Projets novateurs réalisés

Explorez des milliers de projets réussis issus de la collaboration entre organisations et talents postsecondaires.

30156 projets achevés

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812
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673
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842
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96
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579
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Projets par catégorie

Biomolecular Quantitation and Structure Analysis to Accelerate Development of New Vaccines

Manufacturing of consistently high quality products is the commitment of the pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing of biologic products which, relative to small molecular drugs, have a larger size, are more complex in structure and are thus more difficult to characterize. Modern instrumental analyses, including Mass Spectrometry, Nuclear Magnetic Resonance and Capillary Electrophoresis, are capable of high resolution and precision analyses of primary and higher order biomolecule structures and quantitation. Using these cutting-edge technologies, we are proposing to develop new methodologies to improve biomolecule characterization. TO BE CONT’D

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Superviseur du corps professoral :

Yi Sheng;Derek Wilson;Sergey Krylov

Étudiant :

Partenaire :

Sanofi

Discipline :

Life Sciences

Secteur :

Pharmaceuticals; Health and Related Sciences & Technology; Biotechnology

Université :

York University

Programme :

Accelerate

In-vivo translation of neuronal cell regeneration/reprogramming protein in mouse with chronic spinal cord injury

Chronic spinal cord injury (SCI) is a debilitating disease with enormous economic and personal impact. To date there is no approved treatment that can repair the severed nerves found in SCI. The research project entails translational development of an early stage experimental protein drug candidate that has shown remarkable ability to trigger dormant human stem cells to rapidly differentiate into functional neuronal populations. Both the drug candidate’s safe dosage range and efficacy in regenerating neurons at the site of injury will be studied. The goal of the project is to test the feasibility of this protein drug to enter clinical development.

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Superviseur du corps professoral :

Wolfram Tetzlaff

Étudiant :

Partenaire :

iProgen Biotech Inc

Discipline :

Life Sciences

Secteur :

Professional, scientific and technical services

Université :

The University of British Columbia

Programme :

Accelerate

Development and characterization of composites

In this project, Global Heat Transfer Ltd. (GHT) partners with the Composites & Optimization research group at the University of British Columbia in the Okanagan in order to integrate additive manufacturing into GHT’s current production line. Fabrication of high-performance compact radiator cores through additive manufacturing (AM) will not only resolve some of the current radiator manufacturing issues, but also will make the manufacturing process faster and environmentally friendlier. Without need for metal forming, machining, welding, brazing, and molds and dies, the AM technology, which is known as the third industrial revolution, will allow production of new high-performance thermoplastic composite radiator cores with complex three-dimensional configurations through a single-step process with no time penalty.

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Superviseur du corps professoral :

Abbas Milani

Étudiant :

Partenaire :

Global Heat Transfer Ltd

Discipline :

Engineering

Secteur :

Manufacturing

Université :

University of British Columbia - Okanagan

Programme :

Accelerate

Réalisation d’un laser à fibre haute puissance (kW) sans épissure

Les réseaux de Bragg à fibre optique (FBG) photo-inscrits par laser sont des composants essentiels à l’opération de lasers à fibre robustes. Traditionnellement, les FBG sont inscrits dans des fibres passives, qui sont ensuite fusionnées à la fibre active pour former la cavité laser. Cependant, en plus d’exiger de fastidieuses manipulations de fibres, les fusions entre fibre dissymétriques deviennent un point de défaillance critique lors de l’opération laser à très haute puissance moyenne (régime kilowatt continu). L’objectif du projet consiste à réaliser la démonstration d’une cavité laser monolithique (i.e. sans épissure) opérant à une puissance moyenne d’au moins 1 kilowatt en inscrivant les réseaux directement dans la fibre active par inscription laser femtoseconde. Le projet présente un fort intérêt industriel pour l’entreprise TeraXion qui se spécialise dans le développement et la commercialisation de FBG pour différentes applications.

