Using high-throughput mapping techniques to reveal mechanisms of vocal learning

Understanding how humans and non-human animals communicate with each other continues to be a central question in neuroscience. Songbirds serve as powerful animal models for this endeavor because they learn their vocalizations (“songs”) in a manner that resembles how humans learn to speak and because vocal learning in songbirds is regulated by discrete brain circuits […]

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Improving the performance of manufacturing processes at GE Bromont by using artificial intelligence and pattern recognition

The products manufactured at GE Bromont go through a series of processes that produce the specific characteristics of each product according to required specifications. The number of these characteristics is very large, and several characteristics are dependent on the others. This reality makes the use of traditional statistical techniques for quality control of products laborious […]

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Identification of early markers of developmental epigenetic anomalies in bovine production

Bovine production uses a combination of Assisted Reproductive Techniques (ARTs) to improve yield and reduce generation time. In bovine production and in clinical settings, ARTs are associated with elevated rates of developmental disorders in offspring, leading to animal distress, high costs and delayed results. These include Large Offspring Syndrome (LOS) and musculoskeletal anomalies, reported to […]

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Stability of Protein-PEDOT:PSS Coating for Implantable Electrodes

Medical devices that are implanted into the human body allow for continuous medical monitoring and intervention, such as stimulation, recording, and drug delivery. Cardiac pacemakers and insulin pumps are examples of novel technology implanted for long-term treatment. For the treatment of neurological disorders, recent advances in neuroengineering consider the use of implantable electrodes. However, these […]

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Agglomération industrielle en Canada : application et développement des méthodologies spatiales et spatio-temporelles

Les choix de localisation des entreprises ainsi que les agglomérations industrielles sont un sujet clé dans le développement régional et l’aménagement territorial en raison des effets externes générés par ces mécanismes qui peuvent avoir un impact sur les inégalités régionales et également sur la productivité des firmes. En lien avec notre réalité actuelle, ces mécanismes […]

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Studies of CNNM-TRPM7 complexes

It has recently been shown that the tumour suppressor CNNM and TRPM7 bind each other and are coordinately regulated. We propose to determine the structure and function of the complex using cryoelectron microscopy and ion transport assays. A PhD student from the Gehring laboratory will spend four months working in the Runnels laboratory designing and […]

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Temperature de Conducteurs; Developpement des relations experimentales pour Ie dimensionnement des connexions flexibles des alternateurs

Le sujet a l’etude dans ce projet est le joint de cuivre flexible. Ces joints assurent une connexion electrique entre des conducteurs. Certains fabricants utilisent aujourd’hui ces joints flexibles dans les alternateurs pour faire les connexions entre les poles du rotor pour l’inducteur. Le dimensionnement de ces joints flexibles s’effectue avec une approche conservatrice compte […]

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Development of science-based criteria to assess the effectiveness of the ecological restoration of peatlands

Peatlands are freshwater wetlands which, in their natural (pristine) state, provide a specific habitat for many species of flora and fauna and several ecosystem services useful to human populations, such as the sequestration of carbon in accumulated peat (peatlands are a major global carbon sink). However, like many other wetlands, they are often disturbed and […]

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Digital Tools and Techniques to Enable Mass Customization of Prefabricated Housing Year Two

The intended research aims at bringing the design and production process of the industry partner, BONE STRUCTURE into a new level of customization, that involves effective homebuyers participation in the design of their homes, using cutting-edge computatioanl design techniques. The customization process is initiated with a layout design; roomblocks modifications, till selection of appliances and […]

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Systèmes microfluidiques sans perfusion fabricables en masse pour l’oncologie 3D

Les puces microfluidiques ont montré beaucoup de potentiel pour la culture d’échantillons de tumeurs à l’extérieur du corps (ex vivo). En conservant la viabilité des tumeurs jusqu’à 15 jours, elles ouvrent la voie vers des tests prédictifs de la réponse des patients au traitement avant même leur prescription. Toutefois, pour que la technologie soit commercialisable, […]

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