Therapeutic efficacy of tryptamine analogues in a PC12 Cell as a model of depression via assessment of neurite outgrowth and enhanced cellular viability

There is a growing body of evidence that certain combinations of bioactives derived from natural source products may have potent effect on neuritogenesis and foster neuronal cell viability. The effect of neuron plasticity suggests there are potential treatments of major neurodegenerative and psychiatric conditions. In this project we are proposing to use a robust in […]

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Improving Estimates of Complex Option-BasedEmployee Compensation

Stock-based compensation allows employers and employees to share in the risks and rewards of their company’s success. In addition to intangible benefits such as team building and goal sharing, there can also be large financial rewards for employees and similar costs to employers. These costs must be reported in the company’s financial documents such as […]

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Expanding Web-Based Educational Opportunities for Canadian Students in STEM

The closure of schools across Canada during the COVID-19 pandemic has revealed significant gaps in educational provision. In addition, K-12 teachers have had difficulty finding learning resources related to the programs they are responsible for teaching. When students fall behind in school, they develop a learning gap with their peers. Learning gaps are relatively common […]

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Bioorthogonal spin labeling approaches for high sensitivity electron paramagnetic resonance spectroscopy – Part 2

In order to investigate proteins in their natural environment one can attach tiny reporter molecules to them that can be traced with appropriate instruments. However, these small reporter molecules may often cause strong perturbations to the functionality of the proteins, or cannot be seen due to experimental restrictions like low concentrations. Bioorthogonal chemistry aims to […]

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Application and optimization of molecular methods as an early predictor of cannabinoid content through the growing process of select cannabis cultivars in an industrial starter plant production

This project will allow Apollogreen and Loyalist College’s Applied Research Centre (ARC) to establish expertise based on a new analytical approach of cannabinoids at an early growth stage, allowing them to analyse and select cultivars to be commercially grown based on the sought after components for specific applications of licenced producers. This analytical process uses […]

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Development of a polishing treatment process (PTP) for anaerobic digester centrate

The production of biogas via the anaerobic digestion of organic waste is a growing industry in Canada. One benefit of this approach is that the resultant organic waste (digestate) can be dewatered and used as fertilizer; however, the removed water fraction remains rich in organic compounds and must be adequately treated before being discharged from […]

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Post COVID-19 Operational Transformation and Strategic Data Analysis

With the onset of COVID-19, the commercial real estate industry has been greatly impacted as fewer individuals and businesses are using office spaces. As such, with growing uncertainty, it is imperative to adapt, develop, and strategically plan for the foreseeable future. This project serves two purposes: 1) Assist in operational transformation using cloud-based technology and […]

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Measuring up? Assessing approaches used to measure the effectiveness of protected areas at conserving biodiversity

The world is currently facing a biodiversity crisis driven by the loss and degradation of habitat resulting from the conversion of natural areas to agricultural land and urban development. To combat this biodiversity crisis, the government committed to Convention of Biological Diversity and national targets of protecting at least 17% of terrestrial land through network […]

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Infrastructure Corrosion Assessment Magnetic Method (iCAMM) technology for macro and micro defect detection of rail track

Because of the usefulness of non-destructive testing in the assessment of different types of materials, they have attracted widespread interest in the last years. Non-destructive testing (NDT) is a descriptive term used for the examination of materials and components in such a way that allows materials to be examined without changing or destroying their function. […]

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Web Tools for Intelligent Real-Time Data Analy-sis

Data analysis plays an important role in healthcare as it enables service providers to discover hidden knowledge in the data, allowing them make more informed decisions about patients’ health. The continuing increase in the amount of data and lack of skilled people, however, has made data analysis very challenging. This project aims at developing web-based […]

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