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We propose to develop a microfluidic device that enables the selection of viable sperm directly from semen via a simple dip approach. The device will feature a chamber incorporating a porous membrane. The sperm selection method involves only two steps – users load the device with a semen sample and place the device in buffer. Motile sperm are selected as they migrate out from the device via the pores to the buffer. This approach enables the selection of viable sperm and provides a user-friendly operation that fits seamlessly within the clinical workflow. The proposed project will modernize and advance the technologies used for sperm selection in assisted reproduction.
David Sinton
FlowLabs
Engineering
Health and Related Sciences & Technology
University of Toronto
Elevate
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Mitacs is funded by the Government of Canada, the Government of Alberta, the Government of British Columbia, Research Manitoba, the Government of New Brunswick, the Government of Newfoundland and Labrador, the Government of Nova Scotia, the Government of Ontario, Innovation PEI, the Government of Quebec, the Government of Saskatchewan, and the Government of Yukon.