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Online monitoring and optimization of a reactive crystallization process
This project aims to experimentally investigate the optimal operating conditions for the reactive crystallization of compounds. A stirred-tank reactor will be set-up and the effects of mixing conditions on the resulting crystal particle size distribution will be investigated. Techniques for the online monitoring the reaction process will be explored, which will be used for model predictive control. This is an important process in pharmaceutical manufacturing as many drug products must be produced as a crystal with well-defined size distribution.
Faculty Supervisor:
Li Xi
Student:
Partner:
Nagoya Institute of Technology
Discipline:
Engineering
Sector:
Education
University:
McMaster University
Program:
Globalink Research Award
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