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In vitro degradation of polymeric drug carrier for sustained release of therapeutics
The focus of this study is on the understanding of degradation rate and mechanism of the polymeric drug carrier for intra-articular injection of therapeutics. For this aim a radical-containing and enzyme-containing medium will be used to accelerate the degradation conditions. At each time point the mass loss and Tg of the hydrogels will be calculated and the structure and molecular weight of the degradation products will be characterized. The potential degradation mechanism will be proposed for the polymers.
Faculty Supervisor:
Brian Amsden
Student:
Partner:
Eupraxia Pharmaceuticals
Discipline:
Engineering
Sector:
Manufacturing
University:
Queen's University
Program:
Accelerate
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