Lowering Costs in Biotherapeutics: Raman Spectroscopy for Real-Time Antifoam Detection in Perfusion Bioreactors

This project aims to improve the production of monoclonal antibody (mAb) based medicines by developing a novel method for measuring antifoaming agents within perfusion bioreactors used to produce mAbs. Antifoams are necessary to keep bioreactors running smoothly, but they are also widely believed to contribute to reactor membrane fouling, which increases costs and severely limits […]

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L2M Launch – Commercialization of Natural Polymer-Based Wound Dressings

In collaboration with the Lab2Market Launch program, our goal is to transition our natural polymer-based wound dressing from the lab bench to commercial scale. Designed specifically for individuals with chronic wounds and fragile skin conditions, our hydrogel-based dressing aims to fill a critical gap in the market. Through the program, we seek to deepen our […]

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L2M Launch – Wonder Guard: An AI-Powered Catheter Sensor System to Detect and Predict Infection

Wonder Guard is an AI-powered catheter sensor system that is capable of detecting and predicting infection. We are developing an infection surveillance system using electrochemical DNA biosensors and AI-driven analytics to make assisted diagnoses. The device is a module add-on to existing hospital catheter systems that can continuously produce and analyze data to monitor UTIs, […]

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L2M – IUAide by ReFem Technologies

ReFem Technologies is developing IUAide, a new medical device that makes intrauterine device (IUD) insertion safer, faster, and less painful. The current procedure uses outdated tools that cause discomfort and inefficiency for both patients and clinicians. IUAide combines gentle stabilization, local anesthesia, and real-time placement feedback into one easy-to-use device. Through this project, ReFem will […]

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Laboratory-Based Transmission Electron Microscopy Technique to Study Electrochemical CO2 Conversion under Operating Conditions

The growing urgency to combat climate change has driven major interest in technologies that can capture and convert carbon dioxide (CO2) into useful fuels and chemicals. Electrochemical CO2 conversion is a focus area in carbon capture and utilization storage (CCUS) as a potential disruptive technology for a circular carbon economy, including decarbonization of chemical manufacturing, […]

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Advancing a Learning Health System for Mood Disorders

Many patients with mood disorders, which include major depression and bipolar disorder, continue to experience symptoms even after receiving treatment. Traditional research methods have helped improve care but often don’t reflect the realities of clinical practice, which slows progress in applying research to improve services. This project aims to support St. Joseph’s Healthcare Hamilton (SJHH) […]

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Design and Implementation of a Generalized, Secure, and Scalable API

DiamondAI and McMaster University are working together to create a secure and scalable software interface, called an API, that connects DiamondAI’s career guidance platform with the online systems used by schools and colleges. DiamondAI helps students and newcomers understand their strengths and interests through personalized assessments powered by artificial intelligence. Right now, most schools use […]

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L2M – Clean Hydrogen and Ocean Alkalinity Enhancement through Bipolar Membrane Electrodialysis

This project aims to advance a clean technology that uses an electrodialysis process to remove acidity from seawater while producing green hydrogen. Using seawater and renewable electricity, the system removes excess acidity, encouraging ocean carbon uptake. The result is de-acidified seawater capable of absorbing more carbon dioxide, while simultaneously producing green hydrogen as a valuable […]

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Improving the efficiency of identifying practice ready evidence and generating evidence summaries

EBSCO improves the dissemination of high-quality, clinically relevant content to healthcare providers through DynaMed, their online clinical textbook that is constantly being updated as new research is published. This process includes many experts and has many steps. McMaster University’s Health Information Research Unit’s (HiRU) literature surveillance program filters medical research studies and passes them to […]

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Advanced FLIM-Hyperspectral confocal microscopy

This project aims to develop a high-resolution and high-speed microscope for capturing fast cellular biological interactions and processes. CoVision, a custom microscope instrumentation company, will directly work with the research fellow to develop and build this custom system. This includes designing the commercial grade packaging, sourcing components, and development of the user interface to be […]

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Designing guar gum-based hydrogels for promoting anti-adhesion and anti-infective skin wound healing

Epidermolysis bullosa (EB) is a series of hereditary skin fragility conditions, currently without a cure, that are characterized by fragile skin that is prone blister formation in response to minor friction or trauma. Existing wound dressings are often too abrasive and/or stiff to effectively treat this condition without compromising healing, demanding new materials solutions to […]

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Electric Drive Systems for Automotive Propulsion Applications

Electrified vehicles (EV), which include hybrid, battery, plug-in, and fuel cell technologies, will be critical in helping lower emissions, reduce fossil fuel usage, and help mitigate climate change. The next generation of EVs will require significantly improved powertrains, components, and associated control technologies. The proposed project will research and develop components, architectures, and systems that […]

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