Voir la description complète du projet
Superviseur du corps professoral :

Martin Bernier;Réal Vallée

Étudiant :

Partenaire :

TeraXion Inc (Québec, QC)

Discipline :

Physics

Secteur :

Manufacturing

Université :

Université Laval

Programme :

Accelerate

New statistical machine learning methods applied to high dimensional sensory input data from chemistry

Machine learning is the concept where a computer can be trained to recognize data and predict future outcomes based on the trends that exist in the data. This method of analysis has not been used on engine data, specifically in-line oil. Oil is an engine’s lifeblood and a lot of data can be collected and engine health can be predicted based on these measurements. This project aims to deploy machine learning concepts in the area of engine failure prediction. A special sensor equipped with the machine learning algorithm will be able to report all vital signs of an engine in a matter of minutes.

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Superviseur du corps professoral :

Linglong Kong

Étudiant :

Partenaire :

MaxFleet Solutions Ltd

Discipline :

Mathematics

Secteur :

Professional, scientific and technical services

Université :

University of Alberta

Programme :

Accelerate

Filling in the gaps of the IMD immune pathway of the kissing bug Rhodnius prolixus

Rhodnius prolixus is a hemathophagous insect that has served for decades as a model to study insect physiology. Rhodnius prolixus is also a major vector of Trypanosoma cruzi, the etiological agent of Chagas disease that kills 45,000 people annually and affects over 8 million people worldwide. The genome of R. prolixus contains ~15,500 predicted protein-coding genes. Many pathways such as the Toll and JAK-STAT pathways were present. Key components of the highly conserved IMD pathway, however, were not detected; this observation is also shared with other hemimetabolous insects: the pea aphid, the bedbug, and the head louse. Despite the fact that many genes of the IMD pathway are not found in the R. prolixus genome, effector immune genes normally regulated by the IMD pathway are still expressed after a bacterial infection. TO BE CONT’D

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Superviseur du corps professoral :

Carl Lowenberger

Étudiant :

Partenaire :

Universidade Federal do Rio de Janeiro

Discipline :

Life Sciences

Secteur :

Université :

Simon Fraser University

Programme :

Globalink Research Award

Income Inequality Based Variations in Trajectories of Brain and Psychopathology Development in Youth

Higher levels of income inequality is associated with poor mental and physical health. Often stress is considered the underlying factor creating poorer health outcomes in regions of higher inequality. Even with peaked interest in investigation of income inequality and health there has been no study of the association between income inequality and brain development. Moreover, the study of mental illness in relation to income inequality has not addressed the potential impact on the development of psychopathology in the pediatric population. We hypothesize that differences in income inequality will lead to variations in cortical brain development as well as differences in the risk mental illness and progression of symptoms. Therefore, the proposed research will investigate the association between income inequality and both brain and mental illness development in children and adolescents (age 6-18).

Voir la description complète du projet
Superviseur du corps professoral :

Tomas Paus

Étudiant :

Partenaire :

Universidade Federal do Rio Grande do Sul

Discipline :

Sociology

Secteur :

Université :

University of Toronto

Programme :

Globalink Research Award

Caractérisation des propriétés thermomécaniques des panneaux en nid d’abeille et optimisation de leurs configurations dans le design des réflecteurs d’antenne spatial

Étant donné que les technologies de l’information sont de plus en plus utilisées, les fournisseurs doivent assurer la maximisation de la bande passante de leurs installations en tout temps. Pour les réflecteurs embarqués sur les satellites, cela signifie qu’un minimum de distorsion thermique est souhaitable pour obtenir un maximum de performance. Ces distorsions thermiques apparaissent à cause de la contraction et la dilatation de la matière sous l’effet de la température. Ce défi est d’une importance cruciale du fait que les réflecteurs sont soumis à des excursions thermiques sévères. Pour s’assurer de minimisé ces distorsion, il faut premièrement s’assurer de bien comprendre le comportement des matériaux. Ensuite, il faut pouvoir simuler les effets de la température pour prévoir et optimiser la construction des réflecteurs. Ce projet se donne donc comme objectif de diminuer ces distorsions en optimisant la construction de ces réflecteurs, et ce

Voir la description complète du projet
Superviseur du corps professoral :

Louis Laberge Lebel

Étudiant :

Partenaire :

MacDonald, Dettwiler, and Associates Ltd (Sainte-Anne-de-Bellevue, QC)

Discipline :

Engineering

Secteur :

Information and cultural industries; Manufacturing; Professional, scientific and technical services

Université :

École Polytechnique de Montréal

Programme :

Accelerate

Predator Reduction and Habitat Influences: Impacts on Upland Duck Nest Success in Alberta Parklands

