Chudnovsky-Ramanujan Type Formulae

In a well-known 1914 paper, Ramanujan gave a number of rapidly converging series for 1/pi which are derived using modular functions of higher level. The Chudnovskys derived an analogous series representation 1/pi, often used in practice for record breaking computations of pi. These formulae have recently been explained in the context of elliptic curves, modular […]

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Cellular regulation of human inducible nitric oxide synthase

The main aim of the project is to find new mechanisms by which Inducible nitric oxide synthase (iNOS) expression is regulated in human cells. Regulation of iNOS through post-translational mechanism stage can give better results. That is why in this project iNOS expression is controlled at the post-translational level. High concentration of NO can cause […]

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Position sensitive detector density well logging tool development

In well-logging industry, gamma-ray density logging is an indispensable method to determine formations’ lithology and porosity. This research proposal under the support of MITACS and Rimpac Advanced Technology Development Ltd. aims at developing a high-resolution density well logging tool which is expected to achieve higher precision and better vertical resolution of formation density measurement. This […]

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Molecular measures of yeast exhaustion in commercial brewing

Beer production is only as good as the yeast that make it. When yeast are first pitched for brewing, they produce the desired fermentation product—beer. But, after numerous cycles of fermentation, the yeast become exhausted and produce beer with unwanted flavors and alcohol content. As such, the beer is no longer fit for consumption. Over […]

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Characterizing dissolved methane in groundwater in the Peace Region, Northeast BC, using a regional, dedicated groundwater monitoring well network

The rapid increase in shale gas development in the Peace Region has been accompanied by concern about environmental impacts, and in particular, fugitive methane migration into shallow groundwater. The goal of the proposed research project is to establish a dedicated groundwater monitoring well network in order to collect data to inform the following questions: 1) […]

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A Snow Water Equivalence Estimation Prediction (SWEEP) System to Improve Hydrologic Forecasts in British Columbia

The mountains of British Columbia store vast, but varying, amounts of water in winter snowpacks. Accurate estimates of snow water equivalent (SWE) in these mountains are critical for hydroelectric power generation and flood forecasting, but the current observation network is often insufficient. Working with both industry and academic partners, Mitacs interns will use airborne laser […]

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Enhanced Model Suitability Analysis in Catastrophe Modelling through an Improved Understanding of the Seismic Hazard in Western Canada

One of the most destructive natural disasters that Canada could experience is a major earthquake affecting a highly-populated area. A 2013 study commissioned by the Insurance Bureau of Canada estimated that a magnitude 9.0 earthquake in British Columbia, and a magnitude 7.1 earthquake in the Quebec City-Montreal-Ottawa corridor would result in financial losses of almost […]

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Motion fields with deep reinforcement learning for real-time character animation

Character motion in games and animations often have high requirements of realism, aesthetics, and interactivity. For instance, in soccer simulation games, users control the players to move in different directions and perform actions such as passing and shooting. Modern data-driven approaches like motion fields provide convenient ways to synthesizing natural motions from a given database […]

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Business Models in Emerging Digital Platform Markets

The small business sector plays a critical role in stimulating economic development. In the last two decades, the Internet of Things (IoT) has attracted significant investments by diversifying entrant firms like Amazon and Netflix, and startups like Airbnb and Spotify to bundle resources, including generic technology and market assets from different markets, to design and […]

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Inter-Operability Standards in Information Technology Sector: The Role of Coopetition

1. development of a simulation mode of the information Technology Sector 2. Understanding and modelling the simultaneous Competition and Cooperation (“co-opetition”) among firms where they jointly form interoperability standards by consensus under the ambit of their chosen Standards Setting Organizations (SSOs). 3. Conduct Analysis using an appropriate simulation method, which will be implemented using either […]

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Design and optimization of new peroxidase ribozymes based on RNA Mango constructs

DNA and RNA oligonucleotides that fold to form four-stranded structures (G-quadruplexes) are known to bind heme and such complexes to catalyze 1-electron (peroxidase-like) and 2-electron (peroxygenase-like) oxidation reactions. While successful in competing with protein peroxidase enzymes in this respect, G-quadruplex•heme complexes are currently not competitive with protein enzymes with regard to the enantioselectivity of the […]

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Translational Research in User Experience Design for Personalized Health

Personalized health is increasingly gaining public attention in the media as the future of healthcare. Personalized health is the idea that medical treatment will be tailored to the individual based on their predicted response or risks of disease. Omics analysis, defined as the universal detection of different classes of biological molecules, has the potential to […]

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