siRNA Therapy of Blood Cancer – Preclinical Efficacy & Safety Evaluation

Nucleic acids such as DNA and RNA offer exceptional opportunities to fight against infectious and genetic diseases. To use nucleic acids effectively in a clinical setting, one needs to use effective delivery vehicles that can deliver the nucleic acids into the diseased cells. This project will develop effective delivery systems for this purpose. The delivery systems will be used to deliver RNA based therapeutic agents in particular diseases, namely hematological cancers. We will develop specific drugs against these diseases and test them in animal models of the diseases. Successful completion of this project will advance the therapies towards clinical testing.

Faculty Supervisor:

Hasan Uludag

Student:

Partner:

RJH Biosciences Inc.

Discipline:

Engineering

Sector:

Biotechnology; Biomanufacturing; Nanotechnology

University:

University of Alberta

Program: