Budget Impact Analysis guidelines for submissions to provincial drug plans in Canada (Update 2018- 2019)

In the health technology assessment (HTA) process, cost- effectiveness analysis gets more attention, however over last decade, the budget impact analysis (BIA) has certainly become more important to the subsequent steps, including the adoption decision. The first Canadian BIA Guidelines was published by Patented Medicine Prices Review Board (PMPRB) in 2007. According to the results […]

Read More
Development of the Community Paramedicine Contact Assessment

In the absence of a standardized approach to patient assessment in community paramedicine programs, it is difficult to determine if these programs are helping patients when comparing one to another. Governments across Canada have invested in community paramedicine as an approach to provide care for patients in their homes rather than transporting them to the […]

Read More
Portfolio Strategies under Scenario Optimization

This project concentrates on the scenario optimization method which does not need to make any assumption for the underlying asset distribution and directly incorporate such uncertainty into the objective or constraint functions through stochastic programming. The scenario optimization is performed under different parameters and constraints while Markowitz and Black-Litterman model are taken as the benchmarks […]

Read More
EEG Signal Processing as a Predictor of Anti-Depressant Response

Major depressive disorder (MDD) is a serious mental condition that often completely debilitates a client. MDD is typically treated with one of several currently available antidepressant medications. However, the response rate to any of these medications is only about 30%. Unfortunately, there are currently no means for a priori assessment of whether a specific person […]

Read More
Universal surface modification method to encourage cell patterning

Surface modification to promote the patterning of mammalian cells is an important tool in cellular biology. It aids in the development of different tissue engineering scaffolds, biosensors, and validation of high throughput screening assays. Surface modification protocols must be tailored to each individual material which limits the utility of a successful antifouling strategy to individual […]

Read More
The role of serpin-producing B. longum as an inhibitor of gluten/ATI-related innate immuneactivation

Gluten-related disorders include a variety of clinical entities triggered by the ingestion of gluten containing cereals. The best characterized condition is celiac disease, an autoimmune enteropathy occurring in genetically susceptible individuals. Non-celiac gluten sensitivity or non-coeliac wheat sensitivity (NCGS/ NCWS) is a clinical descriptor of patients, in whom celiac disease and wheat allergy have been […]

Read More
Probiotic modulation of mast cells

Probiotics are bacteria that provide health benefits when eaten. However it is difficult to identify which bacteria may have beneficial properties and therefore identification of new probiotics is a time consuming and expensive process. In this project the intern will examine the effect of different potential probiotic bacteria on a specific cell type, the mast […]

Read More
E-Community Health and Toxicity

Online communities abound today, arising on social networking sites, on the websites of real-world communities like schools or clubs, on web discussion forums, on the discussion boards of videogames, and even on the comment pages of news sites and blogs. Some of these communities are “healthy” and foster polite discussion between respectful members, but others […]

Read More
Developing an On-field Test for Determining Recreational Water Quality

Recreational water sources are important commercial resources and activity hubs. Unfortunately, any public water source is prone to bacterial and viral contamination, which is a major concern for public health agencies. InnovoGENE Biosciences has a developed a simple test that can quickly determine the level of pathogens. Although this method has been rigorously tested in […]

Read More