Parkinson’s disease (PD) is the second most common neurodegenerative disease. PD is caused by genetic predispositions leading to neuronal cell death. Dysfunction of damaged mitochondrial turnover by mitophagy (mitochondrial autophagy) and the ubiquitin-proteasome system has been found in most cases of genetic PD. The ubiquitin-proteasome system mediates protein degradation trough ubiquitination – a post-translational modification […]

Using genome-wide data in collaboration with the Peruvian Genome Diversity Project, our goals are: (i)Populations from the Peruvian Central Andes are highly homogeneous. We use Approximate Bayesian Computation and patterns of identity-by-descent to infer when the intensification of the gene pool homogenization on this geographic region started, in the historical context of the Andean prehistory. […]

Precarious employment is an increasingly common term used to highlight labour market insecurity (McCann and FUDGE, 2017). In Canada, precarious employment usually relates to atypical forms of work that can present all or some of those characteristics: limited or no social benefits and statutory entitlements, insecurity and low paid, high safety or/and health risks (Vosko, […]

Binary fission, the process in which one bacterium divides into two identical cells, is the most common form of bacterial cell division. However, not all bacteria grow like this. The Streptomyces are a filamentous bacterium that undergo a lifecycle (similar to eukaryotic fungi) which culminates in sporulation. The Streptomyces are a biomedically important bacterium as […]

The project “Challenges and opportunities for conducting physical activity research in the Latin American context” consists of a capacity building experience, in which an international PhD candidate in Epidemiology, member of the Healthy Active Living and Obesity research group, will spend 4 months in a research internship that will allow her to be involved in […]

A new target on HIV gp120 for interventive drug therapy has been discovered and a company, ViroCarb, initiated to screen for small molecule inhibitors that bind in this site. Two structurally related inhibitors have been isolated from chemical libraries. This internship is to determine the scope of these inhibitors, whether they are able to inhibit […]

The design and operation of energy systems, specifically those driven by chemical processes such as gasification and coal combustion have long been associated with theoretical model-ling studies done within chemical engineering. However, with the rising need to face challenges brought upon by a warming climate and increased emissions from fossil fuel sources, there is significant […]

This project is designed to determine best management practices for a devastating disease of turfgrass that is currently controlled primarily by multiple fungicide applications. By assessing appropriate cultural practices aimed at reducing disease development it is our hope that we can reduce fungicide applications for this disease. In addition, the development of a rapid and […]

Energy-driven pattern formation induced by competing short and long range interaction in multi-species systems is pervasive in the natural world. The phenomenon of self-organization during pattern formation is quite common, and encountered in a variety of fields, such as biological systems like animal coats and skin pigmentation, and physics. As an example, we cite the […]

Agnico Eagle Mines Ltd. has proposed the Whale Tail Project, approximately 130km North of Baker Lake, NU. The project includes the construction a dyke within Whale Tail Lake that will divert water from the proposed mining pit into the surrounding lakes and tributaries, resulting in flooding that will elevate the water levels by 4 m […]

Spinal cord injuries and other pathologies of the spinal column represent a large cause of disabilities or deaths and significantly affect the quality of life of the individuals affected. To reduce the risk of further injury during spinal surgery and to support diagnostic and treatment, there is a need for a non-invasive real time monitoring […]

Synthetic chemistry is used to assemble the small organic molecules that comprise many of the important consumer products used by society every day. Such fine chemicals are used to assemble drugs, agrochemicals, electronics, materials, dyes, etc.. Metal catalysts are part of the arsenal that the synthetic chemist uses to make such prized small molecules and […]