Our project aims to develop polymer-lipid hybrid nanoparticles (pLNPs) to enhance gene delivery to cells throughout the body, addressing two major challenges: ineffective release of genetic material inside cells and limited targeting of non-liver tissues. By incorporating a pH-sensitive material, our pLNPs are designed to improve the release of their genetic cargo within cells while […]

Despite the proliferation of mini forests across Canada, and the financial commitment to increase canopy cover in urban areas, there is very little systematic research conducted on the range of benefits and the effectiveness of mini forests. For the MITACS Accelerate we envision involving an undergraduate student as a project intern to support the development […]

Learning a motor task is dependent on many cortical regions. As a skill is learned, changes take place within the circuitry of the brain to optimize efficiency of the movement execution. Following stroke, motor deficits in the upper extremity are common, emphasizing the need for intact skill learning to reacquire motor function. Advancements in rehabilitation […]

The ongoing illicit drug poisoning crisis in Canada has resulted in over 40,000 deaths since 2016, with British Columbia being the province hardest hit. The crisis is largely driven by the presence of potent fentanyl analogues in unregulated drugs, leading to this significant rise in overdose deaths. In contrast, Europe, including France, has not experienced […]

Cardiac arrhythmia is an electrical disturbance in the heart which can cause a variety of potentially life threatening conditions. Arrhythmias are due to malfunctions in the protein channels, which in turn alter the bioelectric currents signaling each heartbeat. A key channel responsible for terminating the electrical signal is the voltage gated potassium channel, IKs. During […]

The proposed research explores how a virtual reality (VR) driving simulation can assess drivers’ ability to perceive hazards and how accurately it reflects their real-world driving experience. Participants from UBC will engage in a lab-based VR simulation where they will navigate various driving scenarios with the goal of identifying potential road hazards. Their performance will […]

This research project is focused on grizzly bear populations in southern British Columbia at the extent of their species range. While population recovery has occurred in parts of the ragnge, some popualtions continue to deline and large areas remain extirpated. Where the degree of population fragmentation is known this project will focus on analyzing how […]

Ce projet de recherche a pour objectif de créer une édition numérique des registres de comités de la Comédie-Française. Ces registres témoignent de la vie quotidienne de la troupe de théâtre, et sont actuellement conservés à la bibliothèque-musée de la Comédie-Française. Grâce au travail des étudiants et étudiantes de master sous la direction de Florence […]

This project is aimed to develop an inexpensive device for general public in monitoring skin healthcare condition. The device will be able to take magnified images of skin in order to observe more detailed skin conditions. A low cost version of the device will be able to attach to a smartphone and use the built-in […]

Using a verification-based approach for database storage backends has the potential to avoid such bugs, but specifying the complexity of a modern backend upfront is a daunting task. To decompose the problem into smaller pieces, we base our approach on the following insights: (1) There are two broad classes of backends: eager, state-based maps, vs. […]

This project aims to improve how lake ice is monitored in Canada by combining images from optical and RADARSAT-2 satellites with advanced data analysis techniques. Monitoring lake ice is important because it reflects climate changes, which affect both local and global environments. The partner company, ApoSys, specializes in using satellite technology for environmental monitoring, but […]

Le projet portera sur l’étude de l’impact de goutte de fluides complexe qui a de nombreuses applications industrielles ou en géophysique. Nous utiliserons notamment des fluides à seuils qui ont la particularité de se comporter comme des solides lorsqu’il sont faiblement sollicités et comme des fluides quand on a dépassé une contrainte limite dite contrainte […]