et d’analyser les détails difficiles à voir par photo. Certains objets sont aussi uniquement disponible en personne. La deuxième partie du projet est de participer aux fouilles d’Argilos où je contribuerai au travail de chantier, au nettoyage des trouvailles et le catalogage de ces objets. Pendant mon séjour à Argilos, je visiterai également des musée est des sites archéologiques de la région.
De retour à Montréal je ferrai l’analyse stylistique et des techniques des objets en verre mosaïqué que j’aurai vu et photographié dans les musées et je ferrai un travail de catalogage.

Voir la description complète du projet
Superviseur du corps professoral :

Jacques Perreault

Étudiant :

Partenaire :

Université de Patras

Discipline :

Sociology

Secteur :

Education

Université :

Université de Montréal

Programme :

Globalink Research Award

Metabolic control of reproductive maturation

There is a critical period during late gestation in humans and perinatally in atricial animals like rats and mice , during which the building blocks of energy homeostasis, including the hypothalamic regulation of food intake and energy balance become established. During this early postnatal period, neuronal dendritic and axonal elongation as well as pruning takes place, creating the circuits involved in the control of metabolism and reproduction. The proposed project will study how early life alterations of metabolic status affect the developmental trajectories of hypothalamic neurons resulting in alterations of the timing of puberty and increased susceptibility to metabolic disease and Polycystic Ovary Syndrome (PCOS) during puberty and adulthood. This is part of an ongoing international collaboration between Dr Lomniczi’s lab (in Halifax) and Drs Solari and Peluffo in Buenos Aires, Argentina. The participating institutions will benefit of reinforcing collaboration by the exchange of students, accelerating the discovery process as well as enhancing recruitment of students to our Graduate Programs.

Voir la description complète du projet
Superviseur du corps professoral :

Alejandro Lomniczi

Étudiant :

Partenaire :

Universidad de Buenos Aires

Discipline :

Life Sciences

Secteur :

Health and Related Sciences & Technology

Université :

Dalhousie University

Programme :

Globalink Research Award

Investigating pulse architecture for two-photon microscopy to improve capture of neural signals

Two-photon microscopy is a powerful imaging technique that allows to visualize and study living cells in the brain, immune system, and skin. It currently relies on lasers that emit specific pulse durations, but other pulse configurations may work just as well or better, and can be produced with smaller, more affordable lasers. This could make two-photon microscopy more accessible, especially for medical and clinical research.
This study aims to compare the current laser pulse settings with alternative configurations to see if they deliver similar or better imaging results. To do this, we will use two-photon microscopy to capture neural signals from the retina and brain of live mice, testing different pulse settings to assess their impact on image quality and neural activity.
The project is a collaboration between the Krishnaswamy Lab at McGill University and MPB Communications. MPB will design and build three lasers with varying pulse characteristics, which will be integrated into the Krishnaswamy lab’s microscope. The research will analyze neural data and image quality across these different pulse settings to determine the optimal configuration.
This study could lead to more cost-effective and efficient methods for two-photon imaging, benefiting both basic science and clinical research.

Voir la description complète du projet
Superviseur du corps professoral :

Arjun Krishnaswamy

Étudiant :

Partenaire :

MPB Communications (Pointe-Claire, QC)

Discipline :

Life Sciences

Secteur :

Information and cultural industries; Manufacturing

Université :

McGill University

Programme :

Accelerate

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