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Metabolic Engineering of Retinoid and Phytoene Synthesis Pathway in E. coli.
Phytoene is a colorless carotenoid that absorbs light in UVA(286nm). It has powerful antioxidant and UV blocking effect and is used as a useful cosmetic material that can cope with the urban aging of skin in modern people. The purpose of this study is to construct and optimize phytoene biosynthetic pathway using E. coli. To make a microbial cell factory which is capable of mass production of phytoene in E. coli, redesign and optimze the core metabolic pathways that efficiently support it.
Faculty Supervisor:
Dae-Kyun Ro
Student:
Partner:
Gyeongsang National University
Discipline:
Life Sciences
Sector:
Biotechnology; Life Sciences (not health)
University:
University of Calgary
Program:
Globalink Research Award
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Mitacs is funded by the Government of Canada, the Government of Alberta, the Government of British Columbia, Research Manitoba, the Government of New Brunswick, the Government of Newfoundland and Labrador, the Government of Nova Scotia, the Government of Ontario, Innovation PEI, the Government of Quebec, the Government of Saskatchewan, and the Government of Yukon.