More than any other life stage, the hatching of eggs is the most important factor in the maintenance of dabbling duck populations. Rates of nest success are suppressed by predators like foxes, coyotes, skunks, and crows. Populations of these predators can be artificially high due to habitat alterations resulting from human development. The Delta Waterfowl Foundation proposes lethal trapping to reduce nest predation in Alberta parkland habitats. However, predator reduction programs can direct limited resources away from habitat-based alternatives, and are controversial. This project will evaluate the need for and efficacy of predator reduction. We will also investigate which habitat characteristics are associated with particularly high nest predation risk, attempting to improve non-invasive management options. In the 2017 nesting season, we will search trapped and non-trapped plots for duck nests, monitoring for nest success. TO BE CONT’D

Voir la description complète du projet
Superviseur du corps professoral :

Mark S Boyce

Étudiant :

Partenaire :

Delta Waterfowl Foundation

Discipline :

Earth science

Secteur :

Other services (except public administration)

Université :

University of Alberta

Programme :

Accelerate

Amélioration des protocoles et des architectures de communications inter-FPGA

La simulation en temps réel de système d’électronique de puissance et de réseau électrique exige de faibles pas de calcul afin d’obtenir une précision sur les phénomènes transitoires. Pour répondre au besoin de sa clientèle, OPAL-RT technologies offre des produits de pointe qui sont contraints par un problème non trivial, les délais de communication. Plus spécifiquement, la problématique porte sur les délais de communication entre les plateformes Field Programmable Gate Array (FPGA) qui limite la complexité et la dimension que pourraient atteindre les modèles de simulation. L’objectif de ce projet est de rechercher des méthodes permettant de diminuer la latence de communication inter-FPGA.

Voir la description complète du projet
Superviseur du corps professoral :

Daniel Massicotte

Étudiant :

Partenaire :

OPAL-RT Technologies Inc.

Discipline :

Engineering

Secteur :

Aerospace; Green/Alternative Energy; Energy and Utilities

Université :

Université du Québec à Trois-Rivières

Programme :

Accelerate

Microplastic pollution in coastal British Columbia: a baseline assessment of contamination in blue mussels

Microplastic pollution is an emerging threat to marine environments. Microplastics (small plastic polymers <5mm in diameter) are the result of large plastic pieces breaking down into smaller and smaller fragments when exposed to high temperatures and light. Beach litter contributes to microplastic pollution. Aquatic animals such as shellfish feed on microplastics resulting in negative health effects. In the proposed study, Julie Dimitrijevic will complete a three-part project to determine the accumulation rate of microplastics by blue mussels in southern British Columbia. Live mussels will be placed in the marine environment for 60 days to determine the number of microplastics consumed in the wild. A laboratory study will determine plastic pieces consumed compared to how many plastic pieces are rejected as “pseudofaeces” after filter feeding. Lastly, a global contamination snapshot will be developed using mussels provided from 18 international locations. TO BE CONT'D

Voir la description complète du projet
Superviseur du corps professoral :

Leah Bendell

Étudiant :

Partenaire :

Ocean Wise

Discipline :

Life Sciences

Secteur :

Arts, entertainment and recreation; Education; Other services (except public administration); Professional, scientific and technical services

Université :

Simon Fraser University

Programme :

Accelerate

Development of a model-based fuel supply control strategy for leak & fault detection in the fuel delivery system of a PEM Fuel Cell (FC) module

This proposed research project is an extension of a previous NSERC CRD project that is developing improved control of the hydrogen fuel supply to Proton Exchange Membrane Fuel Cells (PEMFCs) used in FC buses. The models developed in this research are expected to give improved hydrogen leak detection and fuel supply control during FC module operation by incorporating fuel leakage (internal or external to the module) in the fuel supply control approach from the outset; thus permitting estimation of the ongoing leakage in operation, and the ability to compensate for leakage in the control system to give extended lifetimes before servicing is necessary.

Voir la description complète du projet
Superviseur du corps professoral :

Farid Golnaraghi

Étudiant :

Partenaire :

Ballard Power Systems Inc

Discipline :

Engineering

Secteur :

Manufacturing; Professional, scientific and technical services

Université :

Simon Fraser University

Programme :

Accelerate

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