Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

29670 Completed Projects

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801
MB
663
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825
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8841
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95
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568
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Projects by Category

Modeling DNA Adducts as Cancer Diagnostic and Therapeutic Markers: Computational Chemistry Studies of the Structure-Function Relationships of DG-C8-A?C Adducts

Recent nucleic acids research has focused on the formation of genotoxic DNA adducts as covalent modifications of DNA that often result from carcinogen exposure; human-made chemicals can also cause DNA damage through bulky DNA adduct formation. DNA adducts are not only markers of carcinogenic exposure but also alter the regulation of oncogene transcription and standard DNA replication. A potent DNA adduct of A?C, a carcinogenic heterocyclic aromatic amine produced in high quantities in tobacco smoke, has been identified (dG-C8-A?C), but the exact pathways and outcomes of its replication by different DNA translesion polymerases involved in DNA repair remain largely unknown. Accordingly, they will be investigated with standard computational chemistry, namely density-functional theory and molecular dynamics simulations, to shed light on the structure-function of these bulky DNA adducts and their mutational signature associated with several cancers, yielding crucial information to exploit them as diagnostic or therapeutic markers of cancer.

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Faculty Supervisor:

Gilles Peslherbe

Student:

Partner:

Henan University of Technology

Discipline:

Physics

Sector:

Education

University:

Concordia University

Program:

Globalink Research Award

Synthesis an Characterization of luminescent Nanostructures

We use nanoscale gold particles to tune luminescence properties of light emitting lanthanide complexes. Metal nanoparticles, e.g. of gold and silver, absorb light in the visible region due to so-called plasmonic resonance. Thus, interaction between lanthanide luminescence and this resonance is expected. By varying the properties of the complex and the shape and surface of the nanoparticles the luminescence shall be tuned. The distance between the nanoparticle core and the emitting species is responsible for whether the luminescence is quenched or enhanced. In order to monitor this interaction lifetime measurement are necessary which will be carried out at Prof. Capobianco´s laboratory.

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Faculty Supervisor:

John Capobianco

Student:

Partner:

Universität zu Köln

Discipline:

Life Sciences

Sector:

Education

University:

Concordia University

Program:

Globalink Research Award

Computer Modeling of Protein-Nanoparticles Interactions for Nanomedicinal Applications: Binding Thermodynamics of Endohedral Metallofullerenes (Gd@C60) and Toll-like Receptor 5

carbon-cage nanoparticles, provide a meaningful approach to nanomedicine owing to their resistance to metabolism and kinetic stability, and confinement prevents direct binding of the toxic metal ions to cellular components. Conjugation of endohedral metallofullerenes with proteins could overcome many physiological issues such as low biocompatibility, and the interaction of these supramolecular assemblies warrants further investigation. In this project, the target protein is the toll-like receptor (TLR) 5, a pattern recognition receptor protein implicated in sensing invading virulent pathogen entry into host cells and causing a pro-inflammatory response to eliminate the pathogens. Computer modeling via density-functional theory and molecular dynamics simulations of the TLR5 interaction with endohedral metallofullerenes such as gadofullerenes will thus be carried out in order to explore and possibly guide the design of low-dosage, high-efficacy imaging contrast agents, drug targets or cancer therapeutics.

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Faculty Supervisor:

Gilles Peslherbe

Student:

Partner:

Henan University of Technology

Discipline:

Physics

Sector:

Education

University:

Concordia University

Program:

Globalink Research Award

Sexually transmitted infections in immigrant and refugee populations in situation of social vulnerability in the state of Goiás-Brazil.

This projects aims to support the data collection of a mix-method study to be implemented by a team of 6 undergraduate students. The study investigates the epidemiology and the lived experience of sexually transmitted infections of socially vulnerable English, Spanish and French speakers, immigrants/refugees. It will be done by uncovering issues of sexual and reproductive health as well as risk behaviours for these infections. The research sites are the cities of Aparecida de Goiânia, Goiânia and Anápolis (state of Goiás, Brazil).

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Faculty Supervisor:

Margareth Zanchetta

Student:

Partner:

Universidade Federal de Goiás

Discipline:

Life Sciences

Sector:

Education

University:

Toronto Metropolitan University

Program:

Globalink Research Award

Sexually transmitted infections in immigrant and refugee populations in situation of social vulnerability in the state of Goiás-Brazil.

This project aims to support the data collection of a mix-method study to be implemented by a team of 6 undergraduate students. The study investigates the epidemiology and the lived experience of sexually transmitted infections of socially vulnerable English, Spanish and French speakers, immigrants/refugees. It will be done by uncovering issues of sexual and reproductive health as well as risk behaviours for these infections. The research sites are the cities of Aparecida de Goiânia, Goiânia and Anápolis (state of Goiás, Brazil)

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Faculty Supervisor:

Margareth Zanchetta

Student:

Partner:

Universidade Federal de Goiás

Discipline:

Sociology

Sector:

Education

University:

Toronto Metropolitan University

Program:

Globalink Research Award

Sexually transmitted infections in immigrant and refugee populations in situation of social vulnerability in the state of Goiás-Brazil.

This project aims to support the data collection of a mix-method study to be implemented by a team of 6 undergraduate students. The study investigates the epidemiology and the lived experience of sexually transmitted infections of socially vulnerable English, Spanish and French speakers, immigrants/refugees. It will be done by uncovering issues of sexual and reproductive health as well as risk behaviours for these infections. The research sites are the cities of Aparecida de Goiânia, Goiânia and Anápolis (state of Goiás, Brazil).

