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Validation of a novel ionizable lipid library
Tiny particles made of fat are an established system for delivering genetic materials into cells to perform gene therapy. The project is focused on optimizing the fat structure and composition to improve genetic material delivery and target to different parts of the body. We will engineer a library of fat particles made with different combinations of fats. We will study their gene delivery efficiency in small animals. Results from this research will help us develop a better delivery system for genetic materials for improved gene therapy for many diseases.
Faculty Supervisor:
Shyh-Dar Li
Student:
Partner:
Dionamix Scientific Inc.
Discipline:
Life Sciences
Sector:
Manufacturing; Professional, scientific and technical services
University:
The University of British Columbia
Program:
Accelerate
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Mitacs is funded by the Government of Canada, the Government of Alberta, the Government of British Columbia, Research Manitoba, the Government of New Brunswick, the Government of Newfoundland and Labrador, the Government of Nova Scotia, the Government of Ontario, Innovation PEI, the Government of Quebec, the Government of Saskatchewan, and the Government of Yukon.