Development of a bacterial detection assay for point-of-care infection monitoring

Ineffective diagnosis of bacterial infections leads to excess healthcare costs of $25

billion/year worldwide due to transmission of infections while waiting for diagnosis,

unnecessary antibiotic treatments and resulting increased drug resistance, etc. Point-of-care

molecular testing can help provide timely and effective diagnoses leading to better (and more

cost-effective) patient management. Markets where point-of-care testing would make a large

difference are the hospital-acquired infections markets, sexually transmitted infection (STI)

market, and upper respiratory infections market.

This proposal will marry a unique bacterial detection strategy with a multiplexed chip-based

device for rapid analysis of infectious pathogens. The applicant, Dr. Das, has developed a

strategy that allows trace quantities of bacteria to be analyzed in 30 minutes or less. In the

proposed project, he will test whether it can be run on a multiplexed chip and whether the

resulting assay will be practical for use in a point-of-care testing system. The sponsor,

Xagenic (Canada) Inc., will benefit from this effort as it will speed the….

Faculty Supervisor:

Shana Kelley

Student:

Partner:

Xagenic Inc

Discipline:

Life Sciences

Sector:

University:

University of Toronto

Program:

Accelerate

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