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Faculty Supervisor:

Margareth Zanchetta

Student:

Partner:

Universidade Federal de Goiás

Discipline:

Life Sciences

Sector:

Education

University:

Toronto Metropolitan University

Program:

Globalink Research Award

Sexually transmitted infections in immigrant and refugee populations in situation of social vulnerability in the state of Goiás-Brazil.

This project aims to support the data collection of a mix-method study to be implemented by a team of 6 undergraduate students. The study investigates the epidemiology and the lived experience of sexually transmitted infections of socially vulnerable English, Spanish and French speakers, immigrants/refugees. It will be done by uncovering issues of sexual and reproductive health as well as risk behaviours for these infections. The research sites are the cities of Aparecida de Goiânia, Goiânia and Anápolis (state of Goiás, Brazil).

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Faculty Supervisor:

Sepali Guruge;Margareth Zanchetta

Student:

Partner:

Universidade Federal de Goiás

Discipline:

Sociology

Sector:

Education

University:

Toronto Metropolitan University

Program:

Globalink Research Award

Identification of geological controls on productivity of low-permeability reservoirs using multivariate statistics

The Montney and the Duvernay formations, both are prolific low-permeability reservoirs currently developed using multi-fractured horizontal wells. Taking advantage of the enormous well database from these reservoirs, we aim to identify the key geological parameters controlling the well performance. Overall, a combination of nearly 40 different variables per well are known for affecting the reservoir performance (e.g. depth, thermal maturity, brittleness, lateral length, well spacing, proppant type, etc). Thus, using multi-variate statistics and advanced methods for visualization of data, we will explore relationships and patterns that suggest which are dominant geological factors, and further to stablish sensitivity analyses to recognize the degree at which each variable affects the well productivity. Approaches from this study can be replicated in other unconventional resources and will help to accelerate the learning curve during exploration.

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Faculty Supervisor:

Per Kent Pedersen

Student:

Partner:

Equinor Canada Ltd

Discipline:

Earth science

Sector:

Mining

University:

University of Calgary

Program:

Accelerate

Physiotherapy balls with pressure sensor

Today, physiotherapy balls or physioballs play an essential role in treating disability or body damages such as neck, waist, knee and so on. Despite their wide range of applications and importance, it is difficult to monitor the damaged member and propose continuous treatment in the presence of a physiotherapist or physician. This causes several problems and costs for the patient. Therefore, a new generation of physiotherapy balls will be created in this project. The idea is to perform exercises and monitoring without the need and/or the presence of a doctor or physiotherapist. This can be of great help for the restoration of a damaged muscle/member or to get a history of the continuous treatment.

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Faculty Supervisor:

Denis Rodrigue

Student:

Partner:

VMOpro Inc

Discipline:

Engineering

Sector:

Professional, scientific and technical services

University:

Université Laval

Program:

Accelerate

Sexually transmitted infections in immigrant and refugee populations in the state of Goias-Brazil

This projects aims to support the data collection of a mix-method study to be implemented by a team of 6 undergraduate students. The study investigates the epidemiology and the lived experience of sexually transmitted infections of socially vulnerable English, Spanish and French speakers, immigrants/refugees. It will be done by uncovering issues of sexual and reproductive health as well as risk behaviours for these infections. The research sites are the cities of Aparecida de Goiânia, Goiânia and Anápolis (state of Goiás, Brazil).

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Faculty Supervisor:

Sepali Guruge;Margareth Zanchetta

Student:

Partner:

Universidade Federal de Goiás

Discipline:

Life Sciences

Sector:

Education

University:

Toronto Metropolitan University

Program:

Globalink Research Award

Corrosion of Galvanized Steel Reinforcement in Mechanically Stabilized Earth Walls

The uses of Mechanically Stabilized Earth (MSE) walls and facings have gained widespread acceptance in North America for the past 30 years, as evidenced by the numerous completed structures. Exposure of MSE walls and facings to aggressive conditions could lead to early failure, and areas exposed to de-icing salts tend to present conditions similar to aggressive environments. This project seeks to attain a better understanding of the corrosion behavior of galvanized steel when exposed to de-icing salts and other environmental pollutants. The research will be highly beneficial to understand the corrosion behavior of MSE walls and facings. The results of this work are of importance to the private sector, and also to the transportation and public sectors in Canada. The benefits of the work to Canada and the sponsor are significant and will have an impact on the ability of other Canadian companies to compete efficiently in the global market.

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Faculty Supervisor:

Akram Alfantazi

Student:

Partner:

Transportation and Infrastructure BC

Discipline:

Engineering

Sector:

University:

The University of British Columbia

Program:

Accelerate

Onsite Monitoring and Progress Reporting

Construction projects are complex, unstructured and dynamic. So accurate project progress monitoring has always been an essential part of the project control plan and one of the main challenges for project managers. In fact in order to deliver projects on time and within budget, progress monitoring can be taken in to account as a critical success factor. In the current practices, project progress monitoring is performed manually which is time consuming, expensive and error prone. In this research project near real-time site data acquisition and construction progress monitoring on daily basis are performed using novel technologies and algorithms respectively. Moreover construction industry sectors are suffering from poor material management processes, however materials and installed equipment can make up 50– 60% of the total project cost and impact 80% of its schedule. So accurate project progress measurement through developed method can improve materials management as well.

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Faculty Supervisor:

Osama Moselhi

Student:

Partner:

Pomerleau

Discipline:

Engineering

Sector:

Construction and infrastructure

University:

Concordia University

Program:

Accelerate

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