Radiation therapy treatment planning is a critical and highly complex step in cancer treatment, requiring significant expertise and time to adapt and personalize treatments to each patient’s condition. Current planning methods often rely on manual expertise and standardized approaches, which can limit the degree of personalization and contribute to variability in outcomes. This project addresses […]

This project aims to investigate whether the presence of Trichomonas vaginalis, the etiological agent responsible for the most common non-viral sexually transmitted infection worldwide, trichomoniasis, is able to impact the production of small vesicles by cervical cells. In addition, this project also proposes to investigate whether these small vesicles could result in the transformation of […]

The project uses large language models (LLMs) and information-theory measures to quantify how people think in real conversations. The goal is to create a pipeline that quantifies informational content (the purpose of the utterance is to provide/inquire information) and relational content (the purpose is to build a stronger relational bond with the other speaker) in […]

L’intelligence artificielle joue un rôle de plus en plus important dans le domaine de la santé, notamment grâce aux grands modèles de langage capables d’analyser de vastes volumes d’information médicale. Toutefois, ces systèmes demeurent souvent difficiles à interpréter, ce qui limite leur utilisation dans des contextes sensibles. Ce projet vise à développer des outils d’intelligence […]

This project aims to develop a reliable and easy-to-understand artificial intelligence tool that can help answer medical questions more safely and transparently. By improving how AI systems explain their answers, the project seeks to increase trust among healthcare professionals and patients while reducing the risk of incorrect or biased medical information. The collaboration between the […]

This project focuses on the design, synthesis and characterization of coiled coil (CC) motifs as modular scaffolds for metal-mediated assembly and function. CCs are predictable a-helical assemblies in which oligomerization behavior can be tuned through sequence design, making them attractive scaffolds for incorporating metal-binding functionalities in a controlled manner. In this project, CC motifs will […]

This project will test whether growth factors produced in-house at the host institute can reliably replace commercially purchased growth factors used to grow heart and kidney cells from human stem cells. These growth factors are essential but costly, and their performance can decline when they are repeatedly warmed and cooled during routine lab work. The […]

This project will study how different human antibodies help protect us from viruses such as influenza, SARS-CoV-2, and RSV by working with individual immune cells and producing their antibodies in the lab. The student will grow and purify these antibodies, test how well they bind to viruses, and measure how effectively they activate important immune […]

This project explores two critical areas of AI research: cybersecurity for Internet of Things (IoT) systems and responsible AI assistants for education and research. IoT devices, widely used in healthcare, smart cities, and industry, are highly vulnerable to cyberattacks due to limited resources and large-scale connectivity. We propose AI-based intrusion detection systems that are lightweight, […]

Proteins control nearly all biological processes in animals, including growth, metabolism, immunity, and responses to stress or disease. To understand how proteins work, scientists often need tools that can bind to them very specifically and stabilize them for study. Nanobodies are a new type of antibody fragment derived from camelids such as alpacas. Unlike traditional […]

Stress signaling in the brain is critical for adaptation in the face of various challenges. Adaptation to stress requires the engagement of specific brain circuits that control production of stress hormones including cortisol, including the hypothalamus-pituitary-adrenal (HPA) axis. Overactivation of HPA axis however, results in pathological stress that can contribute to psychiatric disorders including anxiety […]

Dentures are oral appliances or prosthetic devices that replace missing teeth and restore oral function, speech, and aesthetics. The denture market is driven mainly by the older adult population, which is expected to grow by 68% in the next 20 years according to the Canadian Institute for Health Information. These individuals often suffer from sleep-related […]