A mass spectrometry approach to unveil cytoplasmic bacteria interactomes

The innate immune system is the first line of defense of our body against pathogenic bacteria. It uses a sophisticated arsenal of proteins that recognize and fight infection. Certain bacteria, like the food-borne pathogen Salmonella, can enter cells in your body to hide. We recently identified novel immune sensors that allow the recognition of these […]

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Maternal disability and newborn discharge to child protective services (CPS): A mixed-methods study

As many as one in 8 pregnancies are to women with disabilities, including physical, sensory, and developmental disabilities. These women often face negative attitudes and assumptions by others about their parenting abilities and are at risk of Child Protective Service (CPS) involvement. This project aims to characterize CPS involvement experienced by women with disabilities in […]

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Nanomaterial interactions with soil microbial communities and soil fauna

Conventional agriculture needs large inputs of nutrients, through the addition of fertiliser, in order to produce the amount of food needed globally to sustain the population. Typical fertilisers are hugely wasteful, polluting the atmosphere and waterways, and affecting human health, wildlife, and ecosystem stability. Nanomaterials are very small particles that have potential to be used […]

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Investigating Sex Differences in Beta Cell Calcium Handling

Diabetes is a disease affecting around 10% of the population which is caused by an inability to regulate blood glucose levels. Sex differences exist in diabetes; men have increased incidence of type 2 diabetes compared to pre- menopausal women. Blood glucose levels are normally tightly controlled by insulin release from beta cells in the pancreas, […]

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Modeling Protein-Ligand Cryo-EM Structures with Neural Network Potentials

Drugs act by binding to a target protein. Determining the three-dimensional shape the complex between a drug and a protein is challenging, particularly when the protein spans the membrane separating the interior and exterior of a cell. Cryo-electron microscopy allows these structures to be measured experimentally, but often the resolution is too low to aid […]

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Developing a robust approach to the monitoring and analysis of insect populations: trends in fly numbers in Québec and implications for insectivores

Insects, being dominant in almost all ecosystems, are vitally important for regulating ecosystem health. There are growing concerns that insect abundance is declining globally, causing serious consequences for ecosystem services. To understand insect abundance trends, and their drivers, we need long-term monitoring schemes that are sensitive enough to detect change over time whilst balancing against […]

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Validating a drug resistance marker for a globally important ruminant parasite

The barber-pole worm (Haemonchus contortus) is a parasitic worm of sheep, goats and cattle common in both UK and Canada. Infection of the barber-worm causes reduction in animal growth and milk production in addition to general poor health and high risk of death, costing millions from production losses annually in Canada and the UK. Symptoms […]

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Le marquage CE sous la nouvelle réglementation Européenne 2017/745 – Le cas d’une compagnie canadienne

Le stage en stratégie d’entreprise Mitacs que j’effectue pendant huit mois consistera en développement des dossiers techniques dont celui pour le marquage CE (« conformité européenne ») sous la nouvelle réglementation Européenne 2017/745. Dans le cadre du stage, j’aurai comme responsabilités d’établir et exécuter une stratégie réglementaires pour les portions du projet qui me seront […]

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Intégration des connaissances sur les habitats fauniques pour la planification territoriale autochtone : le cas du lynx du Canada

Le projet vise à caractériser le potentiel d’habitat de plusieurs espèces culturellement significatives, dont le lynx du Canada, sur le territoire de 2 communautés autochtones de l’Abitibi, à proposer un zonage du territoire selon des vocations identifiées par les communautés (ex. chasse au petit gibier) et à élaborer des recommandations d’aménagement du territoire. Le stagiaire […]

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Optimizing online therapy with cognitive rehabilitation

Executive functions are a collection of higher-level cognitive abilities that support decision making, planning, attentional focus, and error correction. Mental slowing, inefficiency, and feeling blue are – to some degree – expected with any serious illness. Goal Management TrainingTM (GMT) is a made-in-Ontario healthcare innovation, developed by researchers at Baycrest, a Toronto-based academic health science […]

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