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Scalability Development of Fc3TSR Preparation Using Shake Flasks and Bioreactors
This project will help improve the way a promising new cancer treatment protein, called Fc3TSR, is made in the lab. Fc3TSR has shown the ability to shrink tumors by changing how blood vessels grow in cancer, making treatments like chemotherapy more effective. However, making enough of this protein for further testing and future use is a big challenge. In this project, university researchers and industry partners will work together to find better ways to produce and purify Fc3TSR using specialized cells and bioreactors. The intern(s) will test different production conditions and help develop a method that can be scaled up safely and efficiently. This work will benefit the partner organization by speeding up the path to clinical trials and future commercialization, helping bring a new cancer therapy closer to patients.
Faculty Supervisor:
Fei Geng
Student:
Partner:
Novel Oncology Research and Innovation Inc.
Discipline:
Engineering
Sector:
Professional, scientific and technical services
University:
McMaster University
Program:
Accelerate
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Mitacs is funded by the Government of Canada, the Government of Alberta, the Government of British Columbia, Research Manitoba, the Government of New Brunswick, the Government of Newfoundland and Labrador, the Government of Nova Scotia, the Government of Ontario, Innovation PEI, the Government of Quebec, the Government of Saskatchewan, and the Government of Yukon.