Digital In-Line Holographic Microscopy in the Biological and Medical Sciences

Point Source Digital In-line Holography has been developed by Kreuzer, Jericho and

collaborators over the past fifteen years into an efficient and versatile microscopy that

produces 3-D images at the submicron level and can track the motion of objects like algae,

bacteria, bubbles and sand grains ocean and freshwater environments in real time, hence the

nomenclature 4D microscopy. Resolution Optics currently has three versions of DIHM

systems; the desktop model, the optical microscope attachment, and the self contained,

submersible model. Recent uses have been the (successful) search for algae and bacteria in

cold water springs in the high Arctic [7], in coastal waters of Nova Scotia and in a survey of

phytoplankton at depths down to 6000m in the mid Atlantic. The objective of the research

project is to develop new applications and uses of DIHM in biological and medical imaging is

to develop protocols that allow stable long term imaging over days and months to follow the…

Faculty Supervisor:

Laurent Kreplak

Student:

Partner:

Resolution Optics Inc

Discipline:

Physics

Sector:

University:

Dalhousie University

Program:

Accelerate

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